CD3 components at the surface of pro‐T cells can mediate pre‐T cell development in vivo

Developmentally arrested pro‐T cells (CD4−8−, IL‐2R+, HSA++) of RAG‐1‐deficient mice appear to express low levels of CD3 molecules in the absence of T cell receptor (TcR) chains at their surface, while developmentally arrested pre‐T cells of TcRα‐deficient mice express low levels of a disulfide‐linked TcRβ chain in association with CD3 molecules.

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