Clinical prevalence and associated intraoperative surgical complications of reproductive tract lesions in pot-bellied pigs undergoing ovariohysterectomy: 298 cases (2006–2016)

To address the current dearth of clinically relevant publications regarding ovariohysterectomy (OVH) in the domestic pot-bellied pig (PBP), the present study aims to report prevalence of uterine lesions, intraoperative complications, and short and long-term survival in this species (n=298). Prevalence of lesions included uterine neoplasia 11.4 per cent (34/298), pyometra 1.6 per cent (5/298) and cystic endometrial hyperplasia 5 per cent (15/298). Pigs at least six years of age were statistically more likely to have a uterine lesion (less than P=0.001). Smooth muscle tumours represented the most frequent neoplasm. Haemorrhage was the most common intraoperative complication in 23 per cent (8/34) of pigs with neoplasia. Pigs without reproductive tract lesions were statistically more likely to survive to hospital discharge than those with lesions (P=0.001). Short-term survival, defined as survival to hospital discharge, of pigs with reproductive tract lesions was 89 per cent (48/54). Pigs with pyometra were least likely to survive to discharge 60 per cent (3/5). Long-term survival (≥1 year) was 93 per cent (14/15) for pigs with neoplasia. Practitioners should be aware of significantly higher rate of neoplastic and inflammatory diseases in PBP at least six years of age. To minimise morbidity and mortality in PBP undergoing OVH, the present study suggests the procedure should be performed prior to six years of age.

[1]  S. Withrow,et al.  Withrow & Macewen's Small Animal Clinical Oncology , 2019 .

[2]  J. Lawrence,et al.  Tumors of the Female Reproductive System , 2019, Withrow and MacEwen's Small Animal Clinical Oncology.

[3]  K. Thompson,et al.  ANTEMORTEM DIAGNOSIS OF CYSTIC ENDOMETRIAL HYPERPLASIA AND SUCCESSFUL OVARIOHYSTERECTOMY IN AN AFRICAN WARTHOG (PHACOCHOERUS AFRICANUS) , 2015, Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.

[4]  M. Ribeiro,et al.  Trueperella pyogenes multispecies infections in domestic animals: a retrospective study of 144 cases (2002 to 2012) , 2015, The Veterinary quarterly.

[5]  Margaret A. Miller,et al.  Pathology in practice. Myometrial leiomyoma in a Vietnamese potbellied pig. , 2014, Journal of the American Veterinary Medical Association.

[6]  H. Sakai,et al.  Choriocarcinoma-like tumor in a potbellied pig (Sus scrofa) , 2014, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

[7]  D. Hendrickson,et al.  Turner and McIlwraith's Techniques in Large Animal Surgery , 2013 .

[8]  A. Biedrzycki,et al.  A less invasive technique for spaying pet pigs. , 2013, Veterinary surgery : VS.

[9]  M. Chaffin,et al.  Abdominal abscesses in adult horses: 61 cases (1993-2008). , 2012, Journal of the American Veterinary Medical Association.

[10]  A. Egenvall,et al.  Breed variations in the incidence of pyometra and mammary tumours in Swedish dogs. , 2012, Reproduction in domestic animals = Zuchthygiene.

[11]  J. Zimmerman.  Diseases of swine , 2012 .

[12]  S. Johnston,et al.  Veterinary Surgery: Small Animal , 2012 .

[13]  J. Kirpensteijn,et al.  Comparison of surgical variables and short-term postoperative complications in healthy dogs undergoing ovariohysterectomy or ovariectomy. , 2011, Journal of the American Veterinary Medical Association.

[14]  A. Panitch,et al.  Abdominal adhesions: current and novel therapies. , 2011, The Journal of surgical research.

[15]  B. Rohrbach,et al.  Uterine Lesions in 32 Female Miniature Pet Pigs , 2010, Veterinary pathology.

[16]  G. Campbell,et al.  Successful treatment of a Vietnamese potbellied pig with an ovarian leiomyoma. , 2010, Journal of the American Veterinary Medical Association.

