Transitional carcinoma of the upper urinary tract: a histological and cytopathological study.

A histological and cytopathological study of 54 patients with transitional carcinoma of the upper urinary tract was undertaken. There were 17 patients with grade 1 tumours, 35 with grades 2 or 3, and two with carcinoma in situ. Only 16 had non-invasive tumours. A preoperative cytological diagnosis of tumour was made in 67% of the group as a whole and in 75% of patients with grade 2 or 3 tumours. Seventy per cent of voided urines and 80% of ileal conduit urines were positive for tumour. Cytological grading correlated with histology in 12 of 14 grade 1 tumours and 26 of 35 grade 2 or 3 tumours, with seven assigned grade 1. Two cases of pelvicalycine carcinoma in situ were graded 3 by cytology. Cytological investigation by those experienced in urinary cytology has an important diagnostic contribution to make in transitional carcinoma of the upper urinary tract.

[1]  C. Horne,et al.  Deficiency of serum "pregnancy-associated" alpha 2-glycoprotein alpha 2-PAG): association with disease. , 1986, Journal of clinical pathology.

[2]  W M Murphy,et al.  Urinary cytology and bladder cancer. The cellular features of transitional cell neoplasms , 1984, Cancer.

[3]  M. Boon,et al.  Analysis of the performance of pathologists in the grading of bladder tumors. , 1983, Human pathology.

[4]  R. Nelson.  New concepts in staging and follow-up of bladder carcinoma. , 1983, Urology.

[5]  F. Hering,et al.  Value of exfoliative urinary cytology for differentiation between uric acid stone and tumor of upper urinary tract. , 1982, Urology.

[6]  E. Wilson,et al.  Urine cytology in patients with calculi. , 1982, Journal of clinical pathology.

[7]  S. Karlsen.  Improved technique for retrograde brushing in diagnosis of urothelial tumors of upper urinary tract. , 1981, Urology.

[8]  C. Booth,et al.  Urothelial carcinoma of the kidney and ureter. , 1980, British journal of urology.

[9]  G. Prout,et al.  Positive urinary cytology in patients without evident tumor. , 1977, The Journal of urology.

[10]  W. Murphy,et al.  Cytology in the diagnosis and followup of transitional cell carcinoma of the urothelium: a review with a case series. , 1976, The Journal of urology.

[11]  M. Bibbo,et al.  Evaluation of renal masses including retrograde renal brushing. , 1976, The Surgical clinics of North America.

[12]  M. Melamed,et al.  Urinary conduit cytology , 1973, Cancer.

[13]  P. Esposti,et al.  Grading of transitional cell neoplasms of the urinary bladder from smears of bladder washings. A critical review of 326 tumors. , 1972, Acta cytologica.

[14]  Straffon Wg.  Cytology of bladder cancer. , 1972 .

[15]  W. Straffon.  Cytology of bladder cancer. , 1972, British journal of urology.