Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study

We propose a system for time-domain diffuse optical spectroscopy extending up to 1300 nm based on a su-percontinuum source and time-correlated single photon counting detection. The system was validated on liquid phantoms demonstrating a good linearity up to an absorption coefficient of 2.0 cm-1. Preliminary measurements on collagen powder reveal an important absorption peak around 1200 nm. Feasibility of in vivo diffuse optical spectroscopy on the female breast is demonstrated up to 1200 nm at an interfiber distance of 2 cm.