Fears, phobias, and preparedness: toward an evolved module of fear and fear learning.

An evolved module for fear elicitation and fear learning with 4 characteristics is proposed. (a) The fear module is preferentially activated in aversive contexts by stimuli that are fear relevant in an evolutionary perspective. (b) Its activation to such stimuli is automatic. (c) It is relatively impenetrable to cognitive control. (d) It originates in a dedicated neural circuitry, centered on the amygdala. Evidence supporting these propositions is reviewed from conditioning studies, both in humans and in monkeys; illusory correlation studies; studies using unreportable stimuli; and studies from animal neuroscience. The fear module is assumed to mediate an emotional level of fear learning that is relatively independent and dissociable from cognitive learning of stimulus relationships.

[1]  HighWire Press.  Philosophical Transactions of the Royal Society of London , 1781, The London Medical Journal.

[2]  E. Thorndike.  “Animal Intelligence” , 1898, Nature.

[3]  C. LLOVD MORGAN,et al.  Mind in Evolution , 1903, Nature.

[4]  J. Watson,et al.  Conditioned emotional reactions , 1920 .

[5]  F. Mott.  ARCHIVES OF NEUROLOGY AND PSYCHIATRY , 1923 .

[6]  H. Klüver,et al.  PRELIMINARY ANALYSIS OF FUNCTIONS OF THE TEMPORAL LOBES IN MONKEYS , 1939 .

[7]  L. Weiskrantz,et al.  Behavioral changes associated with ablation of the amygdaloid complex in monkeys. , 1956, Journal of comparative and physiological psychology.

[8]  G. Kimble,et al.  Hilgard and Marquis' Conditioning and learning , 1961 .

[9]  E. N. Solokov.  Perception and the conditioned reflex , 1963 .

[10]  W. Bridger,et al.  A COMPARISON OF GSR FEAR RESPONSES PRODUCED BY THREAT AND ELECTRIC SHOCK. , 1964, Journal of psychiatric research.

[11]  J. Emlen,et al.  A comparison of the responses to snakes of lab- and wild-reared rhesus monkeys , 1964 .

[12]  R. Sanderson,et al.  CHARACTERISTICS OF A CONDITIONED RESPONSE IN HUMAN SUBJECTS DURING EXTINCTION TRIALS FOLLOWING A SINGLE TRAUMATIC CONDITIONING TRIAL. , 1964, Journal of abnormal psychology.

[13]  W. F. Prokasy,et al.  Classical conditioning : a symposium , 1965 .

[14]  I. Mandel,et al.  ABOLITION OF THE PRE BY INSTRUCTIONS IN GSR CONDITIONING. , 1965, Journal of experimental psychology.

[15]  R K Clifton,et al.  Heart-rate change as a component of the orienting response. , 1966, Psychological bulletin.

[16]  K. Kurtz,et al.  Conditioned fear and magnitude of startle response: a replication and extension. , 1966, Journal of comparative and physiological psychology.

[17]  R. Rescorla,et al.  Two-process learning theory: Relationships between Pavlovian conditioning and instrumental learning. , 1967, Psychological review.

[18]  E. Fischer.  Conditioned Reflexes , 1942, American journal of physical medicine.

[19]  K. M. Banreti-Fuchs.  Perception without awareness. , 1967, Acta psychologica.

[20]  M. Lader.  Palmar skin conductance measures in anxiety and phobic states. , 1967, Journal of psychosomatic research.

[21]  Interaction between instructions and ISI in conditioning and extinction of the GSR. , 1967, Journal of experimental psychology.

[22]  M. Fuhrer,et al.  Cognitive processes during differential trace and delayed conditioning of the GSR. , 1968, Journal of experimental psychology.

[23]  David A. Sylvester,et al.  The epidemiology of common fears and phobia. , 1969, Comprehensive psychiatry.

[24]  M. Seligman.  On the generality of the laws of learning , 1970 .

[25]  P. Groves,et al.  Habituation: a dual-process theory. , 1970, Psychological review.

[26]  Gregory Razran,et al.  Mind in evolution;: An East-West synthesis of learned behavior and cognition , 1971 .

[27]  P. Rozin,et al.  Specific hungers and poison avoidance as adaptive specializations of learning. , 1971, Psychological review.

[28]  A. Bergin,et al.  Handbook of psychotherapy and behavior change: An empirical analysis , 1971 .

[29]  A. S. Bernstein,et al.  Orienting response and apparent movement toward or away from the observer , 1971 .

[30]  M. Seligman.  Phobias and preparedness , 1971 .

[31]  J. Gray,et al.  The psychology of fear and stress , 1971 .

[32]  P. Ekman.  Universals and cultural differences in facial expressions of emotion. , 1972 .

[33]  Seymour Epstein,et al.  Chapter 8 – THE NATURE OF ANXIETY WITH EMPHASIS UPON ITS RELATIONSHIP TO EXPECTANCY1 , 1972 .

