Domain flexibility in aspartic proteinases
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T L Blundell | D S Moss | A Sali | T. Blundell | A. Sali | D. Moss | J. Cooper | T. Hofmann | B. Veerapandian | J B Cooper | B Veerapandian | T. Hofmann | T Hofmann
[1] V. Antonov,et al. Mechanism of pepsin catalysis: General base catalysis by the active‐site carboxylate ion , 1978, FEBS letters.
[2] B. L. Sibanda,et al. Inhibitors of aspartic proteinases and their relevance to the design of antihypertensive agents. , 1987, Biochemical Society transactions.
[3] V K Antonov,et al. Studies on the mechanisms of action of proteolytic enzymes using heavy oxygen exchange. , 2005, European journal of biochemistry.
[4] Tom Blundell,et al. The active site of aspartic proteinases , 1991, FEBS letters.
[5] F. Richards,et al. Identification of structural motifs from protein coordinate data: Secondary structure and first‐level supersecondary structure * , 1988, Proteins.
[6] A. Fedorov,et al. Structure of ethanol-inhibited porcine pepsin at 2-A resolution and binding of the methyl ester of phenylalanyl-diiodotyrosine to the enzyme. , 1984, The Journal of biological chemistry.
[7] G. Cohen,et al. Structure and refinement at 1.8 A resolution of the aspartic proteinase from Rhizopus chinensis. , 1987, Journal of molecular biology.
[8] J. Knowles,et al. Acyl- and amino-transfer routes in pepsin-catalyzed reactions , 1975 .
[9] T. N. Palmer,et al. The action pattern of amylomaltase , 1968, FEBS Letters.
[10] D. Davies,et al. Three-dimensional structure of the complex of the Rhizopus chinensis carboxyl proteinase and pepstatin at 2.5-A resolution. , 1982, Biochemistry.
[11] L. Polgár. The mechanism of action of aspartic proteases involves ‘push‐pull’ catalysis , 1987, FEBS letters.
[12] Activation of the action of penicillopepsin on leucyl-tyrosyl-amide by a non-substrate peptide and evidence for a conformational change associated with a secondary binding site. , 1974, Biochemical and biophysical research communications.
[13] T. Blundell,et al. X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin. , 1994, Journal of molecular biology.
[14] A. Cunningham,et al. Effect of secondary substrate binding in penicillopepsin: contributions of subsites S3 and S2' to kcat. , 1988, Biochemistry.
[15] S. James,et al. Enzyme-catalyzed condensation reactions which initiate rapid peptic cleavage of substrates. 2. Proof of mechanism for three examples. , 1981, Biochemistry.
[16] E. Padlan,et al. Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[17] M. James,et al. Molecular structure of an aspartic proteinase zymogen, porcine pepsinogen, at 1.8 Å resolution , 1986, Nature.
[18] M. James,et al. Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 Å and sequence homology with porcine pepsin , 1977, Nature.
[19] James A. Ibers,et al. International tables for X-ray crystallography , 1962 .
[20] K. N. Trueblood,et al. On the rigid-body motion of molecules in crystals , 1968 .
[21] A. Cunningham,et al. Penicillopepsin, the aspartic proteinase from Penicillium janthinellum: substrate-binding effects and intermediates in transpeptidation reactions. , 1985, Biochemical Society transactions.
[22] W. Worth. Distribution of Plasma Fatty Acid before and after Canine Hepatic Homograft , 1968, Nature.
[23] R. Hodges,et al. Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin. , 1984, Biochemistry.
[24] L. Pearl,et al. The catalytic mechanism of aspartic proteinases , 1987, FEBS letters.
[25] A. Wlodawer,et al. The three‐dimensional structure of recombinant bovine chymosin at 2.3 Å resolution , 1990, Proteins.
[26] J Cooper,et al. The structure of a synthetic pepsin inhibitor complexed with endothiapepsin. , 1987, European journal of biochemistry.
[27] T. Blundell,et al. The high resolution structure of endothiapepsin , 1985 .
[28] J D Baxter,et al. Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. , 1989, Science.
[29] T L Blundell,et al. On the rational design of renin inhibitors: X-ray studies of aspartic proteinases complexed with transition-state analogues. , 1987, Biochemistry.
[30] D S Moss,et al. Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model. , 1989, Acta crystallographica. Section A, Foundations of crystallography.
[31] T. Blundell,et al. High‐resolution X‐ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme. , 1989, The EMBO journal.
[32] G J Williams,et al. The Protein Data Bank: a computer-based archival file for macromolecular structures. , 1977, Journal of molecular biology.
[33] T. L. Blundell,et al. High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes , 1987, Nature.
[34] T. Blundell,et al. Definition of general topological equivalence in protein structures. A procedure involving comparison of properties and relationships through simulated annealing and dynamic programming. , 1990, Journal of molecular biology.
[35] T. Blundell,et al. X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution. , 1990, Journal of molecular biology.
[36] M. James,et al. Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[37] T L Blundell,et al. X-ray studies of aspartic proteinase-statine inhibitor complexes. , 1991, Biochemistry.
[38] D. Davies,et al. The structure and function of the aspartic proteinases. , 1990 .
[39] Frederic M. Richards,et al. Packing of α-helices: Geometrical constraints and contact areas☆ , 1978 .
[40] T. L. Blundell,et al. Structural evidence for gene duplication in the evolution of the acid proteases , 1978, Nature.
[41] L. Mazzarella,et al. Structure and function of haemoglobin: IV. A three-dimensional Fourier synthesis of horse deoxyhaemoglobin at 5.5 Å resolution , 1967 .
[42] B. Dunn,et al. Cryoenzymology of penicillopepsin; with an appendix: mechanism of action of aspartyl proteinases. , 1984, Biochemistry.
[43] M. James,et al. Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin. , 1985, Biochemistry.
[44] W. Kabsch,et al. Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features , 1983, Biopolymers.
[45] M. James,et al. Structure and refinement of penicillopepsin at 1.8 A resolution. , 1983, Journal of molecular biology.
[46] D. Rich,et al. Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effect of structure in subsite P3 on inhibition of pepsin. , 1982, Journal of medicinal chemistry.
[47] David S. Moss,et al. Restrained structure-factor least-squares refinement of protein structures using a vector processing computer , 1985 .
[48] T. T. Wang,et al. Acyl intermediates in pepsin and penicillopepsin catalyzed reactions. , 1974, Biochemical and biophysical research communications.