A computational modeling and molecular dynamics study of the Michaelis complex of human protein Z-dependent protease inhibitor (ZPI) and factor Xa (FXa)
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L. Pedersen | R. Duke | C. Lee | V. Chandrasekaran | P. Lin
[1] J. Bae,et al. Protein Z-dependent Protease Inhibitor Binds to the C-terminal Domain of Protein Z* , 2008, Journal of Biological Chemistry.
[2] D. Case,et al. Homology Modeling of NR2B Modulatory Domain of NMDA Receptor and Analysis of Ifenprodil Binding , 2007, ChemMedChem.
[3] J. C. Rau,et al. Serpins in thrombosis, hemostasis and fibrinolysis , 2007, Journal of thrombosis and haemostasis : JTH.
[4] L. Pedersen,et al. A proposed structural model of human protein Z , 2007, Journal of thrombosis and haemostasis : JTH.
[5] B. Olgemöller,et al. Hybridization probe genotyping of the R67X nonsense polymorphism in the protein Z-dependent protease inhibitor reveals a new R67Q mutation. , 2007, Clinical chemistry.
[6] Steven W. Muchmore,et al. Rapid Estimation of Relative Protein-Ligand Binding Affinities Using a High-Throughput Version of MM-PBSA , 2007, J. Chem. Inf. Model..
[7] J. Corral,et al. Protein Z/Z‐dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis , 2007, British journal of haematology.
[8] A. Folsom,et al. Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism , 2007, Thrombosis and Haemostasis.
[9] G. Damante,et al. Mutations R67X and W303X of the protein Z-dependent protease inhibitor gene and venous thromboembolic disease: a case–control study in Italian subjects , 2007, Journal of Thrombosis and Thrombolysis.
[10] J. Whisstock,et al. An overview of the serpin superfamily , 2006, Genome Biology.
[11] J. Huntington,et al. Antithrombin–S195A factor Xa‐heparin structure reveals the allosteric mechanism of antithrombin activation , 2006, The EMBO journal.
[12] I. Martinelli,et al. Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism , 2006, Thrombosis and Haemostasis.
[13] Martin Almlöf,et al. Probing the effect of point mutations at protein-protein interfaces with free energy calculations. , 2006, Biophysical journal.
[14] A. Kornberg,et al. Protein Z levels and central retinal vein or artery occlusion , 2005, European journal of haematology.
[15] K. M. Cabral,et al. Down-regulation of Factor IXa in the Factor Xase Complex by Protein Z-dependent Protease Inhibitor* , 2005, Journal of Biological Chemistry.
[16] A. Rezaie,et al. Identification of Factor Xa Residues Critical for Interaction with Protein Z-dependent Protease Inhibitor , 2005, Journal of Biological Chemistry.
[17] R. Eckert,et al. Reformable intramolecular cross-linking of the N-terminal domain of heparin cofactor II: effects on enzyme inhibition. , 2004, European journal of biochemistry.
[18] P. Browett,et al. Mutations within the protein Z‐dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia , 2004, British journal of haematology.
[19] C. Esmon,et al. Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism of heparin , 2004, Nature Structural &Molecular Biology.
[20] Lisa D. Cabrita,et al. How do proteins avoid becoming too stable? Biophysical studies into metastable proteins , 2004, European Biophysics Journal.
[21] S. Olson,et al. Serpin-ligand interactions. , 2004, Methods.
[22] Holger Gohlke,et al. Converging free energy estimates: MM‐PB(GB)SA studies on the protein–protein complex Ras–Raf , 2004, J. Comput. Chem..
[23] P. Gettins. Serpin structure, mechanism, and function. , 2002, Chemical reviews.
[24] A. Paganini-Hill,et al. Low protein Z levels and risk of ischemic stroke: differences by diabetic status and gender. , 2002, Blood cells, molecules & diseases.
[25] R. Carrell,et al. Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[26] B. Lämmle,et al. Frequency of protein Z deficiency in patients with ischaemic stroke , 2001, The Lancet.
[27] G. Broze. Protein Z-Dependent Regulation of Coagulation , 2001, Thrombosis and Haemostasis.
[28] G. Broze,et al. Protein Z Circulates in Plasma in a Complex with Protein Z-Dependent Protease Inhibitor , 2001, Thrombosis and Haemostasis.
[29] X. Han,et al. Characterization of the protein Z-dependent protease inhibitor. , 2000, Blood.
[30] J. Whisstock,et al. Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin. , 2000, Journal of molecular biology.
[31] A. Rezaie. Identification of Basic Residues in the Heparin-binding Exosite of Factor Xa Critical for Heparin and Factor Va Binding* , 2000, The Journal of Biological Chemistry.
[32] X. Han,et al. The protein Z-dependent protease inhibitor is a serpin. , 1999, Biochemistry.
[33] Xiongwu Wu,et al. Self-Guided Molecular Dynamics Simulation for Efficient Conformational Search , 1998 .
[34] M. Sternberg,et al. Modelling protein docking using shape complementarity, electrostatics and biochemical information. , 1997, Journal of molecular biology.
[35] J. Whisstock,et al. The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. , 1997, Journal of molecular biology.
[36] T. Darden,et al. A smooth particle mesh Ewald method , 1995 .
[37] J. Thompson,et al. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.
[38] T. Blundell,et al. Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.
[39] T. Darden,et al. Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .
[40] J. Thornton,et al. PROCHECK: a program to check the stereochemical quality of protein structures , 1993 .
[41] D. Eisenberg,et al. Assessment of protein models with three-dimensional profiles , 1992, Nature.
[42] D. Tollefsen,et al. The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans. , 1991, The Journal of biological chemistry.
[43] H. Ragg,et al. Glycosaminoglycan-mediated leuserpin-2/thrombin interaction. Structure-function relationships. , 1990, The Journal of biological chemistry.
[44] J. Tainer,et al. Elucidating the structural chemistry of glycosaminoglycan recognition by protein C inhibitor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[45] W. L. Jorgensen,et al. Comparison of simple potential functions for simulating liquid water , 1983 .
[46] M. Karplus,et al. CHARMM: A program for macromolecular energy, minimization, and dynamics calculations , 1983 .
[47] D. Lomas,et al. Topography of a 2.0 Å structure of α1‐antitrypsin reveals targets for rational drug design to prevent conformational disease , 2000, Protein science : a publication of the Protein Society.
[48] P A Kollman,et al. Continuum solvent studies of the stability of RNA hairpin loops and helices. , 1998, Journal of biomolecular structure & dynamics.
[49] Rolf Apweiler,et al. The SWISS-PROT protein sequence data bank and its supplement TrEMBL , 1997, Nucleic Acids Res..
[50] D. Eisenberg,et al. A method to identify protein sequences that fold into a known three-dimensional structure. , 1991, Science.
[51] M. Caron,et al. Structure-Function Relationships , 1991 .
[52] J. Miletich,et al. Human plasma protein Z antigen: range in normal subjects and effect of warfarin therapy. , 1987, Blood.