[34]  R. Rescorla,et al.  A theory of Pavlovian conditioning : Variations in the effectiveness of reinforcement and nonreinforcement , 1972 .

[35]  Charles D. Spielberger,et al.  Anxiety: Current Trends in Theory and Research , 1972 .

[36]  W. F. Prokasy,et al.  Classical conditioning II: Current research and theory. , 1972 .

[37]  E. Ramsden.  Biological Boundaries of Learning , 1973 .

[38]  R. Lubow.  Latent inhibition. , 1973, Psychological bulletin.

[39]  M. Dawson.  Can classical conditioning occur without contingency learning? A review and evaluation of the evidence. , 1973, Psychophysiology.

[40]  William F. Prokasy,et al.  CHAPTER 3 – Classical Conditioning , 1973 .

[41]  I. Mandel,et al.  Is there classical conditioning without cognitive expectancy? , 1973, Psychophysiology.

[42]  A. Öhman,et al.  The relationship between spontaneous and stimulus-correlated electrodermal responses in simple and discriminative conditioning paradigms. , 1973, Psychophysiology.

[43]  R. Tremblay,et al.  On aggression. , 1973, The New England journal of medicine.

[44]  J. Falk.  Physiology and Behavior. , 1973 .

[45]  W. F. Prokasy,et al.  Electrodermal Activity in Psychological Research , 1973 .

[46]  N. Mackintosh.  The psychology of animal learning , 1974 .

[47]  Barry Schwartz,et al.  On going back to nature: a review of Seligman and Hager's Biological boundaries of learning , 1974 .

[48]  A. Ohman,et al.  Habituation of the electrodermal orienting reaction to potentially phobic and supposedly neutral stimuli in normal human subjects. , 1974, Biological psychology.

[49]  E. Mayr,et al.  Behavior programs and evolutionary strategies. , 1974, American scientist.

[50]  Daniel G. Brown.  Handbook of Psychotherapy and Behavior Change: An Empirical Analysis , 1975 .

[51]  A. Ohman,et al.  One-trial learning and superior resistance to extinction of autonomic responses conditioned to potentially phobic stimuli. , 1975, Journal of comparative and physiological psychology.

[52]  M. Seligman,et al.  Unprepared phobias: "be prepared". , 1976, Behaviour research and therapy.

[53]  A. Ohman,et al.  The premise of equipotentiality in human classical conditioning: conditioned electrodermal responses to potentially phobic stimuli. , 1976, Journal of experimental psychology. General.

[54]  R. Shiffrin,et al.  Controlled and automatic human information processing: I , 1977 .

[55]  S. Revusky,et al.  Learning as a General Process with an Emphasis on Data from Feeding Experiments , 1977 .

[56]  M. Seligman,et al.  Prepared phobias and obsessions: therapeutic outcome. , 1977, Behaviour research and therapy.

[57]  Effects of instruction on acquisition and extinction of electrodermal responses to fear-relevant stimuli. , 1977, Journal of experimental psychology. Human learning and memory.

[58]  C. Sagan.  The Dragons of Eden: Speculations on the Evolution of Human Intelligence , 1977 .

[59]  Walter Schneider,et al.  Controlled and automatic human information processing: II. Perceptual learning, automatic attending and a general theory. , 1977 .

[60]  A. Ohman,et al.  'Preparedness' and 'arousability' as determinants of electrodermal conditioning. , 1977, Behaviour research and therapy.

[61]  T. Alloway,et al.  Food Aversion Learning , 1977 .

[62]  U Dimberg,et al.  Facial expressions as conditioned stimuli for electrodermal responses: a case of "preparedness"? , 1978, Journal of personality and social psychology.

[63]  A. Ohman,et al.  Orienting and defensive responding in the electrodermal system: palmar-dorsal differences and recovery rate during conditioning to potentially phobic stimuli. , 1978, Psychophysiology.

[64]  A. Ohman,et al.  Modeling processes in the acquisition of fears: vicarious electrodermal conditioning to fear-relevant stimuli. , 1978, Journal of personality and social psychology.

[65]  J. Krebs,et al.  Arms races between and within species , 1979, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[66]  B. Skinner,et al.  Trends in behavior therapy , 1979 .

[67]  S. Mineka.  The role of fear in theories of avoidance learning, flooding, and extinction. , 1979 .

[68]  W. Sluckin.  Fear in animals and man , 1979 .

[69]  A. Logue.  Taste aversion and the generality of the laws of learning. , 1979 .

[70]  A. Ohman,et al.  Cardiovascular and electrodermal responses conditioned to fear-relevant stimuli. , 1979, Psychophysiology.

[71]  D. Delprato.  Hereditary determinants of fears and phobias: A critical review , 1980 .

[72]  J. Requin.  Attention and Performance VII , 1980 .

[73]  J. Eccles.  The emotional brain. , 1980, Bulletin et memoires de l'Academie royale de medecine de Belgique.

