Blood-brain barrier, considerations in drug development and delivery
暂无分享,去创建一个
[1] David S. Miller,et al. Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy , 2008, Pharmacological Reviews.
[2] Heidrun Potschka,et al. Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling , 2008, Molecular Pharmacology.
[3] Bill J Smith,et al. Progress in Brain Penetration Evaluation in Drug Discovery and Development , 2008, Journal of Pharmacology and Experimental Therapeutics.
[4] Kim Mouridsen,et al. MRI Detection of Early Blood-Brain Barrier Disruption: Parenchymal Enhancement Predicts Focal Hemorrhagic Transformation After Thrombolysis , 2008, Stroke.
[5] B. Zlokovic. The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders , 2008, Neuron.
[6] Anthony R. Calabria,et al. A Genomic Comparison of in vivo and in vitro Brain Microvascular Endothelial Cells , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[7] C. Iadecola,et al. Glial regulation of the cerebral microvasculature , 2007, Nature Neuroscience.
[8] W. Pardridge,et al. Intravenous siRNA of Brain Cancer with Receptor Targeting and Avidin–Biotin Technology , 2007, Pharmaceutical Research.
[9] E. Shusta,et al. Blood–Brain Barrier Transport of Therapeutics via Receptor-Mediation , 2007, Pharmaceutical Research.
[10] B. Davidson,et al. Transvascular delivery of small interfering RNA to the central nervous system , 2007, Nature.
[11] R. Boado. Blood–brain Barrier Transport of Non-viral Gene and RNAi Therapeutics , 2007, Pharmaceutical Research.
[12] W. Pardridge. Drug Targeting to the Brain , 2007, Pharmaceutical Research.
[13] E. Gerstner,et al. Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigm. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] I. Verma,et al. Targeted delivery of proteins across the blood–brain barrier , 2007, Proceedings of the National Academy of Sciences.
[15] Shuzhen Guo,et al. Cell–cell Signaling in the Neurovascular Unit , 2007, Neurochemical Research.
[16] Stephen L. Brown,et al. Relative distribution of plasma flow markers and red blood cells across BBB openings in acute cerebral ischemia , 2007, Neurological research.
[17] S. Hitchcock,et al. Structure-brain exposure relationships. , 2006, Journal of medicinal chemistry.
[18] R. Bendayan,et al. Multidrug Resistance-Associated Proteins: Expression and Function in the Central Nervous System , 2006, Pharmacological Reviews.
[19] E. Kılıç,et al. Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia , 2006, Nature Neuroscience.
[20] E. Hamel. Perivascular nerves and the regulation of cerebrovascular tone. , 2006, Journal of applied physiology.
[21] Andreas Reichel,et al. The role of blood-brain barrier studies in the pharmaceutical industry. , 2006, Current drug metabolism.
[22] Wolfgang Löscher,et al. Drug resistance in brain diseases and the role of drug efflux transporters , 2005, Nature Reviews Neuroscience.
[23] T. Davis,et al. The Blood-Brain Barrier/Neurovascular Unit in Health and Disease , 2005, Pharmacological Reviews.
[24] N. Abbott. Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation , 2005, Cellular and Molecular Neurobiology.
[25] D. Begley. Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. , 2004, Pharmacology & therapeutics.
[26] C. Borlongan,et al. Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport , 2003, Brain Research Bulletin.
[27] E. Neuwelt,et al. Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. , 1998, Neurosurgery.
[28] M. Wiley,et al. Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail--chick transplantation chimeras. , 1981, Developmental biology.
[29] U. Bickel,et al. How to measure drug transport across the blood-brain barrier , 2011, NeuroRX.
[30] R. Egleton,et al. Pathophysiology of the blood-brain barrier: animal models and methods. , 2008, Current topics in developmental biology.
[31] V. Perry,et al. What is the blood-brain barrier (not)? , 2007, Trends in immunology.
[32] E. Hansson,et al. Astrocyte–endothelial interactions at the blood–brain barrier , 2006, Nature Reviews Neuroscience.
[33] A. Schinkel. The roles of P-glycoprotein and MRP1 in the blood-brain and blood-cerebrospinal fluid barriers. , 2001, Advances in experimental medicine and biology.