Gradients of Atrial Refractoriness and Inducibility of Atrial Fibrillation due to Stimulation of Ganglionated Plexi

Introduction. The mechanism(s) whereby atrial ectopy induces atrial fibrillation (AF) is still poorly understood.

[1]  Haran Burri,et al.  Quantitative study of nerves of the human left atrium. , 2005, Heart rhythm.

[2]  D. Hopkins,et al.  Gross and microscopic anatomy of the canine intrinsic cardiac nervous system , 1994, The Anatomical record.

[3]  D. Pauza,et al.  Morphology of the Intrinsic Cardiac Nervous System in the Dog: A Whole-Mount Study Employing Histochemical Staining with Acetylcholinesterase , 2003, Cells Tissues Organs.

[4]  W. Rheinboldt,et al.  A COMPUTER MODEL OF ATRIAL FIBRILLATION. , 1964, American heart journal.

[5]  H. Nakagawa,et al.  Electrical Stimulation to Identify Neural Elements on the Heart: Their Role in Atrial Fibrillation , 2005, Journal of Interventional Cardiac Electrophysiology.

[6]  Marco Bettoni,et al.  Autonomic Tone Variations Before the Onset of Paroxysmal Atrial Fibrillation , 2002, Circulation.

[7]  José Jalife,et al.  Rotors and Spiral Waves in Atrial Fibrillation , 2003, Journal of cardiovascular electrophysiology.

[8]  C. Tai,et al.  Electrophysiologic characteristics in initiation of paroxysmal atrial fibrillation from a focal area. , 2001, Journal of the American College of Cardiology.

[9]  Sander Verheule,et al.  Arrhythmogenic Substrate of the Pulmonary Veins Assessed by High-Resolution Optical Mapping , 2003, Circulation.

[10]  R. Lazzara,et al.  Selective In Situ Parasympathetic Control of the Canine Sinoatrial and Atrioventricular Nodes , 1973, Circulation research.

[11]  J Clémenty,et al.  Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. , 1998, The New England journal of medicine.

[12]  S. A. Chen,et al.  Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation. , 2000, Cardiovascular research.

[13]  D. Hopkins,et al.  Gross and microscopic anatomy of the human intrinsic cardiac nervous system , 1997, The Anatomical record.

[14]  R. Lazzara,et al.  Experimental model for paroxysmal atrial fibrillation arising at the pulmonary vein-atrial junctions. , 2006, Heart rhythm.

[15]  D SCHERF,et al.  Studies on Auricular Tachycardia Caused by Aconitine Administration , 1947, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[16]  L. Biblo,et al.  Characterization of Sinoatrial Parasympathetic Innervation in Humans , 1999, Journal of cardiovascular electrophysiology.

[17]  P B Corr,et al.  The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure. , 1991, The Journal of thoracic and cardiovascular surgery.

[18]  L. Biblo,et al.  Identification and Characterization of Atrioventricular Parasympathetic Innervation in Humans , 2002, Journal of cardiovascular electrophysiology.

[19]  P. Martin,et al.  Prolongation of cardiac cycle length attenuates negative dromotropic response to selective vagal stimuli. , 1989, Journal of the autonomic nervous system.

[20]  J Clémenty,et al.  A focal source of atrial fibrillation treated by discrete radiofrequency ablation. , 1997, Circulation.

[21]  O. Alfieri,et al.  Pulmonary Vein Denervation Enhances Long-Term Benefit After Circumferential Ablation for Paroxysmal Atrial Fibrillation , 2004, Circulation.

[22]  W. C. Randall,et al.  Vagal postganglionic innervation of the canine sinoatrial node. , 1987, Journal of the autonomic nervous system.

[23]  M. Allessie,et al.  Experimental evaluation of Moe's multiple wavelet hypothesis of atrial fibrillation , 1985 .

[24]  R. Lazzara,et al.  Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation. , 2005, Heart rhythm.

[25]  G. Moe,et al.  On the multiple wavelet hypothesis o f atrial fibrillation. , 1962 .

[26]  Ralph Lazzara,et al.  Autonomically induced conversion of pulmonary vein focal firing into atrial fibrillation. , 2005, Journal of the American College of Cardiology.

[27]  Mélèze Hocini,et al.  Basic and clinical electrophysiology of pulmonary vein ectopy. , 2002, Cardiovascular research.