[74]  S. Mineka,et al.  Fear of snakes in wild- and laboratory-reared rhesus monkeys (Macaca mulatta) , 1980 .

[75]  M. T. Turvey,et al.  A Sketch of an Ecological Metatheory for Theories of Learning1 , 1980 .

[76]  Arne Öhman,et al.  Skin conductance conditioning to potentially phobic stimuli as a function of interstimulus interval and delay versus trace paradigm. , 1980, Psychophysiology.

[77]  B. Fischhoff,et al.  Journal of Experimental Psychology: Human Learning and Memory , 1980 .

[78]  I. Marks.  Cure and care of neuroses: Theory and practice of behavioral psychotherapy , 1981 .

[79]  H. C. Plotkin,et al.  Indeterminacy is inherent in an inadequate model of evolution, not in nature , 1981, Behavioral and Brain Sciences.

[80]  R. McNally.  Phobias and Preparedness: Instructional Reversal of Electrodermal Conditioning to Fear-Relevant Stimuli , 1981, Psychological reports.

[81]  K. Hugdahl,et al.  Biological vs experiential factors in phobic conditioning. , 1981, Behaviour research and therapy.

[82]  'Preparedness' and the development of aversive associations. , 1981, The British journal of clinical psychology.

[83]  A. Dickinson.  Conditioning and associative learning. , 1981, British medical bulletin.

[84]  R. McNally,et al.  The preparedness theory of phobias and human safety-signal conditioning. , 1982, Behaviour research and therapy.

[85]  F. Masterson,et al.  Species-specific defense reactions and avoidance learning , 1982, The Pavlovian Journal of Biological Science.

[86]  C. G. Costello,et al.  Fears and phobias in women: a community study. , 1982, Journal of abnormal psychology.

[87]  N. McNaughton.  Gray's Neuropsychology of anxiety: An enquiry into the functions of septohippocampal theories , 1982, Behavioral and Brain Sciences.

[88]  Sheila R. Deitz,et al.  Individual differences in electrodermal response conditioning and self-report of discomfort: A phobia analogue , 1982 .

[89]  K. Hollis.  Pavlovian Conditioning of Signal-Centered Action Patterns and Autonomic Behavior: A Biological Analysis of Function , 1982 .

[90]  M. Domjan,et al.  Biological constraints on instrumental and classical conditioning: Retrospect and prospect , 1983 .

[91]  Mark D. Underwood,et al.  Autonomic and somatomotor effects of amygdala central N. stimulation in awake rabbits , 1983, Physiology & Behavior.

[92]  J. Fodor.  The Modularity of mind. An essay on faculty psychology , 1986 .

[93]  M. Domjan.  Biological constraints on instrumental and classical conditioning: implications for general process theory , 1983 .

[94]  D. Siddle,et al.  Orienting and habituation : perspectives in human research , 1983 .

[95]  A. Ohman,et al.  The effects of directional facial cues on electrodermal conditioning to facial stimuli. , 1983, Psychophysiology.

[96]  S. Mineka,et al.  The effects of flooding on reducing snake fear in rhesus monkeys: 6-month follow-up and further flooding. , 1983, Behaviour research and therapy.

[97]  A Sakaguchi,et al.  Subcortical efferent projections of the medial geniculate nucleus mediate emotional responses conditioned to acoustic stimuli , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[98]  A. Öhman,et al.  An Evolutionary Perspective on Human Social Behavior , 1984 .

[99]  S. Mineka,et al.  Observational conditioning of snake fear in rhesus monkeys. , 1984, Journal of abnormal psychology.

[100]  L. Alloy,et al.  Assessment of covariation by humans and animals: the joint influence of prior expectations and current situational information. , 1984, Psychological review.

[101]  J. Brown,et al.  Dental phobia. , 1984, Australian dental journal.

[102]  L. Alloy,et al.  Assessment of covariation by humans and animals: The joint influence of prior expectations and current situational information. , 1984 .

[103]  Michael Davis,et al.  Diazepam blocks fear-enhanced startle elicited electrically from the brainstem , 1984, Physiology & Behavior.

[104]  R. McNally,et al.  The preparedness theory of phobias: the effects of initial fear level on safety-signal conditioning to fear-relevant stimuli. , 1984, Psychophysiology.

[105]  I. Maltzman,et al.  Stimulus significance and bilateral SCRs to potentially phobic pictures. , 1984, Journal of abnormal psychology.

[106]  S. Mineka,et al.  Fear conditioned with escapable and inescapable shock: Effects of a feedback stimulus. , 1984 .

[107]  O. Smith,et al.  Central neural integration for the control of autonomic responses associated with emotion. , 1984, Annual review of neuroscience.

[108]  J. Pearce,et al.  The strength of the orienting response during Pavlovian conditioning. , 1984, Journal of experimental psychology. Animal behavior processes.

[109]  P. Lang,et al.  Individual differences in autonomic response: conditioned association or conditioned fear? , 1985, Psychophysiology.

