Visualization of the spatial and temporal dynamics of MAPK signaling using fluorescence imaging techniques

[1]  Jacob J. Hughey,et al.  High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells , 2014, Cell.

[2]  E. Coffey.  Nuclear and cytosolic JNK signalling in neurons , 2014, Nature Reviews Neuroscience.

[3]  R. Yasuda,et al.  Long-Distance Integration of Nuclear ERK Signaling Triggered by Activation of a Few Dendritic Spines , 2013, Science.

[4]  Kazuhiro Aoki,et al.  Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. , 2013, Molecular cell.

[5]  Y. Hayashi,et al.  Application of FRET probes in the analysis of neuronal plasticity , 2013, Front. Neural Circuits.

[6]  L. Serrano,et al.  Engineering of weak helper interactions for high-efficiency FRET probes , 2013, Nature Methods.

[7]  Jacco van Rheenen,et al.  A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space , 2013, Science Signaling.

[8]  Dhermendra K. Tiwari,et al.  Smart fluorescent proteins: Innovation for barrier‐free superresolution imaging in living cells , 2013, Development, growth & differentiation.

[9]  Masanobu Kano,et al.  Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineurin. , 2013, Cell reports.

[10]  John G. Albeck,et al.  Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals. , 2013, Molecular cell.

[11]  Taichiro Tomida,et al.  The Temporal Pattern of Stimulation Determines the Extent and Duration of MAPK Activation in a Caenorhabditis elegans Sensory Neuron , 2012, Science Signaling.

[12]  Walther Akemann,et al.  Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein. , 2012, Journal of neurophysiology.

[13]  Y. Harada,et al.  Intracellular temperature mapping with a fluorescent polymeric thermometer and fluorescence lifetime imaging microscopy , 2012, Nature Communications.

[14]  M. Miura,et al.  Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure , 2011, The Journal of cell biology.

[15]  Kazuhiro Aoki,et al.  Development of an optimized backbone of FRET biosensors for kinases and GTPases , 2011, Molecular biology of the cell.

[16]  Kami Kim,et al.  Bright and stable near infra-red fluorescent protein for in vivo imaging , 2011, Nature Biotechnology.

[17]  Bryan Q Spring,et al.  Development of a high-dynamic range, GFP-based FRET probe sensitive to oxidative microenvironments , 2011, Experimental biology and medicine.

[18]  Philippe P Roux,et al.  Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases , 2011, Microbiology and Molecular Reviews.

[19]  K. Aoki,et al.  Spatiotemporal regulation of small GTPases as revealed by probes based on the principle of Förster Resonance Energy Transfer (FRET): Implications for signaling and pharmacology. , 2011, Annual review of pharmacology and toxicology.

[20]  Edward L. Huttlin,et al.  A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression , 2010, Cell.

[21]  Chih-yuan Chiang,et al.  A Human MAP Kinase Interactome , 2010, Nature Methods.

[22]  Timothy K Lee,et al.  Single-cell NF-κB dynamics reveal digital activation and analogue information processing , 2010, Nature.

[23]  Moritoshi Sato,et al.  Genetically encoded fluorescent indicators to visualise protein phosphorylation by c-Jun NH2-terminal kinase in living cells , 2010 .

[24]  Yasuyoshi Sakai,et al.  A Novel Fluorescent Sensor Protein for Visualization of Redox States in the Cytoplasm and in Peroxisomes , 2010, Molecular and Cellular Biology.

[25]  E. Choi,et al.  Pathological roles of MAPK signaling pathways in human diseases. , 2010, Biochimica et biophysica acta.

[26]  A. Levchenko,et al.  Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor , 2010, Proceedings of the National Academy of Sciences.

[27]  Jacob J Hughey,et al.  Computational modeling of mammalian signaling networks , 2010, Wiley interdisciplinary reviews. Systems biology and medicine.

[28]  Haluk Resat,et al.  Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor , 2009, Molecular systems biology.

