miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment.

[1]  A. Bouchie.  First microRNA mimic enters clinic , 2013, Nature Biotechnology.

[2]  G. Enikolopov,et al.  Ovarian surface epithelium at the junction area contains cancer-prone stem cell niche , 2013, Nature.

[3]  Eric A Bushong,et al.  Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice , 2012, Science.

[4]  H. Hermeking,et al.  MicroRNAs in the p53 network: micromanagement of tumour suppression , 2012, Nature Reviews Cancer.

[5]  Hans Clevers,et al.  Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas , 2012, Science.

[6]  A. Bader.  miR-34 – a microRNA replacement therapy is headed to the clinic , 2012, Front. Gene..

[7]  Joana A. Vidigal,et al.  Intact p53-Dependent Responses in miR-34–Deficient Mice , 2012, PLoS genetics.

[8]  X. Guo,et al.  miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2 , 2012, The Journal of cell biology.

[9]  Yong Jin Choi,et al.  miR-34 miRNAs provide a barrier for somatic cell reprogramming , 2011, Nature Cell Biology.

[10]  S. Thorgeirsson,et al.  Wild-type p53 controls cell motility and invasion by dual regulation of MET expression , 2011, Proceedings of the National Academy of Sciences.

[11]  W. Gerald,et al.  Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling , 2011, Nature communications.

[12]  B. Verdoodt,et al.  Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas , 2011, Virchows Archiv.

[13]  K. Kelnar,et al.  Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44 , 2010, Nature Medicine.

[14]  L. Trusolino,et al.  MET signalling: principles and functions in development, organ regeneration and cancer , 2010, Nature Reviews Molecular Cell Biology.

[15]  T. Deguchi,et al.  MiR‐34a attenuates paclitaxel‐resistance of hormone‐refractory prostate cancer PC3 cells through direct and indirect mechanisms , 2010, The Prostate.

[16]  F. Gage,et al.  Puma is required for p53-induced depletion of adult stem cells , 2010, Nature Cell Biology.

[17]  H. Hermeking,et al.  Frequent Downregulation of miR-34 Family in Human Ovarian Cancers , 2010, Clinical Cancer Research.

[18]  Y. Pilpel,et al.  p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC , 2010, Cell Death and Differentiation.

[19]  J. Lieberman,et al.  miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53. , 2009, Blood.

[20]  Scott W. Lowe,et al.  Stem cells: The promises and perils of p53 , 2009, Nature.

[21]  K. Leong,et al.  Generation of a prostate from a single adult stem cell , 2008, Nature.

[22]  Yasunori Fujita,et al.  Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. , 2008, Biochemical and biophysical research communications.

[23]  Carola Berking,et al.  Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer , 2008, Cell cycle.

[24]  Wei Wang,et al.  MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. , 2007, Cancer research.

[25]  L. Lim,et al.  A microRNA component of the p53 tumour suppressor network , 2007, Nature.

[26]  David C. Corney,et al.  Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. , 2006, Cancer research.

[27]  P. Dentelli,et al.  p53 Mediates the Accelerated Onset of Senescence of Endothelial Progenitor Cells in Diabetes* , 2006, Journal of Biological Chemistry.

[28]  K. Meletis,et al.  p53 suppresses the self-renewal of adult neural stem cells , 2005, Development.

[29]  Jason A. Koutcher,et al.  Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis , 2005, Nature.

[30]  T. Sun,et al.  Proximal location of mouse prostate epithelial stem cells , 2002, The Journal of cell biology.