[110]  Joseph E LeDoux,et al.  Projections to the subcortical forebrain from anatomically defined regions of the medial geniculate body in the rat , 1985, The Journal of comparative neurology.

[111]  E. Katkin,et al.  Blood, sweat, and tears: individual differences in autonomic self-perception. , 1985, Psychophysiology.

[112]  R. Bootzin,et al.  Theoretical Issues in Behavior Therapy , 1985 .

[113]  S. Mineka,et al.  Observational conditioning of snake fear in unrelated rhesus monkeys. , 1985, Journal of abnormal psychology.

[114]  Michael E. Dawson,et al.  Information processing and human autonomic classical conditional. , 1985 .

[115]  E. Foa,et al.  Preparedness and resistance to extinction to fear-relevant stimuli: a failure to replicate. , 1986, Behaviour research and therapy.

[116]  M. Zafiropoulou,et al.  'Preparedness' and the severity and outcome of clinical phobias. , 1986, Behaviour research and therapy.

[117]  A. Ohman,et al.  Orienting and schizophrenia: stimulus significance, attention, and distraction in a signaled reaction time task. , 1986, Journal of abnormal psychology.

[118]  S. Mineka,et al.  Immunization against the observational conditioning of snake fear in rhesus monkeys. , 1986, Journal of abnormal psychology.

[119]  M. Dawson,et al.  Greater resistance to extinction of electrodermal responses conditioned to potentially phobic CSs: a noncognitive process? , 1986, Psychophysiology.

[120]  S. Orr,et al.  Test of the conditioning model of neurosis: differential aversive conditioning of angry and neutral facial expressions in anxiety disorder patients. , 1986, Journal of abnormal psychology.

[121]  P. Lang,et al.  Preparedness and phobia: effects of stimulus content on human visceral conditioning. , 1986, Journal of abnormal psychology.

[122]  A. Ohman,et al.  Face the beast and fear the face: animal and social fears as prototypes for evolutionary analyses of emotion. , 1986, Psychophysiology.

[123]  U. Dimberg,et al.  Facial expressions as excitatory and inhibitory stimuli for conditioned autonomic responses , 1986, Biological Psychology.

[124]  S. Mineka.  A Primate Model of Phobic Fears , 1987 .

[125]  R. McNally,et al.  Preparedness and phobias: a review. , 1987, Psychological bulletin.

[126]  I. Marks.  Fears, phobias, and rituals , 1987 .

[127]  H. Merckelbach.  Electrodermal conditioning to stimuli of evolutionary significance: Failure to replicate the preparedness effect , 1987 .

[128]  S. Mineka,et al.  Second-order conditioning and overshadowing in the observational conditioning of fear in monkeys. , 1987, Behaviour research and therapy.

[129]  U. Dimberg,et al.  Facial reactions, autonomic activity and experienced emotion: A three component model of emotional conditioning , 1987, Biological Psychology.

[130]  Jeffrey A. Gray,et al.  The psychology of fear and stress, 2nd ed. , 1987 .

[131]  I. Marks,et al.  Fears, phobias, and rituals : panic, anxiety, and their disorders , 1987 .

[132]  P. Lang,et al.  The startle probe response: a new measure of emotion? , 1988, Journal of abnormal psychology.

[133]  Joseph E LeDoux,et al.  Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[134]  D. Blanchard,et al.  Ethoexperimental approaches to the biology of emotion. , 1988, Annual review of psychology.

[135]  Michael S. Fanselow,et al.  A functional behavioristic approach to aversively motivated behavior: Predatory imminence as a determinant of the topography of defensive behavior. , 1988 .

[136]  Michael S. Gazzaniga,et al.  Brain modularity: Towards a philosophy of conscious experience. , 1988 .

[137]  Phobias and preparedness: replication and extension. , 1988, Behaviour research and therapy.

[138]  H. Merckelbach,et al.  Many stimuli are frightening, but some are more frightening than others: The contributions of preparedness, dangerousness, and unpredictability to making a stimulus fearful , 1988 .

[139]  P. D. Silva.  Phobias and preparedness: replication and extension. , 1988 .

[140]  J. Aronoff,et al.  The recognition of threatening facial stimuli. , 1988, Journal of personality and social psychology.

[141]  M. Davis,et al.  Enhancement of acoustic startle by electrical stimulation of the amygdala. , 1988, Behavioral neuroscience.

[142]  Robert C. Bolles,et al.  Evolution and learning , 1988 .

[143]  I. Marks.  Fears and phobias , 1989, PSICOLOGIA.

[144]  Chris R. Brewin,et al.  Cognitive psychology and emotional disorders , 1989 .

[145]  P. Lang,et al.  Fear conditioning, meaning, and belongingness: a selective association analysis. , 1989, Journal of abnormal psychology.

[146]  Michael W. Otto,et al.  Anxiety and Its Disorders: The Nature and Treatment of Anxiety and Panic , 1989 .

