Reiterated Wnt and BMP signals in neural crest development.

[1]  M. Khokha,et al.  Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. , 2005, Developmental cell.

[2]  P. S. Klein,et al.  Neural crest induction by the canonical Wnt pathway can be dissociated from anterior-posterior neural patterning in Xenopus. , 2005, Developmental biology.

[3]  R. Harland,et al.  Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction. , 2005, Developmental cell.

[4]  Christina R. Evola,et al.  Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction. , 2005, Developmental biology.

[5]  A. Bejsovec Wnt Pathway Activation New Relations and Locations , 2005, Cell.

[6]  J. W. Ragland,et al.  Signals derived from the underlying mesoderm are dispensable for zebrafish neural crest induction. , 2004, Developmental biology.

[7]  D. Wilkinson,et al.  A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration , 2004, Development.

[8]  T. Burstyn-Cohen,et al.  Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition , 2004, Development.

[9]  R. Nusse,et al.  The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.

[10]  W. Pavan,et al.  WNT1 and WNT3a promote expansion of melanocytes through distinct modes of action. , 2004, Pigment cell research.

[11]  W. Pavan,et al.  Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf. , 2004, Pigment cell research.

[12]  A. D. de Melker,et al.  Cellular localization and signaling activity of β‐catenin in migrating neural crest cells , 2004 .

[13]  Stephen W. Wilson,et al.  Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains , 2004, Development.

[14]  J. Epstein,et al.  Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells , 2004, Development.

[15]  J. Klingensmith,et al.  BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium , 2004, Development.

[16]  T. P. Rothman,et al.  Bone Morphogenetic Protein-2 and -4 Limit the Number of Enteric Neurons But Promote Development of a TrkC-Expressing Neurotrophin-3-Dependent Subset , 2004, The Journal of Neuroscience.

[17]  J. W. Ragland,et al.  Reiterated Wnt signaling during zebrafish neural crest development , 2004, Development.

[18]  P. Knaus,et al.  Signal transduction of bone morphogenetic protein receptors. , 2004, Cellular signalling.

[19]  U. Suter,et al.  Instructive Role of Wnt/ß-Catenin in Sensory Fate Specification in Neural Crest Stem Cells , 2004, Science.

[20]  V. Kaartinen,et al.  Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells , 2004, Mechanisms of Development.

[21]  A. Tucker,et al.  Fgf and Bmp signals repress the expression of Bapx1 in the mandibular mesenchyme and control the position of the developing jaw joint. , 2004, Developmental biology.

[22]  M. Wegner,et al.  Melanocyte‐specific expression of dopachrome tautomerase is dependent on synergistic gene activation by the Sox10 and Mitf transcription factors , 2004, FEBS letters.

[23]  P. Kulesa,et al.  Comparative analysis of neural crest cell death, migration, and function during vertebrate embryogenesis , 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

[24]  R. Mayor,et al.  Identification of neural crest competence territory: Role of Wnt signaling , 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

[25]  Manuel J. Aybar,et al.  Regulation of Msx genes by a Bmp gradient is essential for neural crest specification , 2003, Development.

[26]  E. D. De Robertis,et al.  Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. , 2003, Genes & development.

[27]  Manuel J. Aybar,et al.  Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos , 2003, Development.

[28]  E. Price,et al.  A Tissue-restricted cAMP Transcriptional Response , 2003, Journal of Biological Chemistry.

[29]  E. Dupin,et al.  Multipotentiality of the neural crest. , 2003, Current opinion in genetics & development.

[30]  Manuel J. Aybar,et al.  Sox10 is required for the early development of the prospective neural crest in Xenopus embryos. , 2003, Developmental biology.

[31]  Russell B. Fletcher,et al.  Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals , 2003, Development.

[32]  J. Saint-Jeannet,et al.  Sox10 regulates the development of neural crest-derived melanocytes in Xenopus. , 2003, Developmental biology.

[33]  R. Kelsh,et al.  Transcriptional regulation of mitfa accounts for the sox10 requirement in zebrafish melanophore development , 2003, Development.

[34]  David J. Anderson,et al.  SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells , 2003, Neuron.

[35]  U. Suter,et al.  Lineage-specific requirements of β-catenin in neural crest development , 2002, The Journal of cell biology.

[36]  P. Gallagher,et al.  Glia Induce Dendritic Growth in Cultured Sympathetic Neurons by Modulating the Balance between Bone Morphogenetic Proteins (BMPs) and BMP Antagonists , 2002, The Journal of Neuroscience.

