Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization toward higher-order oligomers

[1]  M. Heilemann,et al.  Receptor-ligand interactions: binding affinities studied by single-molecule and super-resolution microscopy on intact cells. , 2014, Chemphyschem : a European journal of chemical physics and physical chemistry.

[2]  U. Endesfelder,et al.  A simple method to estimate the average localization precision of a single-molecule localization microscopy experiment , 2014, Histochemistry and Cell Biology.

[3]  H. Sudhoff,et al.  1,8-Cineol inhibits nuclear translocation of NF-κB p65 and NF-κB-dependent transcriptional activity. , 2013, Biochimica et biophysica acta.

[4]  Wendell A. Lim,et al.  Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory , 2013, Proceedings of the National Academy of Sciences.

[5]  A. Herrmann,et al.  Antagonistic TNF Receptor One-Specific Antibody (ATROSAB): Receptor Binding and In Vitro Bioactivity , 2013, PloS one.

[6]  Mike Heilemann,et al.  Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells , 2013, BMC biophysics.

[7]  P. Bork,et al.  Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines , 2013, Molecular systems biology.

[8]  M. Heilemann,et al.  Super-Resolution Microscopy Reveals Specific Recruitment of HIV-1 Envelope Proteins to Viral Assembly Sites Dependent on the Envelope C-Terminal Tail , 2013, PLoS pathogens.

[9]  M. Sauer,et al.  rapidSTORM: accurate, fast open-source software for localization microscopy , 2012, Nature Methods.

[10]  Adrian Whitty,et al.  Binding efficiency of protein-protein complexes. , 2012, Biochemistry.

[11]  C. Bustamante,et al.  Counting single photoactivatable fluorescent molecules by photoactivated localization microscopy (PALM) , 2012, Proceedings of the National Academy of Sciences.

[12]  Daniel Choquet,et al.  TNF-α influences the lateral dynamics of TNF receptor I in living cells. , 2012, Biochimica et biophysica acta.

[13]  Sebastian Malkusch,et al.  Single-molecule coordinate-based analysis of the morphology of HIV-1 assembly sites with near-molecular spatial resolution , 2012, Histochemistry and Cell Biology.

[14]  J. Sachs,et al.  TNFR1 signaling is associated with backbone conformational changes of receptor dimers consistent with overactivation in the R92Q TRAPS mutant. , 2012, Biochemistry.

[15]  Joerg Bewersdorf,et al.  Optical nanoscopy: from acquisition to analysis. , 2012, Annual review of biomedical engineering.

[16]  P. Scheurich,et al.  A minimal mathematical model for the initial molecular interactions of death receptor signalling. , 2012, Mathematical biosciences and engineering : MBE.

[17]  Paul D. Dunne,et al.  Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast , 2012, Open Biology.

[18]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[19]  David D. Thomas,et al.  Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized* , 2012, The Journal of Biological Chemistry.

[20]  J. Sibarita,et al.  TNF-alpha alpha influences the lateral dynamics of TNF receptor I in living cells , 2012 .

[21]  P. Verveer,et al.  Coordinate-based colocalization analysis of single-molecule localization microscopy data , 2011, Histochemistry and Cell Biology.

[22]  Prabuddha Sengupta,et al.  Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis , 2011, Nature Methods.

[23]  Dieter Braun,et al.  Molecular interaction studies using microscale thermophoresis. , 2011, Assay and drug development technologies.

[24]  P. Annibale,et al.  Quantitative Photo Activated Localization Microscopy: Unraveling the Effects of Photoblinking , 2011, PloS one.

[25]  Peter Scheurich,et al.  TNFR1‐induced activation of the classical NF‐κB pathway , 2011, The FEBS journal.

[26]  Peter J. Verveer,et al.  Chemically Induced Photoswitching of Fluorescent Probes—A General Concept for Super-Resolution Microscopy , 2011, Molecules.

