A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology
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[1] D. Bennett,et al. The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease , 2020, Molecular Psychiatry.
[2] A. Ribeiro-da-Silva,et al. Peripheral and central nervous system alterations in a rat model of inflammatory arthritis. , 2020, Pain.
[3] J. Hort,et al. Sex and gender differences in Alzheimer’s disease: current challenges and implications for clinical practice , 2020, European journal of neurology.
[4] A. Verma,et al. Endothelial stromelysin1 regulation by the forkhead box‐O transcription factors is crucial in the exudative phase of acute lung injury , 2019, Pharmacological research.
[5] A. Cuello,et al. The Brain NGF Metabolic Pathway in Health and in Alzheimer’s Pathology , 2019, Front. Neurosci..
[6] E. Head,et al. Dementia in Down syndrome: unique insights for Alzheimer disease research , 2019, Nature Reviews Neurology.
[7] A. Pastore,et al. The Structure of the Pro-domain of Mouse proNGF in Contact with the NGF Domain. , 2019, Structure.
[8] E. Giacobini,et al. Sex and Gender Differences in the Brain Cholinergic System and in the Response to Therapy of Alzheimer Disease with Cholinesterase Inhibitors. , 2018, Current Alzheimer research.
[9] for the Alzheimer’s Disease Neuroimaging Initiative,et al. Sex differences in Alzheimer disease — the gateway to precision medicine , 2018, Nature Reviews Neurology.
[10] L. F. Aguilar,et al. Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease , 2017, Neurobiology of Disease.
[11] F. Kartberg,et al. Conformational characterization of nerve growth factor-β reveals that its regulatory pro-part domain stabilizes three loop regions in its mature part , 2017, The Journal of Biological Chemistry.
[12] L. Moons,et al. Mechanisms of NMDA Receptor- and Voltage-Gated L-Type Calcium Channel-Dependent Hippocampal LTP Critically Rely on Proteolysis That Is Mediated by Distinct Metalloproteinases , 2017, The Journal of Neuroscience.
[13] P. Bosco,et al. An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation , 2016, Alzheimer's & Dementia.
[14] E. Mufson,et al. Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease. , 2016, Current Alzheimer research.
[15] J. Włodarczyk,et al. Matrix Metalloprotease 3 Activity Supports Hippocampal EPSP-to-Spike Plasticity Following Patterned Neuronal Activity via the Regulation of NMDAR Function and Calcium Flux , 2016, Molecular Neurobiology.
[16] B. de Strooper,et al. Amyloid β Oligomers Disrupt Blood–CSF Barrier Integrity by Activating Matrix Metalloproteinases , 2015, The Journal of Neuroscience.
[17] M. Peng,et al. Plasma gelsolin and matrix metalloproteinase 3 as potential biomarkers for Alzheimer disease , 2015, Neuroscience Letters.
[18] M. Witter,et al. Stereological estimation of neuron number and plaque load in the hippocampal region of a transgenic rat model of Alzheimer's disease , 2015, The European journal of neuroscience.
[19] X. Wang,et al. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease. , 2014, The American journal of pathology.
[20] A. Cuello,et al. Nerve growth factor metabolic dysfunction in Alzheimer's disease and Down syndrome. , 2014, Trends in pharmacological sciences.
[21] W. Klein,et al. Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study , 2014, Acta neuropathologica communications.
[22] Philip S. Insel,et al. Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults , 2014, Neurobiology of Aging.
[23] Ashley M. Fortress,et al. Nerve growth factor metabolic dysfunction in Down's syndrome brains. , 2014, Brain : a journal of neurology.
[24] X. Juanola,et al. Association of biomarkers of inflammation, cartilage and bone turnover with gender, disease activity, radiological damage and sacroiliitis by magnetic resonance imaging in patients with early spondyloarthritis , 2014, Clinical Rheumatology.
[25] R. Midha,et al. Overcoming neurite‐inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix , 2013, Glia.
[26] S. Ball,et al. p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts , 2013, Biochemical and biophysical research communications.
[27] K. Bötzel,et al. Limited cleavage of tau with matrix-metalloproteinase MMP-9, but not MMP-3, enhances tau oligomer formation , 2012, Experimental Neurology.
[28] J. Schneider,et al. Overview and findings from the religious orders study. , 2012, Current Alzheimer research.
[29] C. Kallenberg,et al. Serum MMP-3 Level as a Biomarker for Monitoring and Predicting Response to Etanercept Treatment in Ankylosing Spondylitis , 2011, The Journal of Rheumatology.
[30] M. Folstein,et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS—ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease , 2011, Neurology.
[31] S. Reina,et al. Anti-M(3) muscarinic cholinergic autoantibodies from patients with primary Sjögren's syndrome trigger production of matrix metalloproteinase-3 (MMP-3) and prostaglandin E(2) (PGE(2)) from the submandibular glands. , 2011, Archives of oral biology.
