Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging.
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J. Voorhees | T. Quan | G. Fisher | George Bou-Gharios | A. Dlugosz | Z. Qin | Y. Xiang | Yingchun Liu | Yan Yang | Zhaoping Qin
[1] F. Mendoza,et al. Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4 , 2018, Laboratory Investigation.
[2] T. Luger,et al. Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis , 2017, Experimental dermatology.
[3] J. Voorhees,et al. Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging , 2015, Aging cell.
[4] S. Feldman,et al. Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012. , 2015, JAMA dermatology.
[5] E. Schadt,et al. Geroscience: Linking Aging to Chronic Disease , 2014, Cell.
[6] P. Courtoy,et al. A Unique C‐terminal Domain Allows Retention of Matrix Metalloproteinase‐27 in the Endoplasmic Reticulum , 2014, Traffic.
[7] J. Voorhees,et al. Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts , 2014, AGE.
[8] Z. Adamski,et al. Basal cell carcinoma – diagnosis , 2013, Contemporary oncology.
[9] J. Voorhees,et al. Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin , 2013, AGE.
[10] T. Quan,et al. Cysteine-rich Protein 61 (CCN1) Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression through αVβ3 Integrin in Human Skin Fibroblasts* , 2013, The Journal of Biological Chemistry.
[11] Li Yang,et al. Inflammation-Mediated Genetic and Epigenetic Alterations Drive Cancer Development in the Neighboring Epithelium upon Stromal Abrogation of TGF-β Signaling , 2013, PLoS genetics.
[12] Lester F. Lau,et al. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets , 2011, Nature Reviews Drug Discovery.
[13] L. Lau. CCN1/CYR61: the very model of a modern matricellular protein , 2011, Cellular and Molecular Life Sciences.
[14] J. Voorhees,et al. CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts , 2011, Journal of Cell Communication and Signaling.
[15] J. Voorhees,et al. Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. , 2010, The Journal of investigative dermatology.
[16] B. de Crombrugghe,et al. Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. , 2010, Arthritis and rheumatism.
[17] J. Voorhees,et al. Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. , 2010, The Journal of investigative dermatology.
[18] Wei Xia,et al. Matrix-degrading metalloproteinases in photoaging. , 2009, The journal of investigative dermatology. Symposium proceedings.
[19] John T Elliott,et al. Cell response to matrix mechanics: focus on collagen. , 2009, Biochimica et biophysica acta.
[20] Shawn M. Sweeney,et al. Candidate Cell and Matrix Interaction Domains on the Collagen Fibril, the Predominant Protein of Vertebrates* , 2008, Journal of Biological Chemistry.
[21] L. Lau,et al. Cytotoxicity of TNFα is regulated by integrin‐mediated matrix signaling , 2007, The EMBO journal.
[22] Lin Lin,et al. Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. , 2006, The American journal of pathology.
[23] Z. Werb,et al. Altered endochondral bone development in matrix metalloproteinase 13-deficient mice , 2004, Development.
[24] J. Voorhees,et al. Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. , 2004, The American journal of pathology.
[25] M. Jacob. Extracellular matrix remodeling and matrix metalloproteinases in the vascular wall during aging and in pathological conditions. , 2003, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[26] Simon C Watkins,et al. CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity , 2002, Molecular and Cellular Biology.
[27] L. Lau,et al. The Angiogenic Factor Cyr61 Activates a Genetic Program for Wound Healing in Human Skin Fibroblasts* , 2001, The Journal of Biological Chemistry.
[28] B. Gilchrest,et al. Skin aging: postulated mechanisms and consequent changes in structure and function. , 2001, Clinics in geriatric medicine.
[29] K. Scharffetter-Kochanek,et al. Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue , 2001, Clinical and experimental dermatology.
[30] H. Yeger,et al. Report on the first international workshop on the CCN family of genes , 2001 .
[31] L. Lau,et al. Adhesion of Human Skin Fibroblasts to Cyr61 Is Mediated through Integrin α6β1 and Cell Surface Heparan Sulfate Proteoglycans* , 2000, The Journal of Biological Chemistry.
[32] C. López-Otín,et al. Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors. , 1999, Cancer research.
[33] E. Ohuchi,et al. Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases. , 1998, European journal of biochemistry.
[34] C. Brinckerhoff,et al. The AP-1 site and MMP gene regulation: what is all the fuss about? , 1997, Matrix biology : journal of the International Society for Matrix Biology.
[35] K. Niederreither,et al. A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic mice , 1996, The Journal of cell biology.
[36] W. Eaglstein. Wound healing and aging. , 1989, Clinics in Geriatric Medicine.
[37] B. Gilchrest,et al. A survey of skin problems and skin care regimens in the elderly. , 1987, Archives of dermatology.
[38] E. Davidson,et al. Alterations in human dermal connective tissue with age and chronic sun damage. , 1962, The Journal of investigative dermatology.
[39] C. López-Otín,et al. Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models. , 2010, Biochimica et biophysica acta.
[40] H. Yeger,et al. Report and abstracts on the first international workshop on the CCN family of genes. , 2001, Molecular pathology : MP.
[41] J. Voorhees,et al. Epithelial and Mesenchymal Cell Biology Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin Address Reprint Requests To , 2022 .