The influence of anesthetic choice on carotid endarterectomy outcome.

This study compared the technique of general and regional cervical block anesthesia for carotid endarterectomy. Three hundred sixty-eight patients undergoing 399 carotid endarterectomies were administered one of these alternative anesthetics as selected preoperatively by each patient and his or her physician. In 242 cases general anesthesia was used. The other 157 cases were done under regional cervical block anesthesia. Perioperative mortality was 1.0%. Nonfatal strokes occurred in 1.25%. There were significantly more strokes in the general anesthesia group. Perioperative blood pressure was unstable for a significantly longer period of time after general anesthesia (mean, 24.6 hours) as compared with regional cervical block anesthesia (mean, 2.1 hours). Furthermore, vasoactive drugs were required for significantly longer periods of time in the general anesthesia group.

[1]  M. Mcgregor,et al.  BIOSTATISTICS IN CLINICAL MEDICINE. , 1987 .

[2]  R. Berguer,et al.  The silent brain infarct in carotid surgery. , 1986, Journal of vascular surgery.

[3]  E. Waltke,et al.  Optimal cerebral monitoring during carotid endarterectomy: neurologic response under local anesthesia. , 1985, Journal of vascular surgery.

[4]  J. Adriani,et al.  Labat's Regional Anesthesia: Techniques and Clinical Applications , 1985 .

[5]  A. Whittemore,et al.  Early carotid endarterectomy in patients with small, fixed neurologic deficits. , 1984, Journal of vascular surgery.

[6]  A. Callow Recurrent stenosis after carotid endarterectomy. , 1982, Archives of surgery.

[7]  F W Sharbrough,et al.  Correlation of cerebral blood flow and electroencephalographic changes during carotid endarterectomy: with results of surgery and hemodynamics of cerebral ischemia. , 1981, Mayo Clinic proceedings.

[8]  Towne Jb,et al.  The relationship of postoperative hypertension to complications following carotid endarterectomy. , 1980 .

[9]  D. Cooley,et al.  Carotid Endarterectomy Without Temporary Intraluminal Shunt Study of 309 Consecutive Operations , 1980, Annals of surgery.

[10]  T. Riles,et al.  Carotid artery stenosis with contralateral internal carotid occlusion: long-term results in fifty-four patients. , 1980, Surgery.

[11]  J. Kelly,et al.  Failure of carotid stump pressures. Its incidence as a predictor for a temporary shunt during carotid endarterectomy. , 1979, Archives of surgery.

[12]  R. M. Scott,et al.  Carotid endarterectomy in the presence of contralateral carotid occlusion: the role of EEG and intraluminal shunting. , 1979, Archives of surgery.

[13]  E. Stemmer,et al.  Improved Results with Carotid Endarterectomy , 1977, Annals of surgery.

[14]  W. Moore,et al.  Emergency carotid artery surgery in neurologically unstable patients. , 1976, Archives of surgery.

[15]  C. W. Watson,et al.  An evaluation of electroencephalographic monitoring for carotid study. , 1975, Surgery.

[16]  R. Hobson,et al.  Carotid artery back pressure and endarterectomy under regional anesthesia. , 1974, Archives of surgery.

[17]  A. D. Hall,et al.  Collateral cerebral blood pressure. An index of tolerance to temporary carotid occlusion. , 1973 .

[18]  E. Wylie,et al.  Intraoperative measurement of carotid back pressure as a guide to operative management for carotid endarterectomy. , 1972, Surgery.

[19]  J. Severinghaus,et al.  Effect of CO2 and systemic hypertension on downstream cerebral arterial pressure during carotid endarterectomy. , 1971, Surgery.

[20]  S. Alexander,et al.  Cerebral Circulatory Response to Acute Brain Disease: Implications for Anesthetic Practice , 1970, Anesthesiology.

[21]  A. G. Waltz Effect of blood pressure on blood flow in ischemic and in nonischemic cerebral cortex , 1968, Neurology.

[22]  D. Cooley,et al.  Carotid endarterectomy without a shunt. Results using hypercarbic general anesthesia to prevent cerebral ischemia. , 1968, Archives of surgery.

[23]  J. A. Bain,et al.  The effect of general anaesthesia on the tolerance of cerebral ischaemia in rabbits , 1967, Canadian Anaesthetists' Society journal.

[24]  J. A. Gillespie,et al.  Management of carotid endarterectomy with special reference to anaesthesia , 1963, The British journal of surgery.

[25]  D. Cooley,et al.  Increased tolerance to cerebral ischemia produced by general anesthesia during temporary carotid occlusion. , 1963, Surgery.

[26]  De Bakey Me,et al.  Hemodynamic alterations in patients with cerebral arterial insufficiency before and after operation. , 1960, Surgery.

[27]  G W PICKERING,et al.  Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia. , 1954, Lancet.

[28]  G. Boysen Cerebral hemodynamics in carotid surgery. , 1973, Acta neurologica Scandinavica. Supplementum.

[29]  W. Ehrenfeld,et al.  Extracranial occlusive cerebrovascular disease;: Diagnosis and management , 1970 .