Holothurian glycosaminoglycan inhibits metastasis via inhibition of P-selectin in B16F10 melanoma cells

[1]  L. Borsig,et al.  The role of VLA-4 binding for experimental melanoma metastasis and its inhibition by heparin. , 2014, Thrombosis research.

[2]  Li-jing Wang,et al.  P-Selectin-Mediated Platelet Adhesion Promotes the Metastasis of Murine Melanoma Cells , 2014, PloS one.

[3]  Daohai Zhang,et al.  Holothurian Glycosaminoglycan Inhibits Metastasis and Thrombosis via Targeting of Nuclear Factor-κB/Tissue Factor/Factor Xa Pathway in Melanoma B16F10 Cells , 2013, PloS one.

[4]  W. Sellers,et al.  Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance , 2013, Nature.

[5]  Liljana Mervic Time Course and Pattern of Metastasis of Cutaneous Melanoma Differ between Men and Women , 2012, PloS one.

[6]  Jingyun Li,et al.  Retinoic Acid Signaling Plays a Restrictive Role in Zebrafish Primitive Myelopoiesis , 2012, PloS one.

[7]  L. Borsig,et al.  Cancer Cell Adhesion and Metastasis: Selectins, Integrins, and the Inhibitory Potential of Heparins , 2012, International journal of cell biology.

[8]  Sejeong Shin,et al.  Integrin Trafficking and Tumor Progression , 2011, International journal of cell biology.

[9]  L. Borsig,et al.  Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P‐selectin , 2011, Journal of thrombosis and haemostasis : JTH.

[10]  K. Konstantopoulos,et al.  Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer , 2011, Journal of Cell Science.

[11]  C. Holmes,et al.  The platelet contribution to cancer progression , 2011, Journal of thrombosis and haemostasis : JTH.

[12]  Laurie J. Gay,et al.  Contribution of platelets to tumour metastasis , 2011, Nature Reviews Cancer.

[13]  L. Zheng,et al.  Study on anti-metastasis of heparin derivatives as ligand antagonist of p-selectin. , 2010, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[14]  V. Golubovskaya Focal adhesion kinase as a cancer therapy target. , 2010, Anti-cancer agents in medicinal chemistry.

[15]  J. Steffensen,et al.  Hypoxia-induced metastasis model in embryonic zebrafish , 2010, Nature Protocols.

[16]  M. Schön,et al.  Deadly allies: the fatal interplay between platelets and metastasizing cancer cells. , 2010, Blood.

[17]  L. Borsig,et al.  Selectins as Mediators of Lung Metastasis , 2010, Cancer Microenvironment.

[18]  Yin Lu,et al.  Acidic mucopolysaccharide from holothuria leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro , 2009, Cancer biology & therapy.

[19]  R. Weinberg,et al.  Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs , 2009, Proceedings of the National Academy of Sciences.

[20]  Yan-guang Gao,et al.  Inhibitory effects of chemically modified heparin on the P-selectin-mediated adhesion of breast cancer cells in vitro. , 2009, Molecular medicine reports.

[21]  E. M. Reyes-Reyes,et al.  Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells. , 2008, Experimental cell research.

[22]  T. Tsuruo,et al.  Platelet aggregation in the formation of tumor metastasis. , 2008, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

[23]  L. Borsig,et al.  P‐selectin‐ and heparanase‐dependent antimetastatic activity of non‐anticoagulant heparins , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[24]  M. Schön,et al.  P-selectin , 2007, Expert opinion on therapeutic targets.

[25]  L. Borsig Antimetastatic activities of modified heparins: selectin inhibition by heparin attenuates metastasis. , 2007, Seminars in thrombosis and hemostasis.

[26]  J. Esko,et al.  Selectin Blocking Activity of a Fucosylated Chondroitin Sulfate Glycosaminoglycan from Sea Cucumber , 2007, Journal of Biological Chemistry.

[27]  R. Albrecht,et al.  Cloning and functional characterization of recombinant equine P-selectin. , 2007, Veterinary immunology and immunopathology.

[28]  N. Callewaert,et al.  P-selectin mediates metastatic progression through binding to sulfatides on tumor cells. , 2007, Glycobiology.

[29]  John D. Roberts,et al.  P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin. , 2006, Experimental cell research.

[30]  D. Schlaepfer,et al.  Integrin-regulated FAK-Src signaling in normal and cancer cells. , 2006, Current opinion in cell biology.

[31]  S. Hao,et al.  Chemically modified heparin inhibits the in vitro adhesion of nonsmall cell lung cancer cells to P-selectin , 2006, Journal of Cancer Research and Clinical Oncology.

[32]  J. Geng,et al.  P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis , 2006, Archivum Immunologiae et Therapiae Experimentalis.

[33]  A. Varki,et al.  L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest. , 2006, Cancer research.

[34]  F. Guadagni,et al.  Prognostic value of soluble P‐selectin levels in colorectal cancer , 2004, International journal of cancer.

[35]  Yifa Zhou,et al.  Modified Heparin Inhibits P-selectin-mediated Cell Adhesion of Human Colon Carcinoma Cells to Immobilized Platelets under Dynamic Flow Conditions* , 2004, Journal of Biological Chemistry.

[36]  Zachary Shriver,et al.  Roles of heparan-sulphate glycosaminoglycans in cancer , 2002, Nature Reviews Cancer.

[37]  Ajit Varki,et al.  Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[38]  A. Varki,et al.  Heparin Inhibition of Selectin-Mediated Interactions during the Hematogenous Phase of Carcinoma Metastasis: Rationale for Clinical Studies in Humans , 2002, Seminars in thrombosis and hemostasis.

[39]  M. Hollingsworth,et al.  Overexpression of MUC1 reconfigures the binding properties of tumor cells , 2001, International journal of cancer.

[40]  A. Varki,et al.  P-selectin, carcinoma metastasis and heparin: novel mechanistic connections with therapeutic implications. , 2001, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[41]  David R. Nadeau,et al.  Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[42]  T. Mayadas,et al.  Dimerization of P-selectin in platelets and endothelial cells. , 2000, Blood.

[43]  J. Geng,et al.  Heparan Sulfate-Like Proteoglycans Mediate Adhesion of Human Malignant Melanoma A375 Cells to P-Selectin Under Flow1 , 2000, The Journal of Immunology.

[44]  A. Varki,et al.  P-selectin deficiency attenuates tumor growth and metastasis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Chi‐Huey Wong,et al.  Small Molecules as Structural and Functional Mimics of Sialyl Lewis X Tetrasaccharide in Selectin Inhibition: A Remarkable Enhancement of Inhibition by Additional Negative Charge and/or Hydrophobic Group , 1997 .

[46]  Zaverio M. Ruggeri,et al.  Role of 3 Integrins in Melanoma Cell Adhesion to Activated Platelets under Flow (*) , 1996, The Journal of Biological Chemistry.

[47]  J. P. Stone,et al.  P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer. , 1993, The Journal of clinical investigation.

[48]  D. Wagner,et al.  P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells , 1992, The Journal of cell biology.

[49]  A. Varki,et al.  Heparin attenuates metastasis mainly due to inhibition of P- and L-selectin, but non-anticoagulant heparins can have additional effects. , 2007, Thrombosis research.

[50]  Chi Chen,et al.  Inhibition of human CD24 binding to platelet-bound P-selectin by monoclonal antibody. , 2004, Proceedings of the Western Pharmacology Society.