Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles.
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[1] M. Hranjec,et al. Novel amidino-substituted benzimidazoles: synthesis of compounds and inhibition of dipeptidyl peptidase III. , 2007, Bioorganic chemistry.
[2] Mohamed A. Omar,et al. Synthesis and antitumor activity of 1-substituted-2-methyl-5-nitrobenzimidazoles. , 2006, Bioorganic & medicinal chemistry.
[3] K. Biron. Antiviral drugs for cytomegalovirus diseases. , 2006, Antiviral research.
[4] K. Pavelić,et al. Synthesis, photochemical synthesis, DNA binding and antitumor evaluation of novel cyano- and amidino-substituted derivatives of naphtho-furans, naphtho-thiophenes, thieno-benzofurans, benzo-dithiophenes and their acyclic precursors. , 2006, European journal of medicinal chemistry.
[5] Satoru Ikeda,et al. Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109. , 2006, Journal of medicinal chemistry.
[6] Jian-Ping Zuo,et al. Synthesis and anti-hepatitis B virus activity of novel benzimidazole derivatives. , 2006, Journal of medicinal chemistry.
[7] P. A. Ropp,et al. Effects of coordinating metal ions on the mediated inhibition of trypsin by bis(benzimidazoles) and related compounds. , 2006, Inorganic chemistry.
[8] J. Janc,et al. Generation of potent coagulation protease inhibitors utilizing zinc-mediated chelation. , 2006, Bioorganic & medicinal chemistry letters.
[9] W. Wilson,et al. Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents. , 2005, Bioorganic & medicinal chemistry.
[10] D. Boykin,et al. Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines. , 2005, European journal of medicinal chemistry.
[11] A. Mavrova,et al. Synthesis and antitrichinellosis activity of some 2-substituted-[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-ones. , 2005, Bioorganic & medicinal chemistry.
[12] Mercedes González,et al. Imidazole and benzimidazole derivatives as chemotherapeutic agents. , 2005, Mini reviews in medicinal chemistry.
[13] D. Boykin,et al. Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles. , 2005, Bioorganic & medicinal chemistry.
[14] S. Yıldız,et al. Synthesis and potent antimicrobial activity of some novel methyl or ethyl 1H-benzimidazole-5-carboxylates derivatives carrying amide or amidine groups. , 2005, Bioorganic & medicinal chemistry.
[15] Jiangtao Xie,et al. Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives. , 2005, Bioorganic & medicinal chemistry letters.
[16] R. Ptak,et al. Inhibition of Human Cytomegalovirus Replication by Benzimidazole Nucleosides Involves Three Distinct Mechanisms , 2004, Antimicrobial Agents and Chemotherapy.
[17] Hua Tang,et al. Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles. , 2004, Antiviral research.
[18] F. Diederich,et al. Structure‐Based Design, Synthesis, and in vitro Evaluation of Nonpeptidic Neprilysin Inhibitors , 2004, Chembiochem : a European journal of chemical biology.
[19] C. Bailly,et al. Mechanistic and anti-proliferative studies of two novel, biologically active bis-benzimidazoles. , 2003, European journal of cancer.
[20] M. Osmak,et al. Tumor cytosol dipeptidyl peptidase III activity is increased with histological aggressiveness of ovarian primary carcinomas. , 2003, Gynecologic oncology.
[21] E. Kern,et al. In Vitro Activities of Benzimidazole d- and l-Ribonucleosides against Herpesviruses , 2003, Antimicrobial Agents and Chemotherapy.
[22] L. Yépez-Mulia,et al. Synthesis, antiprotozoal and anticancer activity of substituted 2-trifluoromethyl- and 2-pentafluoroethylbenzimidazoles. , 2002, European journal of medicinal chemistry.
[23] D. Smee,et al. Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds. , 2002, Journal of virological methods.
[24] Jack A Roth,et al. Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[25] D. V. Von Hoff,et al. Preclinical Antitumor Activity and Pharmacokinetics of Methyl-2-Benzimidazolecarbamate (FB642) , 2002, Investigational New Drugs.
[26] S. Yıldız,et al. Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species. , 2002, Bioorganic & medicinal chemistry.
[27] M. Hranjec,et al. New amidino-benzimidazolyl derivatives of tylosin and desmycosin. , 2002, The Journal of antibiotics.
[28] B. Foleno,et al. Amidino benzimidazole inhibitors of bacterial two-component systems. , 2001, Bioorganic & medicinal chemistry letters.
[29] C. Cermelli,et al. Antiviral and antiproliferative activity in vitro of some new benzimidazole derivatives. , 2001, Pharmacology & toxicology.
[30] I. Islam,et al. Structure-activity studies of benzimidazole-based DNA-cleaving agents. Comparison of benzimidazole, pyrrolobenzimidazole, and tetrahydropyridobenzimidazole analogues. , 1994, Journal of medicinal chemistry.
[31] W. Denny,et al. Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II. , 1990, Journal of medicinal chemistry.
[32] E. Dubovi,et al. Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin. , 1983, Journal of medicinal chemistry.
[33] D. Neilson,et al. The Chemistry of Imidates. , 1961 .
[34] K. Pavelić,et al. Novel cyano- and N-isopropylamidino-substituted derivatives of benzo[b]thiophene-2-carboxanilides and benzo[b]thieno[2,3-c]quinolones: synthesis, photochemical synthesis, crystal structure determination, and antitumor evaluation. 2. , 2005, Journal of medicinal chemistry.
[35] M. Grce,et al. Novel 1,2,5-oxadiazine derivatives--synthesis and in vitro biological studies. , 2003, Acta pharmaceutica.
[36] G. Karminski-Zamola,,et al. NEW AMIDINO-SUBSTITUTED BENZIMIDAZOLYL FURYL-THIENYL-ACRYLATES AND BENZOTHIENOFURANS; SYNTHESIS AND PHOTOCHEMICAL SYNTHESIS , 2002 .
[37] Satyavan Sharma,et al. 2-Aminobenzimidazoles in Organic Syntheses , 1983 .