Assessment of Prunus amygdalus Gum for Functionality of Tablet Excipient

The aim of the research work is to assess the Purnus amygdalus gum for the potentiality of tablets binder / disintegrant excipient and potato starch was used as standard excipients. The gum was assessed for various tests. Ibuprofen was used as a model drug for the preparation of tablets. Totally eight batches were developed using various compositions. Preformulation and post formulation study were performed for the tablets. Also the tablets qualities were compared with innovator tablet. FTIR studies ruled out the drug excipient interaction. The hardness of the tablets were in the acceptable range. Disintegration time was ~4 minutes. Dissolution were between 70 – 89%. The results of the study describe that the Purnus amygdalus gum (PA ) could be alternative tablet excipients for potato starch.

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