Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy.
暂无分享,去创建一个
[1] Talicia A Tarver. HEART DISEASE AND STROKE STATISTICS–2014 UPDATE: A REPORT FROM THE AMERICAN HEART ASSOCIATION , 2014 .
[2] J. Sadoshima,et al. Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion , 2012, Autophagy.
[3] M. Seishima,et al. The role of autophagy emerging in postinfarction cardiac remodelling. , 2011, Cardiovascular research.
[4] C. Baines. The Mitochondrial Permeability Transition Pore and the Cardiac Necrotic Program , 2011, Pediatric Cardiology.
[5] Jun Zhang,et al. Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS s1177/NO/DCC feed-forward mechanism. , 2010, Journal of molecular and cellular cardiology.
[6] H. Augustin,et al. Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. , 2009, The Journal of clinical investigation.
[7] M. Bilodeau,et al. Kv1.5 blockers for the treatment of atrial fibrillation: approaches to optimization of potency and selectivity and translation to in vivo pharmacology. , 2009, Current topics in medicinal chemistry.
[8] R. Gottlieb,et al. Autophagy in Ischemic Heart Disease , 2009, Circulation research.
[9] J. Youn,et al. An Ezrin/Calpain/PI3K/AMPK/eNOSs1179 Signaling Cascade Mediating VEGF-Dependent Endothelial Nitric Oxide Production , 2008, Circulation research.
[10] J. Zweier,et al. Cardiac Myocyte–Specific Expression of Inducible Nitric Oxide Synthase Protects Against Ischemia/Reperfusion Injury by Preventing Mitochondrial Permeability Transition , 2008, Circulation.
[11] M. Tessier-Lavigne,et al. Netrin-1 inhibits sprouting angiogenesis in developing avian embryos. , 2008, Developmental biology.
[12] N. Bryan,et al. Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury , 2007, Proceedings of the National Academy of Sciences.
[13] Christian Fischer,et al. Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. , 2007, Genes & development.
[14] F. Van de Werf,et al. Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion. , 2007, Journal of the American College of Cardiology.
[15] Z. Elazar,et al. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 , 2007, The EMBO journal.
[16] V. Cirulli,et al. Netrins: beyond the brain , 2007, Nature Reviews Molecular Cell Biology.
[17] H. Cai,et al. Attenuation of Angiotensin II Signaling Recouples eNOS and Inhibits Nonendothelial NOX Activity in Diabetic Mice , 2007, Diabetes.
[18] Hua “Linda” Cai,et al. Netrin‐1 induces angiogenesis via a DCC dependent ERK1/2‐eNOS feed‐forward mechanism , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[19] Lin Yan,et al. Autophagy in chronically ischemic myocardium. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[20] Mark R. Duranski,et al. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. , 2005, The Journal of clinical investigation.
[21] Jeffrey Robbins,et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death , 2005, Nature.
[22] F. Giancotti,et al. Netrin-Integrin Signaling in Epithelial Morphogenesis, Axon Guidance and Vascular Patterning , 2005, Cell cycle.
[23] L. Toledo-Pereyra,et al. Molecular signaling pathways in ischemia/reperfusion. , 2004, Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
[24] A. B. Huber,et al. Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. , 2003, Annual review of neuroscience.
[25] M. Tessier-Lavigne,et al. Recognition of the Neural Chemoattractant Netrin-1 by Integrins α6β4 and α3β1 Regulates Epithelial Cell Adhesion and Migration , 2003 .
[26] D. Stewart,et al. Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. , 2002, The Journal of clinical investigation.
[27] S. Jang,et al. Nitric oxide as a pro-apoptotic as well as anti-apoptotic modulator. , 2002, Journal of biochemistry and molecular biology.
[28] R. de Caterina,et al. Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts. , 2001, Cardiovascular research.
[29] R. Zamora,et al. The regulatory role of nitric oxide in apoptosis. , 2001, International immunopharmacology.
[30] Steven J. Sollott,et al. Reactive Oxygen Species (Ros-Induced) Ros Release , 2000, The Journal of experimental medicine.
[31] S. Davidge,et al. Activation of Ca(2+)-independent nitric oxide synthase by 17beta-estradiol in post-ischemic rat heart. , 2000, Cardiovascular research.
[32] S. Zahler,et al. Sodium nitroprusside in patients with compromised left ventricular function undergoing coronary bypass: reduction of cardiac proinflammatory substances. , 2000, The Journal of thoracic and cardiovascular surgery.
[33] P. Huang,et al. Myocardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase. , 1999, The American journal of physiology.
[34] S. Javadov,et al. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. , 1998, Biochimica et biophysica acta.
[35] Hao Wang,et al. Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System , 1996, Cell.
[36] B. F. Becker,et al. Nitric Oxide Accounts for Postischemic Cardioprotection Resulting from Angiotensin‐Converting Enzyme Inhibition: Indirect Evidence for a Radical Scavenger Effect in Isolated Guinea Pig Heart , 1995, Journal of cardiovascular pharmacology.
[37] Timothy E. Kennedy,et al. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord , 1994, Cell.
[38] T. Jessell,et al. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6 , 1994, Cell.
[39] A. M. Lefer,et al. Beneficial effects of SPM-5185, a cysteine-containing NO donor in myocardial ischemia-reperfusion. , 1992, The American journal of physiology.
[40] M. Crompton,et al. Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A. , 1991, Journal of molecular and cellular cardiology.
[41] R. Bolli,et al. Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[42] M. Crompton,et al. Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. , 1988, The Biochemical journal.
[43] M. Crompton,et al. Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria. , 1987, The Biochemical journal.
[44] P. Ping,et al. Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS. , 2015, Journal of molecular and cellular cardiology.
[45] D. Lefer,et al. Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway. , 2007, American journal of physiology. Heart and circulatory physiology.
[46] Steven P Jones,et al. The ubiquitous role of nitric oxide in cardioprotection. , 2006, Journal of molecular and cellular cardiology.
[47] M. Tessier-Lavigne,et al. Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration. , 2003, Developmental cell.
[48] A. Buda,et al. Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion. , 1996, Circulation research.