[37]  L. Jerome-Majewska,et al.  Aortic arch and pharyngeal phenotype in the absence of BMP-dependent neural crest in the mouse , 2002, Mechanisms of Development.

[38]  U. Suter,et al.  Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease. , 2002, Human molecular genetics.

[39]  A. Tucker,et al.  Apoptosis of premigratory neural crest cells in rhombomeres 3 and 5: consequences for patterning of the branchial region. , 2002, Developmental biology.

[40]  W. Van Hul,et al.  Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. , 2002, Developmental biology.

[41]  S. Carroll,et al.  Molecular mechanisms of selector gene function and evolution. , 2002, Current opinion in genetics & development.

[42]  K. Fu,et al.  Endogenous bone morphogenetic proteins regulate outgrowth and epithelial survival during avian lip fusion. , 2002, Development.

[43]  E. Price,et al.  β-Catenin–induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor , 2002, The Journal of Cell Biology.

[44]  Stephen W. Wilson,et al.  Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. , 2002, Development.

[45]  T. Burstyn-Cohen,et al.  Association between the cell cycle and neural crest delamination through specific regulation of G1/S transition. , 2002, Developmental cell.

[46]  S. Morrison,et al.  Neural Crest Stem Cells Persist in the Adult Gut but Undergo Changes in Self-Renewal, Neuronal Subtype Potential, and Factor Responsiveness , 2002, Neuron.

[47]  C. Marcelle,et al.  Ectodermal Wnt Function as a Neural Crest Inducer , 2002, Science.

[48]  Manuel J. Aybar,et al.  Early induction of neural crest cells: lessons learned from frog, fish and chick. , 2002, Current opinion in genetics & development.

[49]  Kazuhiro Takahashi,et al.  Identification of a distal enhancer for the melanocyte-specific promoter of the MITF gene. , 2002, Pigment cell research.

[50]  J. Eisen,et al.  Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function. , 2002, Development.

[51]  Andrew P McMahon,et al.  A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. , 2002, Development.

[52]  D. Roberts,et al.  Endogenous patterns of BMP signaling during early chick development. , 2002, Developmental biology.

[53]  Mina Mina,et al.  Region‐ and stage‐specific effects of FGFs and BMPs in chick mandibular morphogenesis , 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

[54]  Yukinori Endo,et al.  Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development. , 2002, Development.

[55]  R. Mayor,et al.  Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction. , 2002, Developmental biology.

[56]  K. Fu,et al.  Noggin and retinoic acid transform the identity of avian facial prominences , 2001, Nature.

[57]  J. Klingensmith,et al.  The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth. , 2001, Developmental biology.

[58]  C. Niehrs,et al.  A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. , 2001, Development.

[59]  R. Kelsh,et al.  Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates. , 2001, Development.

[60]  M. Wegner,et al.  Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling. , 2001, Development.

[61]  M. Deardorff,et al.  A role for frizzled 3 in neural crest development. , 2001, Development.

[62]  M. Deardorff,et al.  Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development. , 2001, Development.

[63]  C. Wright,et al.  Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo. , 2001, Development.

[64]  W. Gomes,et al.  Msx-2 and p21 mediate the pro-apoptotic but not the anti-proliferative effects of BMP4 on cultured sympathetic neuroblasts. , 2001, Developmental biology.

[65]  R. Moon,et al.  Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning. , 2001, Developmental cell.

[66]  M. Goossens,et al.  Loss-of-function mutations in SIP1 Smad interacting protein 1 result in a syndromic Hirschsprung disease. , 2001, Human molecular genetics.

[67]  F. Verbeek,et al.  Misexpression of noggin leads to septal defects in the outflow tract of the chick heart. , 2001, Developmental biology.

[68]  S. Takada,et al.  Wnt and BMP signaling govern lineage segregation of melanocytes in the avian embryo. , 2001, Developmental biology.

[69]  S. Carroll,et al.  Control of a Genetic Regulatory Network by a Selector Gene , 2001, Science.

[70]  N. Nomura,et al.  Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease , 2001, Nature Genetics.

[71]  A. Graham,et al.  Restricting Bmp‐4 mediated apoptosis in hindbrain neural crest , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[72]  R. Ballotti,et al.  Direct Regulation of the Microphthalmia Promoter by Sox10 Links Waardenburg-Shah Syndrome (WS4)-associated Hypopigmentation and Deafness to WS2* , 2000, The Journal of Biological Chemistry.

[73]  D. Sela-Donenfeld,et al.  Inhibition of noggin expression in the dorsal neural tube by somitogenesis: a mechanism for coordinating the timing of neural crest emigration. , 2000, Development.