[32] Hee-Sun Kim,et al. α-Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1 , 2010, The Journal of Immunology.
[33] L. Minthon,et al. Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer's disease , 2010, Alzheimer's Research & Therapy.
[34] Claudia Schilling,et al. Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease , 2010, International Psychogeriatrics.
[35] T. Joh,et al. Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress* , 2010, The Journal of Biological Chemistry.
[36] C. Humpel,et al. Matrix metalloproteinases-2 and -3 are reduced in cerebrospinal fluid with low beta-amyloid1–42 levels , 2009, Neuroscience Letters.
[37] J. Wuu,et al. Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment , 2009, Journal of neuropathology and experimental neurology.
[38] A. Cuello,et al. Amyloid &bgr;-Induced Nerve Growth Factor Dysmetabolism in Alzheimer Disease , 2009, Journal of neuropathology and experimental neurology.
[39] A. De Couto Pita,et al. Cholinoceptor modulation on nitric oxide regulates prostaglandin E(2) and metalloproteinase-3 production in experimentally induced inflammation of rat dental pulp. , 2009, Journal of endodontics.
[40] G. Rosenberg,et al. TIMP-3 and MMP-3 contribute to delayed inflammation and hippocampal neuronal death following global ischemia , 2009, Experimental Neurology.
[41] Hee-Sun Kim,et al. Inhibition of MMP‐3 or ‐9 suppresses lipopolysaccharide‐induced expression of proinflammatory cytokines and iNOS in microglia , 2008, Journal of neurochemistry.
[42] T. Joh,et al. A novel intracellular role of matrix metalloproteinase‐3 during apoptosis of dopaminergic cells , 2008, Journal of neurochemistry.
[43] A. Hofman,et al. Matrix metalloproteinase 3 haplotypes and dementia and Alzheimer's disease The Rotterdam Study , 2008, Neurobiology of Aging.
[44] S. Love,et al. MMP‐2, ‐3 and ‐9 levels and activity are not related to Aβ load in the frontal cortex in Alzheimer's disease , 2008, Neuropathology and applied neurobiology.
[45] P. Amouyel,et al. Impact of the matrix metalloproteinase MMP-3 on dementia , 2007, Neurobiology of Aging.
[46] S. Lorenzl,et al. A pivotal role of matrix metalloproteinase‐3 activity in dopaminergic neuronal degeneration via microglial activation , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[47] M. Pizzi,et al. Transplantation of fibroblasts that overexpress matrix metalloproteinase-3 into the site of spinal cord injury in rats. , 2006, Journal of neurotrauma.
[48] D. Aunis,et al. Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance , 2006, International Journal of Developmental Neuroscience.
[49] M. Moscarello,et al. Differences in Susceptibility of MBP Charge Isomers to Digestion by Stromelysin-1 (MMP-3) and Release of an Immunodominant Epitope , 2006, Neurochemical Research.
[50] G. Rosenberg,et al. Blood–brain barrier disruption by stromelysin-1 facilitates neutrophil infiltration in neuroinflammation , 2006, Neurobiology of Disease.
[51] J. Schneider,et al. Neuropathology of older persons without cognitive impairment from two community-based studies , 2006, Neurology.
[52] C. Masters,et al. Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-dependent Up-regulation of Metalloprotease Activity* , 2006, Journal of Biological Chemistry.
[53] A. Cuello,et al. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[54] Mikel L. Olson,et al. Effects of extracellular matrix‐degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity , 2006, Journal of neurochemistry.
[55] G. Rosenberg,et al. Matrix metalloproteinases and free radicals in cerebral ischemia. , 2005, Free radical biology & medicine.
[56] T. Joh,et al. Matrix Metalloproteinase-3: A Novel Signaling Proteinase from Apoptotic Neuronal Cells That Activates Microglia , 2005, The Journal of Neuroscience.
[57] T. Lehtimäki,et al. Interaction between matrix metalloproteinase 3 and the ε4 allele of apolipoprotein E increases the risk of Alzheimer’s disease in Finns , 2004, Neuroscience Letters.
[58] M. Javadi,et al. NF-kappaB binds to a polymorphic repressor element in the MMP-3 promoter. , 2004, Biochemical and biophysical research communications.
[59] M. Moscarello,et al. The Up-regulation of Stromelysin-1 (MMP-3) in a Spontaneously Demyelinating Transgenic Mouse Precedes Onset of Disease* , 2002, The Journal of Biological Chemistry.
[60] M. Malaise,et al. Increased matrix metalloproteinase-3 serum levels in rheumatic diseases: relationship with synovitis and steroid treatment , 2002, Annals of the rheumatic diseases.