[147]  K. Hugdahl,et al.  Preparedness and electrodermal fear-conditioning: ontogenetic vs phylogenetic explanations. , 1989, Behaviour research and therapy.

[148]  L. T. Hobhouse,et al.  Mind in Evolution , 1989 .

[149]  D. Lane.  Theoretical foundations of behaviour therapy : Hans J. Eysnck and Irene Martin: Plenum Press, New York $55. ISBN 0-306-42634-X , 1989 .

[150]  A. Öhman,et al.  Preattentive activation of aversive emotions , 1989 .

[151]  S. Mineka,et al.  Observational conditioning of fear to fear-relevant versus fear-irrelevant stimuli in rhesus monkeys. , 1989, Journal of abnormal psychology.

[152]  S. Mineka,et al.  Fear-relevant selective associations and covariation bias. , 1989, Journal of abnormal psychology.

[153]  J. Bargh.  Conditional automaticity: Varieties of automatic influence in social perception and cognition. , 1989 .

[154]  L. Cosmides,et al.  The past explains the present: Emotional adaptations and the structure of ancestral environments , 1990 .

[155]  Joseph E LeDoux.  Information flow from sensation to emotion: Plasticity in the neural computation of stimulus value. , 1990 .

[156]  R. F. Thompson,et al.  Neural mechanisms of classical conditioning in mammals. , 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[157]  S. Yantis,et al.  Mechanisms of attentional priority. , 1990, Journal of experimental psychology. Human perception and performance.

[158]  Joseph E LeDoux,et al.  The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[159]  S. Mineka,et al.  Selective associations in the observational conditioning of fear in rhesus monkeys. , 1990, Journal of experimental psychology. Animal behavior processes.

[160]  O. Smith,et al.  Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region. , 1990, The American journal of physiology.

[161]  M. Gabriel,et al.  Learning and Computational Neuroscience: Foundations of Adaptive Networks , 1990 .

[162]  Joseph E LeDoux,et al.  Topographic organization of neurons in the acoustic thalamus that project to the amygdala , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[163]  S. Mineka,et al.  Selective associations in the origins of phobic fears and their implications for behavior therapy. , 1991 .

[164]  Michael Davis,et al.  Efferent pathway of the amygdala involved in conditioned fear as measured with the fear-potentiated startle paradigm. , 1991, Behavioral neuroscience.

[165]  Paul R. Martin.  Handbook of behavior therapy and psychological science : an integrative approach , 1991 .

[166]  K. Hugdahl,et al.  Hemispheric asymmetry in conditioning to facial emotional expressions. , 1991, Psychophysiology.

[167]  Joseph E. LeDoux,et al.  Emotion and the limbic system concept , 1991 .

[168]  H. Merckelbach,et al.  Phobic dimensions: III. factor analytic approaches to the study of common phobic fears; An updated review of findings obtained with adult subjects , 1991 .

[169]  M. Taussig.  The Nervous System , 1991 .

[170]  R. Desimone.  Face-Selective Cells in the Temporal Cortex of Monkeys , 1991, Journal of Cognitive Neuroscience.

[171]  K. Marinković,et al.  Effects of potentially phobic conditioned stimuli on retention, reconditioning, and extinction of the conditioned skin conductance response. , 1991, Psychophysiology.

[172]  S. Mineka.  Evolutionary Memories, Emotional Processing, and the Emotional Disorders , 1992 .

[173]  R. Kessler,et al.  The genetic epidemiology of phobias in women. The interrelationship of agoraphobia, social phobia, situational phobia, and simple phobia. , 1992, Archives of general psychiatry.

[174]  L. Cosmides,et al.  The Adapted mind : evolutionary psychology and the generation of culture , 1992 .

[175]  Anthony J. Marcel,et al.  Consciousness in Contemporary Science , 1992 .

[176]  Michael Davis,et al.  The role of the amygdala in conditioned fear. , 1992 .

[177]  John P. Aggleton,et al.  The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction. , 1992 .

[178]  G. Davey.  An expectancy model of laboratory preparedness effects , 1992 .

[179]  L. Cosmides,et al.  The psychological foundations of culture. , 1992 .

[180]  A. Maher.  A face in the crowd. , 1992, Orthopedic nursing.

[181]  Joseph E LeDoux.  Brain mechanisms of emotion and emotional learning , 1992, Current Biology.

[182]  A. Arntz,et al.  Covariation detection in treated and untreated spider phobics. , 1992, Journal of abnormal psychology.

[183]  Paul J. Whalen,et al.  Amygdaloid contributions to conditioned arousal and sensory information processing. , 1992 .

[184]  P. Gloor,et al.  Role of the amygdala in temporal lobe epilepsy. , 1992 .

[185]  K. Hugdahl,et al.  Right hemisphere representation of autonomic conditioning to facial emotional expressions. , 1993, Psychophysiology.

[186]  D. Cicchetti.  Emotion and Adaptation , 1993 .

