Oestrogen receptor α gene polymorphism is related to aortic valve sclerosis in postmenopausal women

Abstract. Nordström P, Glader CA, Dahlén G, Slunga Birgander L, Lorentzon R, Waldenström A, Lorentzon M (Sports Medicine Unit; Department of Geriatric Medicine; Clinical Chemistry; Section of Cardiology; and National Institute for Working Life, Umeå, Sweden). Oestrogen receptor α gene polymorphism is related to aortic valve sclerosis in postmenopausal women. J Intern Med 2003; 254: 140–146.

[1]  T. Lehtimäki,et al.  Oestrogen receptor gene variation is a determinant of coronary reactivity in healthy young men , 2002, European journal of clinical investigation.

[2]  J. Gustafsson,et al.  Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β , 2002, Science.

[3]  Markus Perola,et al.  Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study , 2002, Journal of Molecular Medicine.

[4]  M. Lauer,et al.  Effect of Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors on the Progression of Calcific Aortic Stenosis , 2001, Circulation.

[5]  R. Choudhury,et al.  New insights into the progression of aortic stenosis: implications for secondary prevention. , 2000, Circulation.

[6]  本間 裕朗 Estrogen Suppresses Transcription of Lipoprotein Lipase Gene : Existence of a unique estrogen response element on the lipoprotein lipase promoter , 2000 .

[7]  M. Schemper,et al.  Predictors of outcome in severe, asymptomatic aortic stenosis. , 2000, The New England journal of medicine.

[8]  T. Lehtimäki,et al.  Association of polymorphism of human α oestrogen receptor gene with coronary artery disease in men: a necropsy study , 2000, BMJ : British Medical Journal.

[9]  R. Pai,et al.  New insights into the progression of aortic stenosis: implications for secondary prevention. , 2000, Circulation.

[10]  E. Vittinghoff,et al.  Postmenopausal Hormone Therapy Increases Risk for Venous Thromboembolic Disease: The Heart and Estrogen/progestin Replacement Study , 2000, Annals of Internal Medicine.

[11]  R. Karas,et al.  The protective effects of estrogen on the cardiovascular system. , 2002, The New England journal of medicine.

[12]  R. Lorentzon,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 1999 by The Endocrine Society Estrogen Receptor Gene Polymorphism, But Not Estradiol Levels, Is Related to Bone Density in Healthy Adolescent Boys: A Cross-Sectional and , 2022 .

[13]  C. Glass,et al.  Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study , 1999, The Lancet.

[14]  P. Hasleton,et al.  Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. , 1998, Transplantation.

[15]  R. Virmani,et al.  Overexpression of transforming growth factor beta1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[16]  An Intronic Sequence Element Mediates Both Activation and Repression of Rat Fibroblast Growth Factor Receptor 2 Pre-mRNA Splicing , 1998, Molecular and Cellular Biology.

[17]  T. Zama,et al.  Genotype distribution of estrogen receptor polymorphisms in men and postmenopausal women from healthy and coronary populations and its relation to serum lipid levels. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[18]  J. Lodder,et al.  Cardiac valve calcification: characteristics of patients with calcification of the mitral annulus or aortic valve , 1997, Heart.

[19]  A. Faedda,et al.  Effects of hormone‐replacement therapy on fibrinolysis in postmenopausal women , 1997 .

[20]  I. Han,et al.  Nonassociation of estrogen receptor genotypes with bone mineral density and estrogen responsiveness to hormone replacement therapy in Korean postmenopausal women. , 1997, The Journal of clinical endocrinology and metabolism.

[21]  R. Cannon,et al.  Effects of hormone-replacement therapy on fibrinolysis in postmenopausal women. , 1997, The New England journal of medicine.

[22]  Catherine M. Otto,et al.  Clinical Factors Associated With Calcific Aortic Valve Disease , 1997 .

[23]  D. Arveiler,et al.  Polymorphisms of the transforming growth factor-beta 1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Témoin de l'Infarctus du Myocarde (ECTIM) Study. , 1996, Hypertension.

[24]  A. Bonev,et al.  Gender differences in coronary artery diameter involve estrogen, nitric oxide, and Ca(2+)-dependent K+ channels. , 1996, Circulation research.

[25]  E. Boerwinkle,et al.  Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma. , 1995, Human molecular genetics.

[26]  W. Border,et al.  Transforming Growth Factor β in Tissue Fibrosis , 1994 .

[27]  C C Laurie,et al.  The effect of an intronic polymorphism on alcohol dehydrogenase expression in Drosophila melanogaster. , 1994, Genetics.

[28]  R. Karas,et al.  Estrogen and the blood vessel wall , 1994, Current opinion in cardiology.

[29]  A. Gown,et al.  Characterization of the Early Lesion of ‘Degenerative’ Valvular Aortic Stenosis: Histological and Immunohistochemical Studies , 1994, Circulation.

[30]  D. Rader,et al.  Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women , 1994, The Lancet.

[31]  R. Derynck,et al.  Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[32]  A. C. Nicholson,et al.  Transforming growth factor-beta up-regulates low density lipoprotein receptor-mediated cholesterol metabolism in vascular smooth muscle cells. , 1992, The Journal of biological chemistry.

[33]  W D Dupont,et al.  Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood. , 1992, Cancer research.

[34]  B. Aronow,et al.  Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene. , 1989, Genes & development.

[35]  R. Renkawitz-Pohl,et al.  Intron and upstream sequences regulate expression of the Drosophila beta 3-tubulin gene in the visceral and somatic musculature, respectively. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[36]  P. Wahl,et al.  Effect of estrogen/progestin potency on lipid/lipoprotein cholesterol. , 1983, The New England journal of medicine.