A new asymmetric synthetic route to substituted piperidines

[1]  K. Nicolaou,et al.  Metathesis reactions in total synthesis. , 2005, Angewandte Chemie.

[2]  K. R. Rao,et al.  A mild and efficient synthesis of α-tosylamino ketones from aryl aziridines in the presence of β-cyclodextrin and NBS in water , 2005 .

[3]  T. Chakraborty,et al.  Synthesis of (3R,4S,5S,9S)-3,5,9-trihydroxy-4-methylundecanoic acid δ-lactone , 2004 .

[4]  K. R. Rao,et al.  Synthesis of Thiiranes from Oxiranes in the Presence of β‐Cyclodextrin in Water , 2004 .

[5]  N. Asano Glycosidase inhibitors: update and perspectives on practical use. , 2003, Glycobiology.

[6]  L. Somsák,et al.  Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments. , 2003, Current pharmaceutical design.

[7]  Hyunsoo Han A complete asymmetric synthesis of polyhydroxypiperidines , 2003 .

[8]  N. Asano Naturally occurring iminosugars and related compounds: structure, distribution, and biological activity. , 2003, Current topics in medicinal chemistry.

[9]  T. Wrodnigg,et al.  Iminosugars and relatives as antiviral and potential anti-infective agents. , 2003, Current topics in medicinal chemistry.

[10]  P. Compain,et al.  Design, synthesis and biological evaluation of iminosugar-based glycosyltransferase inhibitors. , 2003, Current topics in medicinal chemistry.

[11]  Y. Nishimura gem-Diamine 1-N-iminosugars and related iminosugars, candidate of therapeutic agents for tumor metastasis. , 2003, Current topics in medicinal chemistry.

[12]  G. Bhaskar,et al.  Stereoselective synthesis of L-733,060 , 2003 .

[13]  G. Pandey,et al.  Design and development of a common synthetic strategy for a variety of 1-N-iminosugars. , 2002, Organic letters.

[14]  S. Sabharwal,et al.  1-Aza-sugars from D-glucose. Preparation of 1-deoxy-5-dehydroxymethyl-nojirimycin, its analogues and evaluation of glycosidase inhibitory activity. , 2002, Bioorganic & medicinal chemistry.

[15]  Sung Hye Shin,et al.  Application of optically active 1,2-diol monotosylates for synthesis of β-azido and β-amino alcohols with very high enantiomeric purity. Synthesis of enantiopure (R)-octopamine, (R)-tembamide and (R)-aegeline , 2002 .

[16]  Dong Jun Kim,et al.  Highly efficient synthesis of chiral β-hydroxy sulfides with high enantiomeric purity via CBS-oxazaborolidine-catalyzed borane reduction , 2002 .

[17]  A J Elliott,et al.  Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity. , 2001, Journal of medicinal chemistry.

[18]  K. R. Rao,et al.  Asymmetric synthesis of 2-azido-1-arylethanols from azido aryl ketone-beta-cyclodextrin complexes and sodium borohydride in water. , 2001, Chemical communications.

[19]  E. Molins,et al.  Unprecedented oxidation of a phenylglycinol-derived 2-pyridone: enantioselective synthesis of polyhydroxypiperidines. , 2001, Organic letters.

[20]  J. Treadway,et al.  Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus , 2001, Expert opinion on investigational drugs.

[21]  R. Grubbs,et al.  The development of L2X2Ru=CHR olefin metathesis catalysts: an organometallic success story. , 2001, Accounts of chemical research.

[22]  S. Laschat,et al.  Stereoselective Synthesis of Piperidines , 2001 .

[23]  A. Fürstner,et al.  Ring-Closing Alkyne Metathesis: Application to the Stereoselective Total Synthesis of Prostaglandin E2-1,15-Lactone , 2000 .

[24]  K. Park,et al.  Stereoselective Synthesis of 1,4-Dideoxy-1,4-imino-L-lyxitol and 1,5-Dideoxy-1,5-imino-D-ribitol , 2000 .

[25]  N Zitzmann,et al.  Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[26]  B. Batanero,et al.  Electrosynthesis of N-Substituted Imidazole-2-thiones , 1999 .

[27]  V. Gotor,et al.  Chemoenzymatic synthesis of azacycloalkan-3-ols , 1999 .

[28]  A. Stütz Iminosugars as Glycosidase Inhibitors , 1998 .

[29]  Peter D Smith,et al.  Asymmetric routes to substituted piperidines , 1998 .

[30]  Robert H. Grubbs,et al.  Recent advances in olefin metathesis and its application in organic synthesis , 1998 .

[31]  Y. Igarashi,et al.  1-N-Iminosugars: Potent and Selective Inhibitors of β-Glycosidases , 1998 .

[32]  M. Bols 1-Aza Sugars, Apparent Transition State Analogues of Equatorial Glycoside Formation/Cleavage , 1998 .

[33]  T. Takeuchi,et al.  Synthesis and antimetastatic activity of L-iduronic acid-type 1-N-iminosugars. , 1997, Journal of medicinal chemistry.

[34]  W G Laver,et al.  Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. , 1997, Journal of the American Chemical Society.

[35]  B. Winchester,et al.  Deoxyiminoalditols from aldonolactones--V. Preparation of the four stereoisomers of 1,5-dideoxy-1,5-iminopentitols. Evaluation of these iminopentitols and three 1,5-dideoxy-1,5-iminoheptitols as glycosidase inhibitors. , 1996, Bioorganic & medicinal chemistry.

[36]  Y. Igarashi,et al.  Synthesis of a new inhibitor of α-fucosidase , 1996 .

[37]  G. Jacob,et al.  Glycosylation inhibitors in biology and medicine. , 1995, Current opinion in structural biology.

[38]  J. Dennis,et al.  Inhibitors of carbohydrate processing: A new class of anticancer agents. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

[39]  G. Legler,et al.  Synthesis of 1,5-dideoxy-1,5-imino-d-arabinitol (5-nor-l-fuco-1-deoxynojirimycin) and its application for the affinity purification and characterisation of α-l-fucosidase , 1995 .

[40]  C. Thompson,et al.  Enantioenriched N-(2-chloroalkyl)-3-acetoxypiperidines as potential cholinotoxic agents. Synthesis and preliminary evidence for spirocyclic aziridinium formation , 1995 .

[41]  A. Meyers,et al.  Reinvestigation of a modified Hantzsch thiazole synthesis , 1994 .

[42]  D. M. Ryan,et al.  Rational design of potent sialidase-based inhibitors of influenza virus replication , 1993, Nature.

[43]  S. Pelletier Alkaloids: Chemical and Biological Perspectives , 1992, Alkaloids: Chemical and Biological Perspectives.

[44]  J. Groopman Management of the hematologic complications of human immunodeficiency virus infection. , 1990, Reviews of infectious diseases.

[45]  G. Papandreou,et al.  A new family of five-carbon iminoalditols which are potent glycosidase inhibitors , 1990 .