[187]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[188]  Resistance to extinction of fear-relevant stimuli: preparedness or selective sensitization? , 1993, Journal of experimental psychology. General.

[189]  S. Levine,et al.  Early experience effects on the development of fear in the squirrel monkey. , 1993, Behavioral and neural biology.

[190]  Arne Öhman,et al.  Fear and anxiety as emotional phenomena: Clinical phenomenology, evolutionary perspectives, and information-processing mechanisms. , 1993 .

[191]  A. Ohman,et al.  Backward masking and skin conductance responses after conditioning to nonfeared but fear-relevant stimuli in fearful subjects. , 1993, Psychophysiology.

[192]  A. Ohman,et al.  Preattentive processing, preparedness and phobias: effects of instruction on conditioned electrodermal responses to masked and non-masked fear-relevant stimuli. , 1993, Behaviour research and therapy.

[193]  Effects of experience with live insects on the development of fear of snakes in squirrel monkeys, Saimiri sciureus , 1993, Animal Behaviour.

[194]  D. Klein.  False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis. , 1993, Archives of general psychiatry.

[195]  Joseph E. LeDoux,et al.  Emotional memory systems in the brain , 1993, Behavioural Brain Research.

[196]  S. Mineka,et al.  Mechanisms involved in the observational conditioning of fear. , 1993, Journal of experimental psychology. General.

[197]  A. Ohman,et al.  On the automatic nature of phobic fear: conditioned electrodermal responses to masked fear-relevant stimuli. , 1993, Journal of abnormal psychology.

[198]  N. Birbaumer,et al.  The Structure of emotion : psychophysiological, cognitive, and clinical aspects , 1993 .

[199]  N Birbaumer,et al.  Classical conditioning after cerebellar lesions in humans. , 1993, Behavioral neuroscience.

[200]  A. Ohman,et al.  Masking the face: recognition of emotional facial expressions as a function of the parameters of backward masking. , 1993, Scandinavian journal of psychology.

[201]  L. F. Barrett,et al.  Handbook of Emotions , 1993 .

[202]  P. Lovibond.  Conditioning and Cognitive-Behaviour Therapy , 1993, Behaviour Change.

[203]  W. J. Williams,et al.  Conscious and nonconscious processes: an ERP index of an anticipatory response in a conditioning paradigm using visually masked stimuli. , 1994, Psychophysiology.

[204]  E. Katkin,et al.  The relationship between cardiovascular reactivity and heartbeat detection. , 1994, Psychophysiology.

[205]  U Dimberg,et al.  Nonconscious associative learning: Pavlovian conditioning of skin conductance responses to masked fear-relevant facial stimuli. , 1994, Psychophysiology.

[206]  S. Rachman,et al.  Stimulus estimation and the overprediction of fear. , 1994, The British journal of clinical psychology.

[207]  A. Ohman,et al.  "Unconscious anxiety": phobic responses to masked stimuli. , 1994, Journal of abnormal psychology.

[208]  P. Lovibond,et al.  Electrodermal and subjective reactions to fear‐relevant stimuli under threat of shock , 1994 .

[209]  C. MacLeod,et al.  Cognitive approaches to emotion and emotional disorders. , 1994, Annual review of psychology.

[210]  M. Telch,et al.  Proximity to safety and its effects on fear prediction bias. , 1994, Behaviour research and therapy.

[211]  H. J. Eysenck,et al.  Advances in psychophysiology: J.R. Jennings, P.K. Ackles & M.G.H. Coles (Eds) Vol.5 (1993).320 pp. £42.50 (hardback). ISBN 185302 191 1 , 1994 .

[212]  M. Fanselow.  Neural organization of the defensive behavior system responsible for fear , 1994, Psychonomic bulletin & review.

[213]  Dc Washington.  Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[214]  A. Öhman,et al.  Automatically elicited fear: Conditioned skin conductance responses to masked facial expressions , 1994 .

[215]  S. Mineka,et al.  Fear-relevant illusory correlations: what types of associations promote judgmental bias? , 1995, Journal of abnormal psychology.

[216]  J. Clarke,et al.  Danger expectancies and insight in acrophobia. , 1995, Behaviour research and therapy.

[217]  Joseph E. LeDoux,et al.  LTP is accompanied by commensurate enhancement of auditory-evoked responses in a fear conditioning circuit , 1995, Neuron.

[218]  R. Howard,et al.  Fear conditioning, preparedness, and the contingent negative variation. , 1995, Psychophysiology.

[219]  S. Mineka,et al.  Expectancy bias as sole or partial account of selective associations? , 1995, Behavioral and Brain Sciences.

[220]  G. Davey,et al.  The Effect of Prior Fear Levels on UCS-expectancy Ratings to a Fear-relevant Stimulus , 1995, The Quarterly journal of experimental psychology. A, Human experimental psychology.

