Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

[1]  Alejo E. Rodriguez-Fraticelli,et al.  The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis , 2010, The Journal of cell biology.

[2]  Yi Hao,et al.  Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation , 2010, The Journal of cell biology.

[3]  D. St Johnston,et al.  aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells , 2010, Cell.

[4]  Jing Liu,et al.  LGN regulates mitotic spindle orientation during epithelial morphogenesis , 2010, The Journal of cell biology.

[5]  C. Doe,et al.  Identification of an Aurora-A/PinsLINKER/ Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells , 2009, Cell.

[6]  I. Macara,et al.  The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. , 2009, Genes & development.

[7]  A. Suzuki,et al.  Interaction between PAR-3 and the aPKC–PAR-6 complex is indispensable for apical domain development of epithelial cells , 2009, Journal of Cell Science.

[8]  Chris Q. Doe,et al.  Spindle orientation during asymmetric cell division , 2009, Nature Cell Biology.

[9]  A. Hall,et al.  Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis , 2008, The Journal of cell biology.

[10]  K. Mostov,et al.  From cells to organs: building polarized tissue , 2008, Nature Reviews Molecular Cell Biology.

[11]  P. Gönczy.  Mechanisms of asymmetric cell division: flies and worms pave the way , 2008, Nature Reviews Molecular Cell Biology.

[12]  J. Knoblich,et al.  Mechanisms of Asymmetric Stem Cell Division , 2008, Cell.

[13]  Kristie L. Rose,et al.  Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry , 2008, Nature Protocols.

[14]  Bob Goldstein,et al.  The PAR proteins: fundamental players in animal cell polarization. , 2007, Developmental cell.

[15]  C. Doe,et al.  Gαi generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts , 2007, Proceedings of the National Academy of Sciences.

[16]  Y. Jan,et al.  Drosophila Neuroblast Asymmetric Cell Division: Recent Advances and Implications for Stem Cell Biology , 2006, Neuron.

[17]  I. Macara,et al.  Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly , 2006, The Journal of cell biology.

[18]  C. Doe,et al.  Microtubule-Induced Pins/Gαi Cortical Polarity in Drosophila Neuroblasts , 2005, Cell.

[19]  I. Macara,et al.  Par-3 controls tight junction assembly through the Rac exchange factor Tiam1 , 2005, Nature Cell Biology.

[20]  I. Macara,et al.  Mammalian Pins Is a Conformational Switch that Links NuMA to Heterotrimeric G Proteins , 2004, Cell.

[21]  E. Nishida,et al.  The polarity‐inducing kinase Par‐1 controls Xenopus gastrulation in cooperation with 14‐3‐3 and aPKC , 2004, The EMBO journal.

[22]  Anthony A Hyman,et al.  Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. , 2004, Annual review of cell and developmental biology.

[23]  A. Suzuki,et al.  aPKC Acts Upstream of PAR-1b in Both the Establishment and Maintenance of Mammalian Epithelial Polarity , 2004, Current Biology.

[24]  D. Siderovski,et al.  Return of the GDI: the GoLoco motif in cell division. , 2004, Annual review of biochemistry.

[25]  H. Piwnica-Worms,et al.  Atypical PKC Phosphorylates PAR-1 Kinases to Regulate Localization and Activity , 2004, Current Biology.

[26]  T. Takeda.  Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Na+/H+-exchanger regulatory factor 2 and ezrin , 2003, Journal of Clinical and Experimental Nephrology.

[27]  W. Nelson,et al.  Adaptation of core mechanisms to generate cell polarity , 2003, Nature.

[28]  Yong Li,et al.  PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2. , 2002, American journal of physiology. Renal physiology.

[29]  J. Knoblich,et al.  Heterotrimeric G Proteins Direct Two Modes of Asymmetric Cell Division in the Drosophila Nervous System , 2001, Cell.

[30]  Keith E. Mostov,et al.  Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly , 2001, Nature Cell Biology.

[31]  L. Orci,et al.  Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors , 1991, Cell.