Characterization of metabolic health in mouse models of fibrillin-1 perturbation.

[1]  F. Ramirez,et al.  Fibrillin microfibrils in bone physiology. , 2016, Matrix biology : journal of the International Society for Matrix Biology.

[2]  S. Rane,et al.  SMAD3 Negatively Regulates Serum Irisin and Skeletal Muscle FNDC5 and Peroxisome Proliferator-activated Receptor γ Coactivator 1-α (PGC-1α) during Exercise* , 2015, The Journal of Biological Chemistry.

[3]  D. Cai,et al.  Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response , 2014, Nature Medicine.

[4]  S. Klein,et al.  The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β , 2014, Diabetes.

[5]  A. Zwinderman,et al.  Circulating transforming growth factor-β as a prognostic biomarker in Marfan syndrome. , 2013, International journal of cardiology.

[6]  R. Mecham,et al.  Oophorectomy‐induced bone loss is attenuated in MAGP1‐deficient mice , 2012, Journal of cellular biochemistry.

[7]  P. Sun,et al.  Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. , 2011, Cell metabolism.

[8]  W. Wahli,et al.  Smad3 Deficiency in Mice Protects Against Insulin Resistance and Obesity Induced by a High-Fat Diet , 2011, Diabetes.

[9]  C. Baldock,et al.  Assembly of fibrillin microfibrils governs extracellular deposition of latent TGFβ , 2010, Journal of Cell Science.

[10]  D. Keene,et al.  In Vivo Studies of Mutant Fibrillin-1 Microfibrils* , 2010, The Journal of Biological Chemistry.

[11]  Justin S. Weinbaum,et al.  Microfibril-associated Glycoprotein-1, an Extracellular Matrix Regulator of Bone Remodeling* , 2010, The Journal of Biological Chemistry.

[12]  H. Dietz,et al.  Circulating Transforming Growth Factor-&bgr; in Marfan Syndrome , 2009, Circulation.

[13]  C. Meisinger,et al.  Transforming growth factor-beta1 and incident type 2 diabetes: results from the MONICA/KORA case-cohort study, 1984-2002. , 2009, Diabetes care.

[14]  Takako Sasaki,et al.  Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites* , 2009, The Journal of Biological Chemistry.

[15]  Justin S. Weinbaum,et al.  Deficiency in Microfibril-associated Glycoprotein-1 Leads to Complex Phenotypes in Multiple Organ Systems* , 2008, Journal of Biological Chemistry.

[16]  Nicholas H. Putnam,et al.  The Trichoplax genome and the nature of placozoans , 2008, Nature.

[17]  L. Carta,et al.  Fibrillin-Rich Microfibrils—Structural and Instructive Determinants of Mammalian Development and Physiology , 2008, Connective tissue research.

[18]  Marc K. Halushka,et al.  Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome , 2006, Science.

[19]  D. Keene,et al.  Fibrillins 1 and 2 Perform Partially Overlapping Functions during Aortic Development* , 2006, Journal of Biological Chemistry.

[20]  D. Judge,et al.  TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome , 2004 .

[21]  Jessica Geubtner,et al.  Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome. , 2004, The Journal of clinical investigation.

[22]  D. Keene,et al.  Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues. , 2004, Genomics.

[23]  D. Arking,et al.  Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome , 2003, Nature Genetics.

[24]  D. Rifkin,et al.  Latent Transforming Growth Factor β-binding Protein 1 Interacts with Fibrillin and Is a Microfibril-associated Protein* , 2003, The Journal of Biological Chemistry.

[25]  P. Morange,et al.  Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. , 2000, Diabetes.

[26]  M. Gibson,et al.  Microfibril-associated Glycoprotein-1 (MAGP-1) Binds to the Pepsin-resistant Domain of the α3(VI) Chain of Type VI Collagen* , 1997, The Journal of Biological Chemistry.

[27]  J. Spring,et al.  An extracellular matrix protein of jellyfish homologous to mammalian fibrillins forms different fibrils depending on the life stage of the animal. , 1995, Developmental biology.

[28]  W. Hu,et al.  Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils , 1995, The Journal of cell biology.

[29]  R. Mecham,et al.  Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices , 1994, The Journal of cell biology.

[30]  E. Engvall,et al.  Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils , 1986, The Journal of cell biology.

[31]  K. Nath,et al.  Marfan's syndrome. , 1959, Journal of the Indian Medical Association.

[32]  D. Harlan,et al.  Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function* , 2009, Journal of Biological Chemistry.

[33]  D. Judge,et al.  TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. , 2004, The Journal of clinical investigation.

[34]  D. Arking,et al.  Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. , 2003, Nature genetics.