[74]  S. Birren,et al.  Postmigratory enteric and sympathetic neural precursors share common, developmentally regulated, responses to BMP2. , 2000, Developmental biology.

[75]  K. Bille,et al.  Regulation of the Microphthalmia-associated Transcription Factor Gene by the Waardenburg Syndrome Type 4 Gene,SOX10 * , 2000, The Journal of Biological Chemistry.

[76]  Yoichi Kato,et al.  LDL-receptor-related proteins in Wnt signal transduction , 2000, Nature.

[77]  H. Rohrer,et al.  The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification. , 2000, Development.

[78]  M. Wegner,et al.  Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome. , 2000, Human molecular genetics.

[79]  A. Streit,et al.  Initiation of neural induction by FGF signalling before gastrulation , 2000, Nature.

[80]  J. Eisen,et al.  Delta signaling mediates segregation of neural crest and spinal sensory neurons from zebrafish lateral neural plate. , 2000, Development.

[81]  W. Pavan,et al.  Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3 , 2000, Human Genetics.

[82]  Kazuhiro Takahashi,et al.  Induction of Melanocyte-specific Microphthalmia-associated Transcription Factor by Wnt-3a* , 2000, The Journal of Biological Chemistry.

[83]  C. McPherson,et al.  Expression and regulation of type I BMP receptors during early avian sympathetic ganglion development. , 2000, Developmental biology.

[84]  A. McMahon,et al.  Fate of the mammalian cardiac neural crest. , 2000, Development.

[85]  E. Weinberg,et al.  Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway. , 2000, Development.

[86]  W. Talbot,et al.  Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. , 2000, Development.

[87]  D. Raible,et al.  Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. , 2000, Genes & development.

[88]  M. Wegner,et al.  Bone Morphogenetic Proteins Are Required In Vivo for the Generation of Sympathetic Neurons , 1999, Neuron.

[89]  Chaya Kalcheim,et al.  The Neural Crest: Author Index , 1999 .

[90]  S. Wilson,et al.  Bmp activity establishes a gradient of positional information throughout the entire neural plate. , 1999, Development.

[91]  D. Sela-Donenfeld,et al.  Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube. , 1999, Development.

[92]  A. Fainsod,et al.  Patterning of the mesoderm involves several threshold responses to BMP-4 and Xwnt-8 , 1999, Mechanisms of Development.

[93]  Stephen L. Johnson,et al.  nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate. , 1999, Development.

[94]  D. Newgreen,et al.  A paraxial exclusion zone creates patterned cranial neural crest cell outgrowth adjacent to rhombomeres 3 and 5. , 1999, Developmental biology.

[95]  M. Goulding,et al.  Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm. , 1999, Developmental biology.

[96]  S. Birren,et al.  Restriction of developmental potential during divergence of the enteric and sympathetic neuronal lineages. , 1999, Development.

[97]  T. Bouwmeester,et al.  The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo. , 1999, Development.

[98]  E. Robertson,et al.  Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. , 1999, Development.

[99]  D. Rimm,et al.  Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. , 1999, The American journal of pathology.

[100]  K. Artinger,et al.  Effects of Shh and Noggin on neural crest formation demonstrate that BMP is required in the neural tube but not ectoderm. , 1998, Development.

[101]  Randall T. Moon,et al.  Control of neural crest cell fate by the Wnt signalling pathway , 1998, Nature.

[102]  M. Ekker,et al.  Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. , 1998, Developmental biology.

[103]  M. Bronner‐Fraser,et al.  Neural crest induction in Xenopus: evidence for a two-signal model. , 1998, Development.

[104]  R. Mayor,et al.  The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient. , 1998, Developmental biology.

[105]  M. Mehler,et al.  Development of Bone Morphogenetic Protein Receptors in the Nervous System and Possible Roles in Regulating trkC Expression , 1998, The Journal of Neuroscience.

[106]  Katsu Takahashi,et al.  Adenovirus-mediated ectopic expression of Msx2 in even-numbered rhombomeres induces apoptotic elimination of cranial neural crest cells in ovo. , 1998, Development.

[107]  M. Wegner,et al.  Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[108]  M. Mochii,et al.  Spontaneous transdifferentiation of quail pigmented epithelial cell is accompanied by a mutation in the Mitf gene. , 1998, Developmental biology.

[109]  D. Higgins,et al.  Osteogenic protein-1 and related bone morphogenetic proteins regulate dendritic growth and the expression of microtubule-associated protein-2 in rat sympathetic neurons , 1998, Neuroscience Letters.

