Allelic variants of IL1R1 gene associate with severe hand osteoarthritis

[1]  L. Ala‐Kokko,et al.  Association Between Interleukin 1 Gene Cluster Polymorphisms and Bilateral Distal Interphalangeal Osteoarthritis , 2009, The Journal of Rheumatology.

[2]  C. Jorgensen,et al.  Erosive osteoarthritis of the hand: clinical experience with anakinra , 2009, Annals of the rheumatic diseases.

[3]  D. Shi,et al.  Genetic polymorphisms of interleukin-1β (−511C/T) and interleukin-1 receptor antagonist (86-bpVNTR) in susceptibility to knee osteoarthritis in a Chinese Han population , 2009, Rheumatology International.

[4]  N. Hamajima,et al.  Interleukin-1β gene polymorphism associated with radiographic signs of osteoarthritis of the knee , 2008, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[5]  B. Riley,et al.  Potential influence of IL1B haplotype and IL1A-IL1B-IL1RN extended haplotype on hand osteoarthritis risk. , 2007, Osteoarthritis and cartilage.

[6]  J. Kaprio,et al.  Heritability of low back pain and the role of disc degeneration , 2007, PAIN.

[7]  M. Erdal,et al.  Lack of association polymorphisms of the IL1RN, IL1A, and IL1B genes with knee osteoarthritis in Turkish patients. , 2007, Clinical and investigative medicine. Medecine clinique et experimentale.

[8]  Laurence Meyer,et al.  Exhaustive genotyping of the interleukin-1 family genes and associations with AIDS progression in a French cohort. , 2006, The Journal of infectious diseases.

[9]  T. Spector,et al.  Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of quantitative trait loci on chromosomes 2 and 19 , 2006, Annals of the rheumatic diseases.

[10]  E. Schor,et al.  Polymorphisms in Exons 1B and 1C of the Type I Interleukin‐1 Receptor Gene in Patients with Endometriosis , 2006, American journal of reproductive immunology.

[11]  S. Jimenez,et al.  NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis , 2006 .

[12]  J. Li,et al.  Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix , 2005, Heredity.

[13]  L. Peltonen,et al.  Evaluating whole genome amplification via multiply-primed rolling circle amplification for SNP genotyping of samples with low DNA yield. , 2005, Twin research and human genetics : the official journal of the International Society for Twin Studies.

[14]  J. Houwing-Duistermaat,et al.  Association of the risk of osteoarthritis with high innate production of interleukin-1beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation. , 2005, Arthritis and rheumatism.

[15]  M. Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[16]  M. Doherty,et al.  Extended haplotypes and linkage disequilibrium in the IL1R1–IL1A–IL1B–IL1RN gene cluster: association with knee osteoarthritis , 2004, Genes and Immunity.

[17]  S. Griffin,et al.  A Functional Polymorphism in the Interleukin-1 Receptor-1 Gene Is Associated with Increased Risk of Helicobacter pylori Infection but Not with Gastric Cancer , 2004, Digestive Diseases and Sciences.

[18]  C. Stansberg,et al.  The interleukin 1 receptor family. , 2004, Developmental and comparative immunology.

[19]  J. Sims,et al.  Interleukin (IL)-1F6, IL-1F8, and IL-1F9 Signal through IL-1Rrp2 and IL-1RAcP to Activate the Pathway Leading to NF-κB and MAPKs* , 2004, Journal of Biological Chemistry.

[20]  P. Slagboom,et al.  Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip. , 2004, Arthritis and rheumatism.

[21]  D. Nyholt A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. , 2004, American journal of human genetics.

[22]  M. Boehnke,et al.  Assessing whether an allele can account in part for a linkage signal: the Genotype-IBD Sharing Test (GIST). , 2004, American journal of human genetics.

[23]  P. Robbins,et al.  Osteoarthritis gene therapy , 2004, Gene Therapy.

[24]  Peter Donnelly,et al.  A comparison of bayesian methods for haplotype reconstruction from population genotype data. , 2003, American journal of human genetics.