[17]  W. Kuller,et al.  Neoplasms of the genital tract in a Vietnamese potbellied pig. , 2010, Tijdschrift voor diergeneeskunde.

[18]  I. Reichler,et al.  Gonadectomy in cats and dogs: a review of risks and benefits. , 2009, Reproduction in domestic animals = Zuchthygiene.

[19]  D. Schlafer,et al.  Cystic endometrial hyperplasia, pseudo-placentational endometrial hyperplasia, and other cystic conditions of the canine and feline uterus. , 2008, Theriogenology.

[20]  W. Sipos,et al.  Minipigs and potbellied pigs as pets in the veterinary practice--a retrospective study. , 2007, Journal of veterinary medicine. A, Physiology, pathology, clinical medicine.

[21]  L. Howe.  Surgical methods of contraception and sterilization. , 2006, Theriogenology.

[22]  T. Suzuki,et al.  Uterine leiomyoma versus leiomyosarcoma: a new attempt at differential diagnosis based on their cellular characteristics , 2006, Histopathology.

[23]  Frances O Smith.  Canine pyometra. , 2006, Theriogenology.

[24]  J. Munday,et al.  Diffuse Cystic Endometrial Hyperplasia and Metastatic Endometrial Adenocarcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa) , 2004, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

[25]  D. Dixon,et al.  Uterine Smooth Muscle Tumors in Potbellied Pigs (Sus scrofa) Resemble Human Fibroids: A Potential Animal Model , 2004, Toxicologic pathology.

[26]  S. Fubini,et al.  Farm animal surgery. , 2004 .

[27]  P. Mueller,et al.  Prevention and treatment of gastrointestinal adhesions. , 2003, The Veterinary clinics of North America. Equine practice.

[28]  J. Ramos-Vara,et al.  Uterine Neoplasia in 13 Cats , 2003, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

[29]  J. Munday,et al.  Uterine Leiomyomas in Two Vietnamese Pot-bellied Pigs (Sus scrofa) , 2002, Veterinary pathology.

[30]  D. Meuten.  Tumors in Domestic Animals: Meuten/Tumors , 2002 .

[31]  L. Hodges,et al.  Uterine Leiomyomas: Mechanisms of Tumorigenesis , 2001, Toxicologic pathology.

[32]  T. Fossum,et al.  Long-term outcome of gonadectomy performed at an early age or traditional age in cats. , 2000, Journal of the American Veterinary Medical Association.

[33]  V. Tynes.  Preventive health care for pet potbellied pigs. , 1999, The veterinary clinics of North America. Exotic animal practice.

[34]  D. V. Van Metre,et al.  Miniature pigs. , 1999, The veterinary clinics of North America. Exotic animal practice.

[35]  Darcy H. Shaw,et al.  Small Animal Internal Medicine , 2019 .

[36]  A. de Kruif,et al.  Influence of the oestrous cycle on experimental intrauterine E. coli infection in the sow. , 1994, Zentralblatt fur Veterinarmedizin. Reihe A.

[37]  Bradley Rl,et al.  Pyometra in cats: 183 cases (1979-1984). , 1987 .

[38]  D. Matthiesen,et al.  Pyometra in cats: 183 cases (1979-1984). , 1987, Journal of the American Veterinary Medical Association.

[39]  J. Akkermans,et al.  Tumors and tumor-like lesions in the genitalia of sows. , 1984, The Veterinary quarterly.

[40]  F. Torday.  The spaying of pigs. Ovaro-hysterectomy or ovariotomy. , 1975, Acta veterinaria Academiae Scientiarum Hungaricae.

[41]  K. von Winterfeldt.  [Leiomyoma in the broad ligament of the uterus of a pig]. , 1964, Deutsche tierarztliche Wochenschrift.

[42]  M. A. Weinberger.  Tumors in Domestic Animals , 1962 .

[43]  J. Moulton.  Tumors in domestic animals , 1961 .

[44]  J. Mcarthur.  Diseases of the reproductive system. , 1952, Annual review of medicine.