[221]  A. Öhman.  Eggs in more than one basket: Mediating mechanisms between evolution and phobias , 1995, Behavioral and Brain Sciences.

[222]  Scott T. Grafton,et al.  Functional anatomy of human eyeblink conditioning determined with regional cerebral glucose metabolism and positron-emission tomography. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[223]  Michael S. Gazzaniga,et al.  Consciousness and the cerebral hemispheres. , 1995 .

[224]  G. Davey,et al.  Preparedness and phobias: Specific evolved associations or a generalized expectancy bias? , 1995, Behavioral and Brain Sciences.

[225]  J. D. Nichols,et al.  Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. , 1997, Science.

[226]  N. Alpert,et al.  A positron emission tomographic study of simple phobic symptom provocation. , 1995, Archives of general psychiatry.

[227]  Joseph E LeDoux,et al.  Impaired fear conditioning following unilateral temporal lobectomy in humans , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[228]  J. Clarke,et al.  THE ETIOLOGY OF PHOBIAS: A NONASSOCIATIVE ACCOUNT , 1995 .

[229]  D. Klein.  Counterevidence from psychopharmacology, psychopathology, and psychobiology , 1995, Behavioral and Brain Sciences.

[230]  A. Tomarken.  What is the critical evidence favoring expectancy bias theory, and where is it? , 1995, Behavioral and Brain Sciences.

[231]  A. Arntz,et al.  Covariation bias in phobic women: the relationship between a priori expectancy, on-line expectancy, autonomic responding, and a posteriori contingency judgment. , 1995, Journal of abnormal psychology.

[232]  P. Salkovskis,et al.  Phobic beliefs: do cognitive factors play a role in specific phobias? , 1995, Behaviour research and therapy.

[233]  R. D. Kavanaugh,et al.  Emotion : interdisciplinary perspectives , 1996 .

[234]  T. Johnston.  Selective costs and benefits of in the evolution of learning , 1996 .

[235]  Arne Öhman,et al.  Behold the wrath: Psychophysiological responses to facial stimuli , 1996 .

[236]  P. Lovibond,et al.  Conditioning with facial expressions of emotion: effects of CS sex and age. , 1996, Psychophysiology.

[237]  E. Bizzi,et al.  The Cognitive Neurosciences , 1996 .

[238]  R. Rapee.  Current controversies in the anxiety disorders , 1996 .

[239]  J. Elman,et al.  Rethinking Innateness: A Connectionist Perspective on Development , 1996 .

[240]  A. Hamm,et al.  Affective learning: awareness and aversion. , 1996, Psychophysiology.

[241]  T. Brown,et al.  Psychometric properties of the Depression Anxiety Stress Scales (DASS) in clinical samples. , 1997, Behaviour research and therapy.

[242]  S. Mineka,et al.  Covariation bias for blood-injury stimuli and aversive outcomes. , 1997, Behaviour research and therapy.

[243]  Geraint Rees,et al.  Consciousness lost and found , 1997 .

[244]  Edwin W. Cook,et al.  Differentiating orienting, startle, and defense responses: The role of affect and its implications for psychopathology. , 1997 .

[245]  Jonathan D. Cohen,et al.  Computational modeling of emotion: explorations through the anatomy and physiology of fear conditioning , 1997, Trends in Cognitive Sciences.

[246]  M. Bradley,et al.  Motivated attention: Affect, activation, and action. , 1997 .

[247]  A. Öhman,et al.  Pavlovian Conditioning to Social Stimuli: Backward Masking and the Dissociation of Implicit and Expl , 1997 .

[248]  Dissociations between Covariation Bias and Expectancy Bias for Fear-relevant Stimuli , 1997 .

[249]  Sensitizing experiences and fear acquisition: comment on Masataka (1993) , 1997, Animal Behaviour.

[250]  Joseph E LeDoux,et al.  Fear Conditioning Enhances Different Temporal Components of Tone-Evoked Spike Trains in Auditory Cortex and Lateral Amygdala , 1997, Neuron.

[251]  R. Rapee,et al.  Covariation bias for phylogenetic versus ontogenetic fear-relevant stimuli. , 1997, Behaviour research and therapy.

[252]  Peter J. Lang,et al.  Attention and Orienting : Sensory and Motivational Processes , 1997 .

[253]  Michael Davis.  The neurophysiological basis of acoustic startle modulation: Research on fear motivation and sensory gating. , 1997 .

[254]  B. Cuthbert,et al.  Fear and the startle reflex: blink modulation and autonomic response patterns in animal and mutilation fearful subjects. , 1997, Psychophysiology.

[255]  H Fischer,et al.  The amygdala and individual differences in human fear conditioning , 1997, Neuroreport.

[256]  Joseph E LeDoux,et al.  Fear conditioning induces associative long-term potentiation in the amygdala , 1997, Nature.

[257]  A. Ohman,et al.  Emotional conditioning to masked stimuli: expectancies for aversive outcomes following nonrecognized fear-relevant stimuli. , 1998, Journal of experimental psychology. General.

