论文信息 - Scale-rich metabolic networks.

Scale-rich metabolic networks.

Recent research in biology has clarified many features of the global organization of metabolic networks, including the biochemical mechanisms responsible for power laws in metabolite degrees. The primary aim of this Letter is to give the simplest possible biochemical explanations and minimal toy models based on a highly optimized tolerance perspective, which show where and why metabolic networks have power laws. A second aim is to further explain why scale-free explanations fail in this case to correctly describe metabolism.

R. Tanaka | Reiko Tanaka

[1] Benoit B. Mandelbrot,et al. Fractals and Scaling in Finance , 1997 .

[2] Doyle,et al. Highly optimized tolerance: robustness and design in complex systems , 2000, Physical review letters.

[3] John Doyle,et al. Complexity and robustness , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[4] J. Doyle,et al. Reverse Engineering of Biological Complexity , 2002, Science.

[5] An-Ping Zeng,et al. The Connectivity Structure, Giant Strong Component and Centrality of Metabolic Networks , 2003, Bioinform..

[6] Sergey N. Dorogovtsev,et al. Evolution of Networks: From Biological Nets to the Internet and WWW (Physics) , 2003 .

[7] J. Doyle,et al. Bow Ties, Metabolism and Disease , 2022 .

[8] Masanori Arita. The metabolic world of Escherichia coli is not small. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[9] A. Barabasi,et al. Network biology: understanding the cell's functional organization , 2004, Nature Reviews Genetics.

[10] Albert-László Barabási,et al. Evolution of Networks: From Biological Nets to the Internet and WWW , 2004 .