[61] Taku Sugawara,et al. Matrix Metalloproteinase Inhibition Prevents Oxidative Stress-Associated Blood–Brain Barrier Disruption after Transient Focal Cerebral Ischemia , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[62] B. Michalski,et al. The Precursor Pro-Nerve Growth Factor Is the Predominant Form of Nerve Growth Factor in Brain and Is Increased in Alzheimer's Disease , 2001, Molecular and Cellular Neuroscience.
[63] M. Esiri,et al. White Matter Damage Is Associated With Matrix Metalloproteinases in Vascular Dementia , 2001, Stroke.
[64] A. Taniguchi,et al. Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritis. , 2000, Arthritis and rheumatism.
[65] T. Hattori,et al. Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer’s disease brain , 2000, Acta Neuropathologica.
[66] P. Libby,et al. Generation of Biologically Active IL-1β by Matrix Metalloproteinases: A Novel Caspase-1-Independent Pathway of IL-1β Processing , 1998, The Journal of Immunology.
[67] A. Cuello,et al. TrkA antagonists decrease NGF-induced ChAT activity in vitro and modulate cholinergic synaptic number in vivo , 1998, Journal of Physiology-Paris.
[68] P. Gottschall,et al. Increased Production of Matrix Metalloproteinases in Enriched Astrocyte and Mixed Hippocampal Cultures Treated with β‐Amyloid Peptides , 1996 .
[69] J. Uitto,et al. Interferon-gamma coordinately upregulates matrix metalloprotease (MMP)-1 and MMP-3, but not tissue inhibitor of metalloproteases (TIMP), expression in cultured keratinocytes. , 1995, The Journal of investigative dermatology.
[70] G. Opdenakker,et al. Cytokine-regulated proteases in autoimmune diseases. , 1994, Immunology today.
[71] A. Cuello,et al. Nerve growth factor-induced synaptogenesis and hypertrophy of cortical cholinergic terminals. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[72] J. Enghild,et al. Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. , 1992, The Journal of biological chemistry.
[73] Y. Okada,et al. Matrix metalloproteinases 1, 2, and 3 from rheumatoid synovial cells are sufficient to destroy joints. , 1987, The Journal of rheumatology.
[74] F. Hefti,et al. Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[75] M. Folstein,et al. Clinical diagnosis of Alzheimer's disease , 1984, Neurology.
[76] T. Powell,et al. Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase , 1983, Brain Research.
[77] R. Bartus,et al. The cholinergic hypothesis of geriatric memory dysfunction. , 1982, Science.
[78] J. Coyle,et al. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. , 1982, Science.
[79] D. Drachman,et al. Human memory and the cholinergic system. A relationship to aging? , 1974, Archives of neurology.
[80] C. Henneberger,et al. Synaptic Potentiation at Basal and Apical Dendrites of Hippocampal Pyramidal Neurons Involves Activation of a Distinct Set of Extracellular and Intracellular Molecular Cues , 2019, Cerebral cortex.
[81] G. Wilcock,et al. Identification and Preliminary Validation of a Plasma Profile Associated with Cognitive Decline in Dementia and At-Risk Individuals: A Retrospective Cohort Analysis. , 2019, Journal of Alzheimer's disease : JAD.
[82] Pitter F. Huesgen,et al. Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses. , 2016, Matrix biology : journal of the International Society for Matrix Biology.
[83] G. Rabinovich,et al. The Role of Galectin-3: From Oligodendroglial Differentiation and Myelination to Demyelination and Remyelination Processes in a Cuprizone-Induced Demyelination Model. , 2016, Advances in experimental medicine and biology.
[84] R. Bernhardi. Glial Cells in Health and Disease of the CNS , 2016, Advances in Experimental Medicine and Biology.
[85] M. Eriksdotter,et al. Analysis of matrix metallo-proteases and the plasminogen system in mild cognitive impairment and Alzheimer's disease cerebrospinal fluid. , 2014, Journal of Alzheimer's disease : JAD.
[86] M. Hasselmo,et al. Modes and Models of Forebrain Cholinergic Neuromodulation of Cognition , 2011, Neuropsychopharmacology.
[87] M. Szyf,et al. A novel transgenic rat model with a full Alzheimer's-like amyloid pathology displays pre-plaque intracellular amyloid-beta-associated cognitive impairment. , 2010, Journal of Alzheimer's disease : JAD.
[88] A. Cuello,et al. Cholinergic Involvement in Alzheimer’s Disease. A Link with NGF Maturation and Degradation , 2009, Journal of Molecular Neuroscience.
[89] M. Mesulam. The cholinergic lesion of Alzheimer's disease: pivotal factor or side show? , 2004, Learning & memory.
[90] T. Robbins,et al. Central cholinergic systems and cognition. , 1997, Annual review of psychology.
[91] A. Cuello,et al. Chapter 32: Trophic responses of forebrain cholinergic neurons: a discussion , 1993 .
[92] G. Paxinos,et al. The Rat Brain in Stereotaxic Coordinates , 1983 .