1 INVOLVEMENT OF GLUTAREDOXIN-1 AND THIOREDOXIN-1 IN BETA AMYLOID TOXICITY AND ALZHEIMER ’ S DISEASE

1. Section of Experimental Geriatrics, Neurotec Department, Karolinska Institutet, Kliniskt Forskningscentrum (KFC), Novum, S-141 86 Huddinge, Sweden. 2. Department of Biosciences, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden. 3. Centro Andaluz de Biología del Desarrollo (CABD-CSIC), Departamento de Ciencias Ambientales, Universidad Pablo de Olavide, 41013 Sevilla, Spain. Running title: Glutaredoxin-1 and Thioredoxin-1 in Alzheimer’s Disease *Address correspondence to: Angel Cedazo-Minguez, PhD, Karolinska Institutet, Neurotec Department. Section of Experimental Geriatrics, Novum, KFC, plan 4. S-141 86 Huddinge, Sweden. Phone: +46 8 585 83751. Fax: +46 8 585 83880. E-mail: Angel.CedazoMinguez@neurotec.ki.se