Learning to predict health status of geriatric patients from observational data

Data for diagnosis and clinical studies are now typically gathered by hand. While more detailed, exhaustive behavioral assessments scales have been developed, they have the drawback of being too time consuming and manual assessment can be subjective. Besides, clinical knowledge is required for accurate manual assessment, for which extensive training is needed. Therefore our great research challenge is to leverage machine learning techniques to better understand patients health status automatically based on continuous computer observations. In this paper, we study the problem of health status prediction for geriatric patients using observational data. In the first part of this paper, we propose a distance metric learning algorithm to learn a Mahalanobis distance which is more precise for similarity measures. In the second part, we propose a robust classifier based on ℓ2,1-norm regression to predict the geriatric patients' health status. We test the algorithm on a dataset collected from a nursing home. Experiment shows that our algorithm achieves encouraging performance.

[1]  Chih-Jen Lin,et al.  LIBSVM: A library for support vector machines , 2011, TIST.

[2]  Kilian Q. Weinberger,et al.  Metric Learning for Kernel Regression , 2007, AISTATS.

[3]  M. Lawton,et al.  Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living , 1969 .

[4]  Ian T. Jolliffe,et al.  Principal Component Analysis , 2002, International Encyclopedia of Statistical Science.

[5]  E. Bleuler,et al.  Mood disorders. , 1984, American family physician.

[6]  Nicu Sebe,et al.  Exploiting the entire feature space with sparsity for automatic image annotation , 2011, ACM Multimedia.

[7]  David J. Kriegman,et al.  Eigenfaces vs. Fisherfaces: Recognition Using Class Specific Linear Projection , 1996, ECCV.

[8]  N. Castle,et al.  Measuring staff turnover in nursing homes. , 2006, The Gerontologist.

[9]  P. Mahalanobis On the generalized distance in statistics , 1936 .

[10]  Wilbert S Aronow,et al.  Demographics and payment characteristics of nursing home residents in the United States: a 23-year trend. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

[11]  Feiping Nie,et al.  Efficient and Robust Feature Selection via Joint ℓ2, 1-Norms Minimization , 2010, NIPS.

[12]  Yi Yang,et al.  A Multimedia Retrieval Framework Based on Semi-Supervised Ranking and Relevance Feedback , 2012, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[13]  Brian R. Ott,et al.  The Cornell-Brown Scale for Quality of Life in Dementia , 2002, Alzheimer disease and associated disorders.

[14]  Nicu Sebe,et al.  Web Image Annotation Via Subspace-Sparsity Collaborated Feature Selection , 2012, IEEE Transactions on Multimedia.

[15]  Yi Yang,et al.  Learning a 3D Human Pose Distance Metric from Geometric Pose Descriptor , 2011, IEEE Transactions on Visualization and Computer Graphics.

[16]  Michael I. Jordan,et al.  Distance Metric Learning with Application to Clustering with Side-Information , 2002, NIPS.

[17]  Sati Mazumdar,et al.  Rating chronic medical illness burden in geropsychiatric practice and research: Application of the Cumulative Illness Rating Scale , 1992, Psychiatry Research.

[18]  Zi Huang,et al.  Proceedings of the Twenty-Second International Joint Conference on Artificial Intelligence ℓ2,1-Norm Regularized Discriminative Feature Selection for Unsupervised Learning , 2022 .

[19]  Inderjit S. Dhillon,et al.  Structured metric learning for high dimensional problems , 2008, KDD.