[27]  James R Faeder,et al.  Efficient modeling, simulation and coarse-graining of biological complexity with NFsim , 2011, Nature Methods.

[28]  P. Vandenabeele,et al.  Molecular mechanisms of necroptosis: an ordered cellular explosion , 2010, Nature Reviews Molecular Cell Biology.

[29]  Peter Scheurich,et al.  Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2. , 2010, Cellular signalling.

[30]  D. Braun,et al.  Optical thermophoresis for quantifying the buffer dependence of aptamer binding. , 2010, Angewandte Chemie.

[31]  D. Mann,et al.  Oxidative Stress Promotes Ligand-independent and Enhanced Ligand-dependent Tumor Necrosis Factor Receptor Signaling* , 2008, Journal of Biological Chemistry.

[32]  F. Chan,et al.  Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling. , 2007, Cytokine.

[33]  Dieter Braun,et al.  Why molecules move along a temperature gradient , 2006, Proceedings of the National Academy of Sciences.

[34]  G. Soma,et al.  A soluble 17 kDa tumour necrosis factor (TNF) mutein, TNF-SAM2, with membrane-bound TNF-like biological characteristics. , 2006, Anticancer research.

[35]  M. Elvers,et al.  Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling , 2006, BMC Neuroscience.

[36]  J. Lippincott-Schwartz,et al.  Imaging Intracellular Fluorescent Proteins at Nanometer Resolution , 2006, Science.

[37]  Yeon-Woo Ryu,et al.  Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors. , 2005, Biochemical and biophysical research communications.

[38]  H. Wajant,et al.  The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability , 2005, The Journal of cell biology.

[39]  M. Sarker,et al.  SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. , 2004, The Journal of cell biology.

[40]  D. Kabelitz,et al.  Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. , 2004, Immunity.

[41]  Trachette L. Jackson,et al.  A mathematical model of receptor-mediated apoptosis: dying to know why fasl is a trimer. , 2004, Mathematical biosciences and engineering : MBE.

[42]  Peter Scheurich,et al.  Control of Receptor-induced Signaling Complex Formation by the Kinetics of Ligand/Receptor Interaction* , 2002, The Journal of Biological Chemistry.

[43]  David G Spiller,et al.  Multi-parameter analysis of the kinetics of NF-kappaB signalling and transcription in single living cells. , 2002, Journal of cell science.

[44]  D. MacEwan.  TNF ligands and receptors – a matter of life and death , 2002, British journal of pharmacology.

[45]  Eric Jones,et al.  SciPy: Open Source Scientific Tools for Python , 2001 .

[46]  R M Siegel,et al.  A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. , 2000, Science.

[47]  M. Ultsch,et al.  Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5. , 1999, Molecular cell.

[48]  Robert Presley,et al.  Evolutionary biology: Pelvic problems for mammals , 1997, Nature.

[49]  Jennifer Lippincott-Schwartz,et al.  ER-to-Golgi transport visualized in living cells , 1997, Nature.

[50]  George Kollias,et al.  The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor , 1995, Cell.

[51]  S R Sprang,et al.  Crystallographic Evidence for Dimerization of Unliganded Tumor Necrosis Factor Receptor (*) , 1995, The Journal of Biological Chemistry.

[52]  P. Zagouras,et al.  Dynamic equilibrium between vesicular stomatitis virus glycoprotein monomers and trimers in the Golgi and at the cell surface , 1993, Journal of virology.

[53]  D. Banner,et al.  Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation , 1993, Cell.

[54]  H. Schoenfeld,et al.  Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[55]  S. Sprang,et al.  The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. , 1990, The Journal of biological chemistry.

[56]  H. Hohmann,et al.  Two different cell types have different major receptors for human tumor necrosis factor (TNF alpha). , 1989, The Journal of biological chemistry.

[57]  P. Cuatrecasas,et al.  Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity. , 1985, Proceedings of the National Academy of Sciences of the United States of America.