[29]  H. Saito,et al.  Stimulus-Specific Distinctions in Spatial and Temporal Dynamics of Stress-Activated Protein Kinase Kinase Kinases Revealed by a Fluorescence Resonance Energy Transfer Biosensor , 2009, Molecular and Cellular Biology.

[30]  Boris N Kholodenko,et al.  Four‐dimensional dynamics of MAPK information‐processing systems , 2009, Wiley interdisciplinary reviews. Systems biology and medicine.

[31]  Michael Z. Lin,et al.  Mammalian Expression of Infrared Fluorescent Proteins Engineered from a Bacterial Phytochrome , 2009, Science.

[32]  Takeharu Nagai,et al.  An ultramarine fluorescent protein with increased photostability and pH insensitivity , 2009, Nature Methods.

[33]  D. S. Broomhead,et al.  Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription , 2009, Science.

[34]  M. Bastiani,et al.  Axon Regeneration Requires a Conserved MAP Kinase Pathway , 2009, Science.

[35]  Robert E Campbell,et al.  Genetically encoded FRET-based biosensors for multiparameter fluorescence imaging. , 2009, Current opinion in biotechnology.

[36]  K. Svoboda,et al.  A genetically encoded fluorescent sensor of ERK activity , 2008, Proceedings of the National Academy of Sciences.

[37]  J. Tyson,et al.  Design principles of biochemical oscillators , 2008, Nature Reviews Molecular Cell Biology.

[38]  F. Wouters,et al.  pHlameleons: a family of FRET-based protein sensors for quantitative pH imaging. , 2008, Biochemistry.

[39]  Andre Levchenko,et al.  Oscillatory Phosphorylation of Yeast Fus3 MAP Kinase Controls Periodic Gene Expression and Morphogenesis , 2008, Current Biology.

[40]  R. Vaillancourt,et al.  MAP3Ks as central regulators of cell fate during development , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

[41]  C. Bakal,et al.  Phosphorylation Networks Regulating JNK Activity in Diverse Genetic Backgrounds , 2008, Science.

[42]  Yasushi Okamura,et al.  Improving membrane voltage measurements using FRET with new fluorescent proteins , 2008, Nature Methods.

[43]  Karel Svoboda,et al.  The Spread of Ras Activity Triggered by Activation of a Single Dendritic Spine , 2008, Science.

[44]  Walther Akemann,et al.  Engineering of a Genetically Encodable Fluorescent Voltage Sensor Exploiting Fast Ci-VSP Voltage-Sensing Movements , 2008, PloS one.

[45]  Megan N. McClean,et al.  Signal processing by the HOG MAP kinase pathway , 2008, Proceedings of the National Academy of Sciences.

[46]  Ryoichiro Kageyama,et al.  FGF induces oscillations of Hes1 expression and Ras/ERK activation , 2008, Current Biology.

[47]  Robert E Campbell,et al.  Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors , 2008, Nature Methods.

[48]  D. V. Vactor,et al.  Synapses and Growth Cones on Two Sides of a Highwire , 2008, Neuron.

[49]  Jerome T. Mettetal,et al.  The Frequency Dependence of Osmo-Adaptation in Saccharomyces cerevisiae , 2008, Science.

[50]  S. Pfaff,et al.  The Ubiquitin Ligase Phr1 Regulates Axon Outgrowth through Modulation of Microtubule Dynamics , 2007, Neuron.

[51]  A. Winter-Vann,et al.  Integrated activation of MAP3Ks balances cell fate in response to stress , 2007, Journal of cellular biochemistry.

[52]  A. Miyawaki,et al.  Local initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo , 2007, Proceedings of the National Academy of Sciences.

[53]  Joseph Avruch,et al.  MAP kinase pathways: the first twenty years. , 2007, Biochimica et biophysica acta.

[54]  S. Meloche,et al.  Atypical mitogen-activated protein kinases: structure, regulation and functions. , 2007, Biochimica et biophysica acta.

