Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise
暂无分享,去创建一个
T. Bruxner | R. Meehan | C. Nestor | S. Chong | E. Whitelaw | A. Ashe | Nadia C Whitelaw | Eleanore H. Lambley | Daniel K Morgan
[1] Alexander van Oudenaarden,et al. Variability in gene expression underlies incomplete penetrance , 2009, Nature.
[2] Young-Joon Kim,et al. Intrinsic variability of gene expression encoded in nucleosome positioning sequences , 2009, Nature Genetics.
[3] J. A. Halliday,et al. Transcriptional Infidelity Promotes Heritable Phenotypic Change in a Bistable Gene Network , 2009, PLoS biology.
[4] T. Bruxner,et al. A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development , 2008, Genome Biology.
[5] C. Sandi,et al. KAP1-Mediated Epigenetic Repression in the Forebrain Modulates Behavioral Vulnerability to Stress , 2008, Neuron.
[6] E. O’Shea,et al. Chromatin decouples promoter threshold from dynamic range , 2008, Nature.
[7] G. Kay,et al. SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation , 2008, Nature Genetics.
[8] S. Santos,et al. Mas Deficiency in FVB/N Mice Produces Marked Changes in Lipid and Glycemic Metabolism , 2008, Diabetes.
[9] J. Opitz,et al. Obesity: Genetic, molecular, and environmental aspects , 2007, American journal of medical genetics. Part A.
[10] T. Mikkelsen,et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells , 2007, Nature.
[11] H. Scott,et al. Modifiers of epigenetic reprogramming show paternal effects in the mouse , 2007, Nature Genetics.
[12] Farren J. Isaacs,et al. Phenotypic consequences of promoter-mediated transcriptional noise. , 2006, Molecular cell.
[13] T. Clark,et al. Estimating the number of coding mutations in genotypic and phenotypic driven N-ethyl-N-nitrosourea (ENU) screens: revisited , 2006, Mammalian Genome.
[14] T. Bruxner,et al. An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[15] K. Mather,et al. Heritable variation in a long inbred line of drosophila , 1955, Genetica.
[16] J. Raser,et al. Control of Stochasticity in Eukaryotic Gene Expression , 2004, Science.
[17] A. Skoultchi,et al. The ISWI ATPase Snf2h is required for early mouse development , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[18] Mads Kærn,et al. Noise in eukaryotic gene expression , 2003, Nature.
[19] D. O’Carroll,et al. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression , 2002, The EMBO journal.
[20] G. Maul,et al. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. , 2002, Genes & development.
[21] Karl Mechtler,et al. Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability , 2001, Cell.
[22] J. Friedman,et al. Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. , 2001, Genes & development.
[23] P. Chambon,et al. Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development. , 2000, Development.
[24] D. Haber,et al. DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development , 1999, Cell.
[25] L Young,et al. The Jackson Laboratory , 1998, Molecular medicine.
[26] Rudolf Jaenisch,et al. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality , 1992, Cell.
[27] K. Gärtner,et al. A third component causing random variability beside environment and genotype. A reason for the limited success of a 30 year long effort to standardize laboratory animals? , 1990, Laboratory animals.
[28] A. Griffiths. Introduction to Genetic Analysis , 1976 .
[29] D. Falconer. The genetics of litter size in mice. , 1960, Journal of cellular and comparative physiology.
[30] DONALD MICHIE,et al. Variance Control in the Animal House , 1958, Nature.
[31] C. Waddington. Canalization of Development and the Inheritance of Acquired Characters , 1942, Nature.