Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host
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A. Minami | K. Gomi | H. Oikawa | I. Fujii | H. Ichinose | Mayumi Hatakeyama | Takahiro Ugai | Ryuya Fujii | Takuto Kosaki
[1] R. Cox,et al. Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae , 2015, Chemical science.
[2] J. Frisvad,et al. Reconstitution of biosynthetic machinery for the synthesis of the highly elaborated indole diterpene penitrem. , 2015, Angewandte Chemie.
[3] A. Minami,et al. Rapid Reconstitution of Biosynthetic Machinery for Fungal Metabolites in Aspergillus oryzae: Total Biosynthesis of Aflatrem (I). , 2015 .
[4] A. Minami,et al. Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis. , 2015, Chemical communications.
[5] I. Abe,et al. Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid. , 2014, Journal of the American Chemical Society.
[6] A. Minami,et al. Rapid Reconstitution of Biosynthetic Machinery for Fungal Metabolites in Aspergillus oryzae: Total Biosynthesis of Aflatrem , 2014, Chembiochem : a European journal of chemical biology.
[7] R. Cox,et al. One pathway, many compounds: heterologous expression of a fungal biosynthetic pathway reveals its intrinsic potential for diversity , 2013 .
[8] A. Minami,et al. Biosynthetic assembly of cytochalasin backbone , 2013 .
[9] A. Minami,et al. Identification of ophiobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus. , 2013, Organic letters.
[10] A. Minami,et al. Reconstitution of biosynthetic machinery for indole-diterpene paxilline in Aspergillus oryzae. , 2013, Journal of the American Chemical Society.
[11] Y. Chooi,et al. Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1. , 2011, Metabolic engineering.
[12] A. Minami,et al. Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes in Aspergillus oryzae , 2011, Bioscience, biotechnology, and biochemistry.
[13] R. Cox,et al. Nongenetic reprogramming of a fungal highly reducing polyketide synthase. , 2011, Journal of the American Chemical Society.
[14] R. Cox,et al. The programming role of trans-acting enoyl reductases during the biosynthesis of highly reduced fungal polyketides , 2011 .
[15] H. Wariishi,et al. Construction and Application of a Functional Library of Cytochrome P450 Monooxygenases from the Filamentous Fungus Aspergillus oryzae , 2011, Applied and Environmental Microbiology.
[16] Takayuki Itoh,et al. Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases. , 2010, Nature chemistry.
[17] R. Cox,et al. First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multigene Cluster , 2010, Chembiochem : a European journal of chemical biology.
[18] H. Oikawa,et al. Solanapyrone Synthase, a Possible Diels–Alderase and Iterative Type I Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria solani , 2010, Chembiochem : a European journal of chemical biology.
[19] H. Wariishi,et al. Molecular characterization and isolation of cytochrome P450 genes from the filamentous fungus Aspergillus oryzae , 2010, Archives of Microbiology.
[20] K. Katayama,et al. Purification and N-Terminal Amino Acid Sequence of Solanapyrone Synthase, A Natural Diels-Alderase from Alternaria solani , 2008, Bioscience, biotechnology, and biochemistry.
[21] K. Sakaguchi,et al. A Plant Phytotoxin, Solanapyrone A, Is an Inhibitor of DNA Polymerase β and λ* , 2002, The Journal of Biological Chemistry.
[22] K. Katayama,et al. Total Synthesis of (‐)‐Solanapyrone A (V) via Enzymatic Diels—Alder Reaction of Prosolanapyrone. , 1999 .
[23] K. Katayama,et al. Involvement of Diels–Alder reactions in the biosynthesis of secondary natural products: the late stage of the biosynthesis of the phytotoxins solanapyrones , 1999 .
[24] K. Katayama,et al. Total Synthesis of (−)-Solanapyrone A via Enzymatic Diels−Alder Reaction of Prosolanapyrone , 1998 .
[25] A. Naya,et al. Solanapyrones, Phytotoxins Produced by Alternaria solani: Biosynthesis and Isolation of Minor Components. , 1998, Bioscience, biotechnology, and biochemistry.
[26] K. Katayama,et al. Enzymatic activity and partial purification of solanapyrone synthase: first enzyme catalyzing Diels-Alder reaction. , 1998, Biochimica et biophysica acta.
[27] K. Katayama,et al. Enzymatic activity catalysing exo-selective Diels–Alder reaction in solanapyrone biosynthesis , 1995 .
[28] K. Katayama,et al. First Direct Evidence in Biological Diels-Alder Reaction of Incorporation of Diene-Dienophile Precursors in the Biosynthesis of Solanapyrones , 1994 .
[29] H. Oikawa,et al. Structure and absolute configuration of solanapyrone D: a new clue to the occurrence of biological Diels–Alder reactions , 1989 .
[30] A. Ichihara,et al. Solanapyrones A, B and C, phytotoxic metabolites from the fungus Alternaria solani , 1983 .