[55]  Maarten Merkx,et al.  Enhanced Sensitivity of FRET‐Based Protease Sensors by Redesign of the GFP Dimerization Interface , 2007, Chembiochem : a European journal of chemical biology.

[56]  J. Marks,et al.  Oxidant Stress during Simulated Ischemia Primes Cardiomyocytes for Cell Death during Reperfusion* , 2007, Journal of Biological Chemistry.

[57]  E. Reddy,et al.  Scaffold proteins of MAP-kinase modules , 2007, Oncogene.

[58]  Wei Chen,et al.  Differential regulation and properties of MAPKs , 2007, Oncogene.

[59]  Y. Umezawa,et al.  Genetically encoded fluorescent indicators to visualize protein phosphorylation by extracellular signal-regulated kinase in single living cells. , 2007, Analytical chemistry.

[60]  Herbert M Sauro,et al.  Oscillatory dynamics arising from competitive inhibition and multisite phosphorylation. , 2007, Journal of theoretical biology.

[61]  Eric Reiter,et al.  GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling , 2006, Trends in Endocrinology & Metabolism.

[62]  Atsushi Miyawaki,et al.  A fluorescent variant of a protein from the stony coral Montipora facilitates dual-color single-laser fluorescence cross-correlation spectroscopy , 2006, Nature Biotechnology.

[63]  S. Davis,et al.  Mitogen‐activated protein kinase/extracellular regulated kinase signalling and memory stabilization: a review , 2006, Genes, brain, and behavior.

[64]  Chao Zhang,et al.  Chemical genetic analysis of the time course of signal transduction by JNK. , 2006, Molecular cell.

[65]  Karel Svoboda,et al.  Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging , 2006, Nature Neuroscience.

[66]  Nathan C Shaner,et al.  A guide to choosing fluorescent proteins , 2005, Nature Methods.

[67]  Tianhai Tian,et al.  Subcellular Localization Determines MAP Kinase Signal Output , 2005, Current Biology.

[68]  H. Saito,et al.  Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases. , 2005, Molecular cell.

[69]  Shinya Kuroda,et al.  Prediction and validation of the distinct dynamics of transient and sustained ERK activation , 2005, Nature Cell Biology.

[70]  Michiyuki Matsuda,et al.  Ras binding opens c‐Raf to expose the docking site for mitogen‐activated protein kinase kinase , 2005, EMBO reports.

[71]  Patrick S Daugherty,et al.  Evolutionary optimization of fluorescent proteins for intracellular FRET , 2005, Nature Biotechnology.

[72]  Yishi Jin,et al.  Regulation of a DLK-1 and p38 MAP Kinase Pathway by the Ubiquitin Ligase RPM-1 Is Required for Presynaptic Development , 2005, Cell.

[73]  Horst Wallrabe,et al.  Imaging protein molecules using FRET and FLIM microscopy. , 2005, Current opinion in biotechnology.

[74]  Mehmet Fatih Yanik,et al.  Neurosurgery: Functional regeneration after laser axotomy , 2004, Nature.

[75]  A. Miyawaki,et al.  Regulated Fast Nucleocytoplasmic Shuttling Observed by Reversible Protein Highlighting , 2004, Science.

[76]  James R. Johnson,et al.  Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression , 2004, Science.

[77]  A. Miyawaki,et al.  Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[78]  Mark A Rizzo,et al.  An improved cyan fluorescent protein variant useful for FRET , 2004, Nature Biotechnology.

[79]  R. Huganir,et al.  MAPK cascade signalling and synaptic plasticity , 2004, Nature Reviews Neuroscience.

[80]  O. Jensen.  Modification-specific proteomics: characterization of post-translational modifications by mass spectrometry. , 2004, Current opinion in chemical biology.

[81]  Uri Alon,et al.  Dynamics of the p53-Mdm2 feedback loop in individual cells , 2004, Nature Genetics.

[82]  M. Dell'Acqua,et al.  Rac–MEKK3–MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock , 2003, Nature Cell Biology.

