The scope of receptor editing and its association with autoimmunity.

[1]  S. Avrameas,et al.  Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens. , 1983, Journal of immunology.

[2]  J. Dangl,et al.  Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma , 1986, Nature.

[3]  M. Reth,et al.  A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production , 1986, Nature.

[4]  R. Hardy,et al.  Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice , 1991, Nature.

[5]  M. Radic,et al.  Ig H and L chain contributions to autoimmune specificities. , 1991, Journal of immunology.

[6]  S. Camper,et al.  Receptor editing: an approach by autoreactive B cells to escape tolerance , 1993, The Journal of experimental medicine.

[7]  J Erikson,et al.  B lymphocytes may escape tolerance by revising their antigen receptors , 1993, The Journal of experimental medicine.

[8]  D. Nemazee,et al.  Receptor editing in self-reactive bone marrow B cells , 1993, The Journal of experimental medicine.

[9]  M. Radic,et al.  Genetic and structural evidence for antigen selection of anti-DNA antibodies. , 1994, Annual review of immunology.

[10]  D. Baltimore,et al.  Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. , 1994, Genes & development.

[11]  R. Hardy,et al.  Deletion and editing of B cells that express antibodies to DNA. , 1994, Journal of immunology.

[12]  E. L. Prak,et al.  Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance , 1994, The Journal of experimental medicine.

[13]  K. Rajewsky,et al.  Rearrangement of upstream DH and VH genes to a rearranged immunoglobulin variable region gene inserted into the DQ52‐JH region of the immunoglobulin heavy chain locus , 1995, European journal of immunology.

[14]  E. Selsing,et al.  Immunoglobulin λ genes , 1995 .

[15]  E. L. Prak,et al.  Light chain replacement: a new model for antibody gene rearrangement , 1995, The Journal of experimental medicine.

[16]  E. L. Prak,et al.  Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. , 1995, Immunity.

[17]  R. Hardy,et al.  The site and stage of anti-DNA B-cell deletion , 1995, Nature.

[18]  M. Wabl,et al.  A Quasi-Monoclonal Mouse , 1996, Science.

[19]  D. Nemazee.  Antigen receptor 'capacity' and the sensitivity of self-tolerance. , 1996, Immunology today.

[20]  L. Wysocki,et al.  T cell recognition and tolerance of antibody diversity. , 1996, Journal of immunology.

[21]  L. Mandik-Nayak,et al.  Regulation of Anti–double-stranded DNA B Cells in Nonautoimmune Mice: Localization to the T–B Interface of the Splenic Follicle , 1997, The Journal of experimental medicine.

[22]  C. Goodnow.  Balancing Immunity, Autoimmunity, and Self‐tolerance a , 1997, Annals of the New York Academy of Sciences.

[23]  K. Rajewsky,et al.  Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. , 1997, Immunity.

[24]  E. L. Prak,et al.  Editing disease-associated autoantibodies. , 1997, Immunity.

[25]  P. Lipsky,et al.  Immunoglobulin kappa chain receptor editing in systemic lupus erythematosus. , 1998, The Journal of clinical investigation.

[26]  F. E. Bertrand,et al.  VH gene replacement occurs in the spleen and bone marrow of non‐autoimmune quasi‐monoclonal mice , 1998, European journal of immunology.

[27]  R. Hardy,et al.  Regulation of Anti-DNA B Cells in Recombination-activating Gene–deficient Mice , 1998, The Journal of experimental medicine.

[28]  M. Retter,et al.  Receptor Editing Occurs Frequently during Normal B Cell Development , 1998, The Journal of experimental medicine.

[29]  K. Rajewsky,et al.  B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain. , 1998, Journal of immunology.

[30]  S. Litwin,et al.  Somatic Mutation and Light Chain Rearrangement Generate Autoimmunity in Anti–Single-Stranded DNA Transgenic Mrl/lpr Mice , 1999, The Journal of experimental medicine.

[31]  K. Rajewsky,et al.  Production of high affinity autoantibodies in autoimmune New Zealand Black/New Zealand white F1 mice targeted with an anti-DNA heavy chain. , 1999, Journal of immunology.

[32]  E. Meffre,et al.  Immunoglobulin Heavy Chain Variable Region Gene Replacement as a Mechanism for Receptor Revision in Rheumatoid Arthritis Synovial Tissue B Lymphocytes , 2000, The Journal of experimental medicine.

[33]  K. Rajewsky,et al.  Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[34]  V. Kouskoff,et al.  B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[35]  T. Behrens,et al.  Ig Light Chain Receptor Editing in Anergic B Cells1 , 2000, The Journal of Immunology.

[36]  D. Nemazee.  Receptor selection in B and T lymphocytes. , 2000, Annual review of immunology.

[37]  D. Nemazee,et al.  Revising B Cell Receptors , 2000, The Journal of experimental medicine.

[38]  F. Finkelman,et al.  In Vivo Survival of Autoreactive B Cells: Characterization of Long-Lived B Cells1 , 2000, The Journal of Immunology.

