Cardiotoxicity and antitumor activity of a copper(II)-doxorubicin chelate

[1]  P. Singal,et al.  Subcellular effects of adriamycin in the heart: a concise review. , 1987, Journal of molecular and cellular cardiology.

[2]  G. Batist,et al.  Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action. , 1987, Biochemistry.

[3]  V. Malatesta,et al.  Chelation of copper(II) ions by doxorubicin and 4′-epidoxorubicin: ESR evidence for a new complex at high anthracycline/copper molar ratios , 1987 .

[4]  K. Wallace.  Nonenzymatic oxygen activation and stimulation of lipid peroxidation by doxorubicin-copper. , 1986, Toxicology and applied pharmacology.

[5]  L. Favalli,et al.  Effect of doxorubicin on calcium binding sites in guinea-pig heart. , 1986, Biochemical pharmacology.

[6]  R. Martin.  Tetracyclines and Daunorubicin , 1986 .

[7]  A. Gervasini,et al.  Chelation of copper(ii) ions by doxorubicin and 4'-epidoxorubicin - an electron-spin-resonance study , 1985 .

[8]  J. Zweier.  Iron-mediated formation of an oxidized adriamycin free radical. , 1985, Biochimica et biophysica acta.

[9]  A. Garnier-Suillerot,et al.  Iron(III)-adriamycin and Iron(III)-daunorubicin complexes: physicochemical characteristics, interaction with DNA, and antitumor activity. , 1985, Biochemistry.

[10]  J. Lown,,et al.  Electron paramagnetic resonance characterization and conformation of daunorubicin semiquinone intermediate implicated in anthracycline metabolism, cardiotoxicity, and anticancer action , 1984 .

[11]  A. Martell,et al.  Thermodynamics of oxygen binding in natural and synthetic dioxygen complexes , 1984 .

[12]  B. Carr,et al.  Cell surface-mediated cytotoxicity of polymer-bound Adriamycin against drug-resistant hepatocytes. , 1983, Cancer research.

[13]  L. B. Wingard,et al.  Immobilized adriamycin: a tool for separating cell surface from intracellular mechanisms. , 1983, Federation proceedings.

[14]  J. Peisach,et al.  Structural implications derived from the analysis of electron paramagnetic resonance spectra of natural and artificial copper proteins. , 1974, Archives of biochemistry and biophysics.

[15]  V. Malatesta,et al.  Chelation of copper(II) ions by doxorubicin and 4'-epidoxorubicin: an e.s.r. study. , 1985, Anti-cancer drug design.