Renal artery revascularization: predictive value of kidney length and volume weighted by resistive index.

OBJECTIVE The purpose of this study was to evaluate the usefulness of renal length, volume, and resistive index measurements at Doppler ultrasound and MR angiography in predicting improvement after renal angioplasty. MATERIALS AND METHODS Fifty-one patients underwent Doppler ultrasound examinations and MR angiography before percutaneous transluminal renal angioplasty. Renal length, total and cortical volumes, and resistive index were calculated. Combinations of length, volume, and resistive index measurements were correlated with improvement in blood pressure and renal function after percutaneous transluminal renal angioplasty. Thresholds for improving patient selection were chosen after analysis of receiver operating characteristics curves. RESULTS Lower total and cortical volumes on MR angiograms and shorter kidney length on Doppler ultrasound images were found among patients with successful blood pressure control (p = 0.042, p = 0.035, and p = 0.016, respectively). Renal length measured with Doppler ultrasound and cortical volume measured with MR angiography weighted by resistive index were the best predictive factors (p = 0.004, p = 0.006). Using a threshold of renal length-resistive index product less than 7 cm, therapeutic response was predicted with a sensitivity of 87% and specificity of 50%, whereas with a threshold value of 52 mL/m(2) for cortical renal volume-resistive index product divided by body surface area, sensitivity of 86% and specificity of 50% were obtained. CONCLUSION Renal length and volume combined with resistive index measurements appear to be predictive of therapeutic response after percutaneous transluminal renal angioplasty.

[1]  P. Devos,et al.  [Clinic and morphologic evolution five years after a renal atherosclerotic artery stenosis (RAS): a study of twenty nine hypertensive patients population]. , 2004, Archives des maladies du coeur et des vaisseaux.

[2]  H. Haller,et al.  Techniques for predicting a favourable response to renal angioplasty in patients with renovascular disease , 2001, Current opinion in nephrology and hypertension.

[3]  R. D'Agostino,et al.  Stent revascularization for the prevention of cardiovascular and renal events among patients with renal artery stenosis and systolic hypertension: rationale and design of the CORAL trial. , 2006, American heart journal.

[4]  A. Logan,et al.  Balloon angioplasty or medical therapy for hypertensive patients with atherosclerotic renal artery stenosis? A meta-analysis of randomized controlled trials. , 2003, The American journal of medicine.

[5]  Y. Kikuchi,et al.  Correlation between the resistive index by Doppler ultrasound and kidney function and histology. , 2005, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[6]  G. Soulez,et al.  Percutaneous revascularization of the renal arteries: predictors of outcome. , 2000, Journal of vascular and interventional radiology : JVIR.

[7]  D. DuBois,et al.  A formula to estimate the approximate surface area if height and weight be known , 1989 .

[8]  D. D. Bois,et al.  CLINICAL CALORIMETRY: TENTH PAPER A FORMULA TO ESTIMATE THE APPROXIMATE SURFACE AREA IF HEIGHT AND WEIGHT BE KNOWN , 1916 .

[9]  Thomas S Sørensen,et al.  Different strategies for MRI measurements of renal cortical volume , 2007, Journal of magnetic resonance imaging : JMRI.

[10]  H. Jacobson,et al.  Ischemic renal disease: an overlooked clinical entity? , 1988, Kidney international.

[11]  Marc S. Schwartzberg,et al.  Quality improvement guidelines for angiography, angioplasty, and stent placement in the diagnosis and treatment of renal artery stenosis in adults. , 2002, Journal of vascular and interventional radiology : JVIR.

[12]  Serge Willoteaux,et al.  Cortical thickness: an early morphological marker of atherosclerotic renal disease. , 2002, Kidney international.

[13]  Nicolas Grenier,et al.  Update of renal imaging. , 2006, Seminars in nuclear medicine.

[14]  G. Soulez,et al.  Renal angioplasty and stenting. , 2001, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes.

[15]  M. Chonchol,et al.  Diagnosis and management of ischemic nephropathy. , 2006, Clinical journal of the American Society of Nephrology : CJASN.