[83]  Roger Y. Tsien,et al.  A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C , 2003, The Journal of cell biology.

[84]  E. Nishida,et al.  Molecular recognitions in the MAP kinase cascades. , 2003, Cellular signalling.

[85]  A. Miyawaki.  Visualization of the spatial and temporal dynamics of intracellular signaling. , 2003, Developmental cell.

[86]  M. Matsuda,et al.  Activation of Rac and Cdc42 Video Imaged by Fluorescent Resonance Energy Transfer-Based Single-Molecule Probes in the Membrane of Living Cells , 2002, Molecular and Cellular Biology.

[87]  R. Tsien,et al.  Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells , 2002, Science.

[88]  Kenneth M. Murphy,et al.  Kinase Suppressor of Ras (KSR) Is a Scaffold Which Facilitates Mitogen-Activated Protein Kinase Activation In Vivo , 2002, Molecular and Cellular Biology.

[89]  E. Gilles,et al.  Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors , 2002, Nature Biotechnology.

[90]  Y. Umezawa,et al.  Fluorescent indicators for imaging protein phosphorylation in single living cells , 2002, Nature Biotechnology.

[91]  M. Therrien,et al.  KSR is a scaffold required for activation of the ERK/MAPK module. , 2002, Genes & development.

[92]  E. Nishida,et al.  Evidence for Existence of a Nuclear Pore Complex-mediated, Cytosol-independent Pathway of Nuclear Translocation of ERK MAP Kinase in Permeabilized Cells* , 2001, The Journal of Biological Chemistry.

[93]  A. Miyawaki,et al.  Spatio-temporal images of growth-factor-induced activation of Ras and Rap1 , 2001, Nature.

[94]  R. Lefkowitz,et al.  β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3 , 2000 .

[95]  B. Kholodenko,et al.  Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. , 2000, European journal of biochemistry.

[96]  Masatoshi Hagiwara,et al.  A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo , 2000, Nature Biotechnology.

[97]  E. Nishida,et al.  A conserved docking motif in MAP kinases common to substrates, activators and regulators , 2000, Nature Cell Biology.

[98]  A. Kanai,et al.  Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[99]  H. Rubinfeld,et al.  Identification of a Cytoplasmic-Retention Sequence in ERK2* , 1999, The Journal of Biological Chemistry.

[100]  Andrew D. Sharrocks,et al.  Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors , 1999, Molecular and Cellular Biology.

[101]  P. Cohen,et al.  Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro , 1998, Current Biology.

[102]  M. Karin,et al.  JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension. , 1998, Genes & development.

[103]  R. Tsien,et al.  Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin , 1997, Nature.

[104]  E. Nishida,et al.  Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase , 1997, The EMBO journal.

[105]  J. Downward,et al.  Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos. , 1995, Oncogene.

[106]  P. Cohen,et al.  Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. , 1992, The Biochemical journal.

[107]  S. Green,et al.  PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity , 1992, Neuron.

[108]  Philip R. Cohen,et al.  MAP kinase activator from insulin‐stimulated skeletal muscle is a protein threonine/tyrosine kinase. , 1992, The EMBO journal.

[109]  K. Sumiyama,et al.  Live imaging of protein kinase activities in transgenic mice expressing FRET biosensors. , 2012, Cell structure and function.

[110]  J. Lippincott-Schwartz,et al.  Fluorescent proteins for photoactivation experiments. , 2008, Methods in cell biology.

[111]  Eric Reiter,et al.  GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. , 2006, Trends in endocrinology and metabolism: TEM.

[112]  Takuo Suzuki,et al.  Simultaneous real-time detection of initiator- and effector-caspase activation by double fluorescence resonance energy transfer analysis. , 2005, Journal of pharmacological sciences.

[113]  D B Kell,et al.  Oscillations in NF-kappaB signaling control the dynamics of gene expression. , 2004, Science.

[114]  J. Sweatt,et al.  Molecular psychology: roles for the ERK MAP kinase cascade in memory. , 2002, Annual review of pharmacology and toxicology.