Hypertonicity-induced inhibition of excitation-contraction coupling in Xenopus twitch fibers.

Mechanical responses such as twitch and tetanus were markedly reduced in Xenopus single twitch fibers which were previously treated with either 125 mM NaCl or 250 mM sucrose hypertonic Ringer despite the retention of nearly normal action potential and caffeine contracture. This inhibition of excitation-contraction coupling was accompanied by a large reduction in membrane capacity to approximately 2 microF/cm2 during and after immersion in the hypertonic Ringer and can possible be attributed to the same origin of disruption of the transverse tubular system as "glycerol effect."

[1]  I. Parker,et al.  Effects of hypertonic solutions on calcium transients in frog twitch muscle fibres. , 1987, The Journal of physiology.

[2]  M. Fujino,et al.  Inhibition of excitation-contraction coupling by a Ca channel blocker nicardipine at low temperature in frog twitch fibers. , 1987, The Japanese journal of physiology.

[3]  H. Ashida General solution of cable theory with both ends sealed. , 1985, Journal of theoretical biology.

[4]  T. Oba,et al.  Mechanical, electrical, and morphological characteristics of skeletal muscle fibers from Xenopus and other species of frogs. , 1983, The Japanese journal of physiology.

[5]  R. H. Adrian,et al.  The voltage dependence of membrane capacity. , 1976, The Journal of physiology.

[6]  S. R. Taylor,et al.  Calcium transients in amphibian muscle. , 1975, Federation proceedings.

[7]  J. Bastian,et al.  Double Sucrose-Gap Method Applied to Single Muscle Fiber of Xenopus laevis , 1974, The Journal of General Physiology.

[8]  P. H. Barry,et al.  Differential effects of glycerol treatment on membrane capacity and excitation—contraction coupling in toad sartorius fibres. With an Appendix , 1973, The Journal of physiology.

[9]  J. Noth,et al.  Tension in Isolated Frog Muscle Fibers Induced by Hypertonic Solutions , 1973, The Journal of general physiology.

[10]  T. Narahashi,et al.  Electrical Properties and Excitation-Contraction Coupling in Skeletal Muscle Treated with Ethylene Glycol , 1972, The Journal of general physiology.

[11]  A. Hodgkin,et al.  Analysis of the membrane capacity in frog muscle , 1972, The Journal of physiology.

[12]  E. G. Henderson Potassium Exchange and Afterpotentials in Frog Sartorius Muscles Treated with Glycerol , 1970, The Journal of general physiology.

[13]  E. B. Ridgway,et al.  On the relationships between membrane potential, calcium transient and tension in single barnacle muscle fibres , 1970, The Journal of physiology.

[14]  R. H. Adrian,et al.  Voltage clamp experiments in striated muscle fibres , 1970, The Journal of physiology.

[15]  A. M. Gordon,et al.  Some Effects of Hypertonic Solutions on Contraction and Excitation-Contraction Coupling in Frog Skeletal Muscles , 1970, The Journal of general physiology.

[16]  J. Howell A lesion of the transverse tubules of skeletal muscle , 1969, The Journal of physiology.

[17]  R. Eisenberg,et al.  Action Potentials, Afterpotentials, and Excitation-Contraction Coupling in Frog Sartorius Fibers without Transverse Tubules , 1969, The Journal of general physiology.

[18]  R. Eisenberg,et al.  Capacitance of the Surface and Transverse Tubular Membrane of Frog Sartorius Muscle Fibers , 1969, The Journal of general physiology.

[19]  C. Caputo Volume and Twitch Tension Changes in Single Muscle Fibers in Hypertonic Solutions , 1968, The Journal of general physiology.

[20]  S. Rapoport,et al.  Some Relations between Changes in the Linear Electrical Properties of Striated Muscle Fibers and Changes in Ultrastructure , 1967, The Journal of general physiology.

[21]  C. Caputo Caffeine- and Potassium-Induced Contractures of Frog Striated Muscle Fibers in Hypertonic Solutions , 1966, The Journal of general physiology.

[22]  D. Wilkie,et al.  The osmotic properties of striated muscle fibres in hypertonic solutions , 1963, The Journal of physiology.

[23]  M. Fujino,et al.  ‘Glycerol Effect’ and the Mechanism Linking Excitation of the Plasma Membrane with Contraction , 1961, Nature.

[24]  J. V. Howarth,et al.  The behaviour of frog muscle in hypertonic solutions , 1958, The Journal of physiology.