Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

[1]  Xiaolu Yang,et al.  TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis , 2008, Cell.

[2]  Alexei Degterev,et al.  Identification of RIP1 kinase as a specific cellular target of necrostatins. , 2008, Nature chemical biology.

[3]  A. Strasser,et al.  Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation–induced thymic lymphoma development , 2008, The Journal of experimental medicine.

[4]  C. Shelton,et al.  Annotating Genes of Known and Unknown Function by Large-Scale Co-Expression Analysis , 2008 .

[5]  J. Kong,et al.  Necrostatin‐1 protects against glutamate‐induced glutathione depletion and caspase‐independent cell death in HT‐22 cells , 2007, Journal of neurochemistry.

[6]  Shao-Cong Sun,et al.  Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. , 2007, Developmental cell.

[7]  S. Miyamoto,et al.  CYLD: a DUB with many talents. , 2007, Developmental cell.

[8]  Masato Tanaka,et al.  Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells , 2007, Bioinform..

[9]  D. Yellon,et al.  Necrostatin: A Potentially Novel Cardioprotective Agent? , 2007, Cardiovascular Drugs and Therapy.

[10]  S. Pfeffer.  Unsolved mysteries in membrane traffic. , 2007, Annual review of biochemistry.

[11]  W. Min,et al.  RIP1-mediated AIP1 Phosphorylation at a 14-3-3-binding Site Is Critical for Tumor Necrosis Factor-induced ASK1-JNK/p38 Activation* , 2007, Journal of Biological Chemistry.

[12]  Jianhong Luo,et al.  Shikonin circumvents cancer drug resistance by induction of a necroptotic death , 2007, Molecular Cancer Therapeutics.

[13]  Y. Hata,et al.  Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways. , 2007, Experimental cell research.

[14]  Léon Personnaz,et al.  Enrichment or depletion of a GO category within a class of genes: which test? , 2007, Bioinform..

[15]  池田 光伸.  Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways , 2007 .

[16]  Jiahuai Han,et al.  Autophagy Contributes to Caspase-independent Macrophage Cell Death* , 2006, Journal of Biological Chemistry.

[17]  M. Lenardo,et al.  Competitive Control of Independent Programs of Tumor Necrosis Factor Receptor-Induced Cell Death by TRADD and RIP1 , 2006, Molecular and Cellular Biology.

[18]  Sudeshna Dutta,et al.  Autophagic programmed cell death by selective catalase degradation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[19]  H. Osada,et al.  Inhibition of ADP/ATP Exchange in Receptor-Interacting Protein-Mediated Necrosis , 2006, Molecular and Cellular Biology.

[20]  K. S. Deshpande,et al.  Human protein reference database—2006 update , 2005, Nucleic Acids Res..

[21]  I. Kurth,et al.  The forkhead transcription factor Foxi1 directly activates the AE4 promoter. , 2006, The Biochemical journal.

[22]  Jian-Dong Li,et al.  The Tumor Suppressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7* , 2005, Journal of Biological Chemistry.

[23]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Alexei Degterev,et al.  Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury , 2005, Nature chemical biology.

[25]  L. Chin,et al.  A Genetic Screen for Candidate Tumor Suppressors Identifies REST , 2005, Cell.

[26]  K. Lindblad-Toh,et al.  Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals , 2005, Nature.

[27]  Hiroaki Kitano,et al.  The PANTHER database of protein families, subfamilies, functions and pathways , 2004, Nucleic Acids Res..

[28]  G. Mills,et al.  The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers , 2004, Nature Medicine.

[29]  K. Fukushima,et al.  Recognition by TNF-α of the GPI-anchor glycan induces apoptosis of U937 cells , 2004 .

[30]  Ajjai Alva,et al.  Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8 , 2004, Science.

[31]  W. Zong,et al.  Alkylating DNA damage stimulates a regulated form of necrotic cell death. , 2004, Genes & development.

[32]  S. Batalov,et al.  A gene atlas of the mouse and human protein-encoding transcriptomes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[33]  K. Fukushima,et al.  Recognition by TNF-alpha of the GPI-anchor glycan induces apoptosis of U937 cells. , 2004, Archives of biochemistry and biophysics.

[34]  Kay Hofmann,et al.  RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. , 2004, Nature immunology.

[35]  P. Clarke,et al.  Developmental cell death: morphological diversity and multiple mechanisms , 2004, Anatomy and Embryology.

[36]  P. Chambon,et al.  Functional interaction between PARP‐1 and PARP‐2 in chromosome stability and embryonic development in mouse , 2003, EMBO Journal.

[37]  P. Vandenabeele,et al.  Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA , 2002, Cell Death and Differentiation.

[38]  Andreas Villunger,et al.  Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis , 2001, Science.

[39]  P. Cullen,et al.  CAPRI regulates Ca2+-dependent inactivation of the Ras-MAPK pathway , 2001, Current Biology.

[40]  C. Ross,et al.  A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease–like 2 , 2001, Nature Genetics.

[41]  Brian Seed,et al.  Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule , 2000, Nature Immunology.

[42]  S. Sohn,et al.  DNA-binding activity of the N-terminal cleavage product of poly(ADP-ribose) polymerase is required for UV mediated apoptosis. , 2000, Journal of cell science.

[43]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[44]  E. Hildt,et al.  Identification of Grb2 As a Novel Binding Partner of  Tumor Necrosis Factor (TNF) Receptor I , 1999, The Journal of experimental medicine.

[45]  S. Nagata,et al.  Caspase-independent Cell Killing by Fas-associated Protein with Death Domain , 1998, The Journal of cell biology.

[46]  W. Fiers,et al.  Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor , 1998, The Journal of experimental medicine.

[47]  W. Fiers,et al.  Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells. , 1997, Cytokine.

[48]  B. Seed,et al.  RIP mediates tumor necrosis factor receptor 1 activation of NF‐kappaB but not Fas/APO‐1‐initiated apoptosis. , 1996, The EMBO journal.

[49]  P. Leder,et al.  RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[50]  W. Fiers,et al.  TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis. , 1995, Journal of inflammation.