[16]  Raja Muthupillai,et al.  Normal values for renal length and volume as measured by magnetic resonance imaging. , 2006, Clinical journal of the American Society of Nephrology : CJASN.

[17]  Rob J van der Geest,et al.  Functional renal volume: quantitative analysis at gadolinium-enhanced MR angiography--feasibility study in healthy potential kidney donors. , 2005, Radiology.

[18]  S. Textor Atherosclerotic renal artery stenosis: overtreated but underrated? , 2008, Journal of the American Society of Nephrology : JASN.

[19]  F. Neumann,et al.  Stent-Supported Angioplasty of Severe Atherosclerotic Renal Artery Stenosis Preserves Renal Function and Improves Blood Pressure Control: Long-Term Results from a Prospective Registry of 456 Lesions , 2004, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

[20]  R. Katholi,et al.  Clinical predictors of improved long‐term blood pressure control after successful stenting of hypertensive patients with obstructive renal artery atherosclerosis , 1999, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[21]  G. Soulez,et al.  Prediction of clinical response after renal angioplasty: respective value of renal Doppler sonography and scintigraphy. , 2003, AJR. American journal of roentgenology.

[22]  Cockcroft Dw,et al.  Prediction of Creatinine Clearance from Serum Creatinine , 1976 .

[23]  Satoko Nakamura,et al.  Relationship between renal artery stenosis and intrarenal damage in autopsy subjects with stroke. , 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[24]  F. Shellock,et al.  MRI safety update 2008: part 1, MRI contrast agents and nephrogenic systemic fibrosis. , 2008, AJR. American journal of roentgenology.

[25]  P. Lennox,et al.  Sedation and analgesia in the interventional radiology department. , 2003, Journal of vascular and interventional radiology : JVIR.

[26]  J. Radermacher Echo-doppler to predict the outcome for renal artery stenosis. , 2002, Journal of nephrology.

[27]  P. Krijnen,et al.  The effect of balloon angioplasty on hypertension in atherosclerotic renal-artery stenosis. Dutch Renal Artery Stenosis Intervention Cooperative Study Group. , 2000, The New England journal of medicine.

[28]  T. Zeller Thirty years of revascularisation of renal artery stenosis. Increasing experience but still limited evidence. , 2007, The Journal of cardiovascular surgery.

[29]  M. Bettmann,et al.  Guidelines for the Reporting of Renal Artery Revascularization in Clinical Trials , 2002, Journal of vascular and interventional radiology : JVIR.

[30]  N. Ives,et al.  Angioplasty and STent for Renal Artery Lesions (ASTRAL trial): rationale, methods and results so far , 2007, Journal of Human Hypertension.

[31]  M Galanski,et al.  Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. , 2001, The New England journal of medicine.

[32]  S. Textor Renovascular hypertension in 2007: Where are we now? , 2007, Current cardiology reports.

[33]  S. Textor Renovascular hypertension: is there still a role for stent revascularization? , 2013, Current opinion in nephrology and hypertension.

[34]  W. Mali,et al.  Arterial stenting and balloon angioplasty in ostial atherosclerotic renovascular disease: a randomised trial , 1999, The Lancet.

[35]  A. Gottsäter,et al.  Sustained beneficial effects on blood pressure during long time retrospective follow-up after endovascular treatment of renal artery occlusion , 2004, Journal of Human Hypertension.

[36]  S. Haulon,et al.  Changes in renal blood flow reserve after angioplasty of renal artery stenosis in hypertensive patients. , 2004, Kidney international.

[37]  Michaela Schmidt,et al.  Can MR Measurement of Renal Artery Flow and Renal Volume Predict the Outcome of Percutaneous Transluminal Renal Angioplasty? , 2001, CardioVascular and Interventional Radiology.

[38]  Ewout Steyerberg,et al.  A Clinical Prediction Rule for Renal Artery Stenosis , 1998, Annals of Internal Medicine.

[39]  D. Bouley,et al.  Measurement of renal volumes with contrast‐enhanced MRI , 2002, Journal of magnetic resonance imaging : JMRI.