[25]  A. Palotie,et al.  Analysis of Genetic Variation in the GenomEUtwin Project , 2003, Twin Research.

[26]  J. Arokoski,et al.  Osteoarthritis of finger joints in Finns aged 30 or over: prevalence, determinants, and association with mortality , 2003, Annals of the rheumatic diseases.

[27]  J. Kaprio,et al.  Genetic and Environmental Factors in Complex Diseases: The Older Finnish Twin Cohort , 2002, Twin Research.

[28]  J. Loughlin,et al.  Association of the interleukin-1 gene cluster on chromosome 2q13 with knee osteoarthritis. , 2002, Arthritis and rheumatism.

[29]  R. Kastelein,et al.  Two Novel IL-1 Family Members, IL-1δ and IL-1ε, Function as an Antagonist and Agonist of NF-κB Activation Through the Orphan IL-1 Receptor-Related Protein 21 , 2001, The Journal of Immunology.

[30]  P. Donnelly,et al.  A new statistical method for haplotype reconstruction from population data. , 2001, American journal of human genetics.

[31]  J. Sieper,et al.  Association of genotypes affecting the expression of interleukin-1beta or interleukin-1 receptor antagonist with osteoarthritis. , 2000, Arthritis and rheumatism.

[32]  J. Sinsheimer,et al.  Linkage analysis of chromosome 2q in osteoarthritis. , 2000, Rheumatology.

[33]  H H Göring,et al.  Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. , 2000, American journal of human genetics.

[34]  L. Peltonen,et al.  Genome scan for predisposing loci for distal interphalangeal joint osteoarthritis: evidence for a locus on 2q. , 1999, American journal of human genetics.

[35]  L. Peltonen,et al.  Joint-specific twin and familial aggregation of recalled physician diagnosed osteoarthritis , 1999, Twin Research.

[36]  M. Sheppard,et al.  In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression. , 1999, The American journal of pathology.

[37]  J R O'Connell,et al.  PedCheck: a program for identification of genotype incompatibilities in linkage analysis. , 1998, American journal of human genetics.

[38]  L. O’Neill,et al.  Signal transduction pathways activated by the IL‐1 receptor family: ancient signaling machinery in mammals, insects, and plants , 1998, Journal of leukocyte biology.

[39]  C. Dinarello,et al.  Three distinct promoters direct transcription of different 5' untranslated regions of the human interleukin 1 type I receptor: a possible mechanism for control of translation. , 1996, Cytokine.

[40]  M. Doherty,et al.  Association of two loci on chromosome 2q with nodal osteoarthritis. , 1996, Annals of the rheumatic diseases.

[41]  T. Spector,et al.  Genetic influences on osteoarthritis in women: a twin study , 1996, BMJ.

[42]  C. Dinarello,et al.  Biologic basis for interleukin-1 in disease. , 1996, Blood.

[43]  R. Hirsch,et al.  Association of hand and knee osteoarthritis: evidence for a polyarticular disease subset. , 1996, Annals of the rheumatic diseases.

[44]  T. Spector,et al.  Defining osteoarthritis of the hand for epidemiological studies: the Chingford Study. , 1994, Annals of the rheumatic diseases.

[45]  J. Kellgren,et al.  Radiological Assessment of Osteo-Arthrosis , 1957, Annals of the rheumatic diseases.

[46]  J. Kellgren,et al.  Generalized Osteoarthritis and Heberden's Nodes , 1952, British medical journal.

[47]  S. Jimenez,et al.  NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis. , 2006, Osteoarthritis and cartilage.

[48]  N. Abels Merlin , 2005, Mittelalterrezeption im Musiktheater.

[49]  Pak Chung Sham,et al.  Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits , 2003, Bioinform..

[50]  G. Abecasis,et al.  Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.

[51]  R. Kastelein,et al.  Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. , 2001, Journal of immunology.

[52]  Wei Huang,et al.  Bmc Medical Genetics , 2022 .