Intravenous sulfamethoxazole-trimethoprim plus ticarcillin as empiric antibiotic therapy for granulocytopenic patient.

Infection is particularly common during periods of prolonged, profound granulocytopenia, with most Gramnegative rod bacteremias occurring when the granulocyte count is less than 100/μL. The signs and symptoms of infection in granulocytopenic patients are minimal, making early detection of infection difficult. Fever, however, is nearly universal and represents the initial clue to infection in these patients. The presence of fever (temperature greater than 37.3 °C [101 °F]) and granulocytopenia (

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