[39]  L. Wysocki,et al.  A Receptor Presentation Hypothesis for T Cell Help That Recruits Autoreactive B Cells1 , 2001, The Journal of Immunology.

[40]  U. Wellmann,et al.  Altered selection processes of B lymphocytes in autoimmune NZB/W mice, despite intact central tolerance against DNA , 2001, European journal of immunology.

[41]  K. Rajewsky,et al.  Contribution of Receptor Editing to the Antibody Repertoire , 2001, Science.

[42]  M. Radic,et al.  Editors and editing of anti-DNA receptors. , 2001, Immunity.

[43]  D. Mason.  Some quantitative aspects of T‐cell repertoire selection: the requirement for regulatory T cells , 2001, Immunological reviews.

[44]  P. Lipsky,et al.  RAG1 and RAG2 Expression by B Cell Subsets from Human Tonsil and Peripheral Blood1 , 2001, The Journal of Immunology.

[45]  K. Rajewsky,et al.  Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human , 2001, European journal of immunology.

[46]  Comment on Langman and Cohn , 2002 .

[47]  R. Jaenisch,et al.  Monoclonal mice generated by nuclear transfer from mature B and T donor cells , 2002, Nature.

[48]  L. Wysocki,et al.  Negligible Class II MHC Presentation of B Cell Receptor-Derived Peptides by High Density Resting B Cells1 , 2002, The Journal of Immunology.

[49]  M. Weigert,et al.  Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern , 2002, The Journal of experimental medicine.

[50]  M. Weigert,et al.  Autoreactive B Cells in the Marginal Zone that Express Dual Receptors , 2002, The Journal of experimental medicine.

[51]  G. Mostoslavsky,et al.  The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status , 2002, European journal of immunology.

[52]  R. Fischel,et al.  Autoimmune NZB/NZW F1 mice utilize B cell receptor editing for generating high‐affinity anti‐dsDNA autoantibodies from low‐affinity precursors , 2003, European journal of immunology.

[53]  H. Stein,et al.  Receptor revision of immunoglobulin heavy chain genes in human MALT lymphomas , 2003, Molecular pathology : MP.

[54]  M. Nussenzweig,et al.  Predominant Autoantibody Production by Early Human B Cell Precursors , 2003, Science.

[55]  M. Weigert,et al.  Secondary Heavy Chain Rearrangement , 2003, The Journal of experimental medicine.

[56]  T. Kepler,et al.  Prospective Estimation of Recombination Signal Efficiency and Identification of Functional Cryptic Signals in the Genome by Statistical Modeling , 2003, The Journal of experimental medicine.

[57]  K. Rajewsky,et al.  Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements , 2003, The Journal of experimental medicine.

[58]  M. Radic,et al.  Regulation of anti-phosphatidylserine antibodies. , 2003, Immunity.

[59]  S. L. Bridges,et al.  Contribution of Vh gene replacement to the primary B cell repertoire. , 2003, Immunity.

[60]  J. Erikson,et al.  The regulation of lupus-associated autoantibodies: immunoglobulin transgenic models. , 2003, Current opinion in immunology.

[61]  D. Gilden,et al.  Single-Cell Repertoire Analysis Demonstrates that Clonal Expansion Is a Prominent Feature of the B Cell Response in Multiple Sclerosis Cerebrospinal Fluid 1 , 2003, The Journal of Immunology.

[62]  Yoram Louzoun,et al.  Editing Anti-DNA B Cells by Vλx , 2004, The Journal of experimental medicine.

[63]  G. Niedobitek,et al.  Rare detection of phenotypically immature lymphocytes in Hashimoto thyroiditis and rheumatoid arthritis. , 2004, Journal of autoimmunity.

[64]  F. Alt,et al.  Receptor revision in T cells: an open question? , 2004, Trends in immunology.

[65]  R. Eisenberg,et al.  Chronic graft‐versus‐host reaction is associated with a decrease in Ig light chain receptor editing in bone marrow self‐reactive B cells , 2004, European journal of immunology.

[66]  T. Gallart,et al.  Transcript Expression of Two Igλ Rearrangements and RAG-1/RAG-2 in a Mature Human B Cell Producing IgMλ Islet Cell Autoantibody , 2003, Journal of Clinical Immunology.

[67]  J. Cyster,et al.  Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. , 2004, Immunity.

[68]  M. Nussenzweig,et al.  Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies , 2004, The Journal of experimental medicine.

[69]  R. Pelanda,et al.  Receptor editing is the main mechanism of B cell tolerance toward membrane antigens , 2004, Nature Immunology.

[70]  M. Nussenzweig,et al.  Human Autoantibody Silencing by Immunoglobulin Light Chains , 2004, The Journal of experimental medicine.

[71]  L. Wysocki,et al.  Activation and Tolerance in CD4+ T Cells Reactive to an Immunoglobulin Variable Region , 2004, The Journal of experimental medicine.

[72]  T. Phan,et al.  Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. , 2004, Immunity.