[110]  L. Niswander,et al.  Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures. , 1998, Developmental biology.

[111]  M. Mehler,et al.  Bone morphogenetic proteins induce apoptosis and growth factor dependence of cultured sympathoadrenal progenitor cells. , 1998, Developmental biology.

[112]  R. Moon,et al.  BMP-2/-4 and Wnt-8 cooperatively pattern the Xenopus mesoderm , 1998, Mechanisms of Development.

[113]  M. Wegner,et al.  Sox10, a Novel Transcriptional Modulator in Glial Cells , 1998, The Journal of Neuroscience.

[114]  H. Varmus,et al.  Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[115]  M. Bronner‐Fraser,et al.  The origins of the neural crest. Part I: embryonic induction , 1997, Mechanisms of Development.

[116]  R. Moon,et al.  Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus , 1997, Mechanisms of Development.

[117]  A. McMahon,et al.  Wnt signalling required for expansion of neural crest and CNS progenitors , 1997, Nature.

[118]  R. Mayor,et al.  Role of FGF and noggin in neural crest induction. , 1997, Developmental biology.

[119]  D. Sassoon,et al.  Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway. , 1997, Developmental biology.

[120]  D. Maier,et al.  Xwnt-8 and lithium can act upon either dorsal mesodermal or neurectodermal cells to cause a loss of forebrain in Xenopus embryos. , 1997, Developmental biology.

[121]  M. Goulding,et al.  Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm. , 1997, Development.

[122]  T. Sadler,et al.  Disruption of Msx‐1 and Msx‐2 reveals roles for these genes in craniofacial, eye, and axial development , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

[123]  Paul Polakis,et al.  Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines , 1997, Science.

[124]  B. Hall,et al.  The in vivo and in vitro effects of bone morphogenetic protein-2 on the development of the chick mandible. , 1997, The International journal of developmental biology.

[125]  P. Francis-West,et al.  Ectopic application of recombinant BMP-2 and BMP-4 can change patterning of developing chick facial primordia. , 1997, Development.

[126]  S. Aaronson,et al.  Alkaptonuria: such a long journey , 1996, Nature Genetics.

[127]  R. Harland,et al.  The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4 , 1996, Cell.

[128]  H. Rohrer,et al.  Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons. , 1996, Development.

[129]  G. D. Maxwell,et al.  BMP-2 and BMP-4, but Not BMP-6, Increase the Number of Adrenergic Cells Which Develop in Quail Trunk Neural Crest Cultures , 1996, Experimental Neurology.

[130]  David J. Anderson,et al.  Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members , 1996, Cell.

[131]  R. Moon,et al.  Specification of the anteroposterior neural axis through synergistic interaction of the Wnt signaling cascade with noggin and follistatin. , 1995, Developmental biology.

[132]  T. Jessell,et al.  Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm , 1995, Cell.

[133]  D. Rueger,et al.  Number of adrenergic and Islet‐1 immunoreactive cells is increased in avian trunk neural crest cultures in the presence of human recombinant osteogenic protein‐1 , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[134]  M. Kirby,et al.  Neural crest and cardiovascular patterning. , 1995, Circulation research.

[135]  M. Dickinson,et al.  Dorsalization of the neural tube by the non-neural ectoderm. , 1995, Development.

[136]  R. Mayor,et al.  Induction of the prospective neural crest of Xenopus. , 1995, Development.

[137]  M. Bronner‐Fraser,et al.  Origins of the avian neural crest: the role of neural plate-epidermal interactions. , 1995, Development.

[138]  A. Graham,et al.  The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest , 1994, Nature.

[139]  R. Maas,et al.  Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development , 1994, Nature Genetics.

[140]  C. Kimmel,et al.  Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo. , 1994, Development.

[141]  N. Jenkins,et al.  Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein , 1993, Cell.

[142]  A. Jacobson,et al.  Neural fold formation at newly created boundaries between neural plate and epidermis in the axolotl. , 1989, Developmental biology.

[143]  K. Nave,et al.  The transcription factor Sox10 is a key regulator of peripheral glial development. , 2001, Genes & development.

[144]  W. Pavan,et al.  SOX10 mutation disrupts neural crest development in Dom Hirschsprung mouse model , 1998, Nature Genetics.

[145]  K. Kurihara,et al.  Bone morphogenetic protein-2 and retinoic acid induce neurotrophin-3 responsiveness in developing rat sympathetic neurons. , 1998, Brain research. Molecular brain research.

[146]  R. Moon,et al.  Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. , 1993, Genes & development.