[258]  M. Kindt,et al.  Illusory correlation and social anxiety. , 1998, Behaviour research and therapy.

[259]  J. Andersson,et al.  Functional neuroanatomical correlates of electrodermal activity: a positron emission tomographic study. , 1998, Psychophysiology.

[260]  Michelle G. Craske,et al.  Anxiety Disorders: Psychological Approaches To Theory And Treatment , 1998 .

[261]  A. Arnsten.  Catecholamine modulation of prefrontal cortical cognitive function , 1998, Trends in Cognitive Sciences.

[262]  Karl J. Friston,et al.  Brain Systems Mediating Aversive Conditioning: an Event-Related fMRI Study , 1998, Neuron.

[263]  Joseph E LeDoux,et al.  Human Amygdala Activation during Conditioned Fear Acquisition and Extinction: a Mixed-Trial fMRI Study , 1998, Neuron.

[264]  R. Dolan,et al.  Conscious and unconscious emotional learning in the human amygdala , 1998, Nature.

[265]  Michael D. Robinson.  Running from William James' bear: A review of preattentive mechanisms and their contributions to emotional experience. , 1998 .

[266]  Michael Davis Young,et al.  Fear and Anxiety: Possible Roles of the Amygdala and Bed Nucleus of the Stria Terminalis , 1998 .

[267]  J. Schulkin,et al.  From normal fear to pathological anxiety. , 1998, Psychological review.

[268]  James L. McGaugh,et al.  Mechanisms of emotional arousal and lasting declarative memory , 1998, Trends in Neurosciences.

[269]  Joseph E. LeDoux,et al.  How danger is encoded: towards a systems, cellular, and computational understanding of cognitive-emotional interactions , 1999 .

[270]  M. Fendt,et al.  The neuroanatomical and neurochemical basis of conditioned fear , 1999, Neuroscience & Biobehavioral Reviews.

[271]  R. Dolan,et al.  A subcortical pathway to the right amygdala mediating "unseen" fear. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[272]  A. Ohman,et al.  Fear appears fast: temporal course of startle reflex potentiation in animal fearful subjects. , 1999, Psychophysiology.

[273]  Joseph E LeDoux,et al.  Why We Think Plasticity Underlying Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala , 1999, Neuron.

[274]  Francisco Esteves,et al.  The Face of Wrath: Critical Features for Conveying Facial Threat , 1999 .

[275]  R. Nicoll,et al.  Long-term potentiation--a decade of progress? , 1999, Science.

[276]  T. Dalgleish,et al.  Handbook of cognition and emotion , 1999 .

[277]  L. Heimer,et al.  The Concepts of the Ventral Striatopallidal System and Extended Amygdala , 1999, Annals of the New York Academy of Sciences.

[278]  J. McGinty.  Advancing from the ventral striatum to the extended amygdala. Implications for neuropsychiatry and drug abuse. Introduction. , 1999, Annals of the New York Academy of Sciences.

[279]  D. Lundqvist,et al.  Unconscious emotion : Evolutionary perspectives, psychophysiological data, and neuropsychological mechanisms , 2000 .

[280]  M. Gazzaniga,et al.  The new cognitive neurosciences , 2000 .

[281]  P. Lang,et al.  Fear and anxiety: animal models and human cognitive psychophysiology. , 2000, Journal of affective disorders.

[282]  U. Dimberg,et al.  Unconscious Facial Reactions to Emotional Facial Expressions , 2000, Psychological science.

[283]  R. Davidson,et al.  Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence. , 2000, Science.

[284]  G. Davey,et al.  Phobias: A Handbook of Theory, Research and Treatment , 2000, Journal of Cognitive Psychotherapy.

[285]  Kenneth Hugdahl,et al.  Cognition and the autonomic nervous system: Orienting, anticipation, and conditioning. , 2000 .

[286]  M. Gazzaniga.  The new cognitive neurosciences, 2nd ed. , 2000 .

[287]  A. Ohman,et al.  The face in the crowd revisited: a threat advantage with schematic stimuli. , 2001, Journal of personality and social psychology.

[288]  A. Öhman,et al.  Nonconscious Fear Conditioning, Visceral Perception, and the Development of Gut Feelings , 2001, Psychological science.

[289]  S. Mineka,et al.  A modern learning theory perspective on the etiology of panic disorder. , 2001, Psychological review.

[290]  T. Brown,et al.  Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. , 2001, Journal of abnormal psychology.

[291]  A. Ohman,et al.  Emotion drives attention: detecting the snake in the grass. , 2001, Journal of experimental psychology. General.

[292]  R. Peters,et al.  Digital video playback and visual communication in lizards , 2002, Animal Behaviour.

[293]  Elizabeth A. Phelps,et al.  The cognitive neuroscience of emotion , 2002 .

[294]  A. Öhman,et al.  On the automaticity of autonomic responses in emotion: An evolutionary perspective. , 2003 .