论文信息 - Using Raman spectroscopy to estimate the demineralization of bone transplants during preparation

Using Raman spectroscopy to estimate the demineralization of bone transplants during preparation

This paper presents the results of experimental studies of samples of human cortical and spongy bone tissue by means of Raman scattering as a function of the degree of demineralization. Raman spectra are obtained for samples of human cortical and spongy bone tissue as a function of the degree of demineralization. The dependence of the intensity ratio on the demineralization time, which characterizes the degree of demineralization, is studied for the Raman peaks at 950–962 (PO4)3− and 1665 cm−1 (amide I).

[1] Suk-Ja Yoon,et al. Comparison of the bone healing capacity of autogenous bone, demineralized freeze dried bone allograft, and collagen sponge in repairing rabbit cranial defects , 2012 .

[2] Charles DiMarzio,et al. Combining multispectral polarized light imaging and confocal microscopy for localization of nonmelanoma skin cancer. , 2005, Journal of biomedical optics.

[3] D. McLean,et al. Automated Autofluorescence Background Subtraction Algorithm for Biomedical Raman Spectroscopy , 2007, Applied Spectroscopy.

[4] P. Torzilli,et al. Fourier transform infrared imaging spectroscopy analysis of collagenase-induced cartilage degradation. , 2005, Journal of biomedical optics.

[5] D. Jacob,et al. Amorphous, nanocrystalline and crystalline calcium carbonates in biological materials , 2011 .

[6] C. Gabrielli,et al. Characterization of CaCO3 hydrates by micro‐Raman spectroscopy , 2002 .

[7] C. Misch,et al. BONE‐GRAFTING MATERIALS IN IMPLANT DENTISTRY , 1993, Implant dentistry.

[8] G Penel,et al. Composition of bone and apatitic biomaterials as revealed by intravital Raman microspectroscopy. , 2005, Bone.

[9] Michael D. Morris,et al. Recent developments in Raman and infrared spectroscopy and imaging of bone tissue , 2004 .

[10] Jan Greve,et al. Applications of Micro-Raman Imaging in Biomedical Research , 1997 .