Colour discrimination and categorisation in Williams syndrome.

Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample test and a colour naming task. A visual search task was also included as a measure of sensitivity to the size of perceptual colour difference. Results showed that individuals with WS have reduced colour discrimination relative to typically developing participants matched for chronological age; performance was commensurate with a typically developing group matched for non-verbal ability. In contrast, categorisation was typical in WS, although there was some evidence that sensitivity to the size of perceptual colour differences was reduced in this group.

[1]  Jon Driver,et al.  Visual search in typically developing toddlers and toddlers with Fragile X or Williams syndrome. , 2004, Developmental science.

[2]  Paul T. Sowden,et al.  Color Perception in Children with Autism , 2008, Journal of autism and developmental disorders.

[3]  M. Bornstein,et al.  Chromatic information processing: Rate depends on stimulus location in the category and psychological complexity , 1980 .

[4]  J. Sergeant,et al.  Colour perception in ADHD. , 2006, Journal of child psychology and psychiatry, and allied disciplines.

[5]  J. Atkinson,et al.  Visual and visuospatial development in young children with Williams syndrome , 2001, Developmental medicine and child neurology.

[6]  V C Smith,et al.  Color-axis determination on the Farnsworth-Munsell 100-hue test. , 1985, American journal of ophthalmology.

[7]  Paul Koch,et al.  Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome. , 2005, The Journal of clinical investigation.

[8]  Mark H. Johnson,et al.  ERP abnormalities of illusory contour perception in Williams Syndrome , 2003, Neuroreport.

[9]  D C Van Essen,et al.  Information processing in the primate visual system: an integrated systems perspective. , 1992, Science.

[10]  Jonathan E. Jennings,et al.  An fMRI version of the Farnsworth-Munsell 100-Hue test reveals multiple color-selective areas in human ventral occipitotemporal cortex. , 1999, Cerebral cortex.

[11]  Ursula Bellugi,et al.  Reduced parietal and visual cortical activation during global processing in Williams syndrome , 2007, Developmental medicine and child neurology.

[12]  A Sahraie,et al.  New Farnsworth-Munsell 100 hue test norms of normal observers for each year of age 5–22 and for age decades 30–70 , 2002, The British journal of ophthalmology.

[13]  A Uvijls,et al.  A new assessment of the normal ranges of the Farnsworth-Munsell 100-hue test scores. , 1982, American journal of ophthalmology.

[14]  K. Knoblauch,et al.  Variation of chromatic sensitivity across the life span , 2001, Vision Research.

[15]  Paul T. Sowden,et al.  Reduced chromatic discrimination in children with autism spectrum disorders. , 2010, Developmental science.

[16]  A. Baddeley,et al.  Verbal and nonverbal abilities in the Williams syndrome phenotype: evidence for diverging developmental trajectories. , 1998, Journal of child psychology and psychiatry, and allied disciplines.

[17]  J. Enns,et al.  LIFESPAN CHANGES IN ATTENTION: THE VISUAL SEARCH TASK , 1998 .

[18]  D. W. Heeley,et al.  Cardinal directions of color space , 1982, Vision Research.

[19]  Ursula Bellugi,et al.  Williams syndrome: neuronal size and neuronal-packing density in primary visual cortex. , 2002, Archives of neurology.

[20]  C. Jarrold,et al.  Evidence for unusual spatial location coding in Williams syndrome: An explanation for the local bias in visuo-spatial construction tasks? , 2005, Brain and Cognition.

[21]  R. Gunkel,et al.  Color vision and age in a normal North American population , 1991, Graefe's Archive for Clinical and Experimental Ophthalmology.

[22]  G. Orban,et al.  Color discrimination involves ventral and dorsal stream visual areas. , 2004, Cerebral cortex.

[23]  A. Karmiloff-Smith,et al.  Genetic and environmental vulnerabilities in children with neurodevelopmental disorders , 2012, Proceedings of the National Academy of Sciences.

[24]  Andreas Meyer-Lindenberg,et al.  Genetic Contributions to Human Gyrification: Sulcal Morphometry in Williams Syndrome , 2005, The Journal of Neuroscience.

[25]  C. Mervis,et al.  A genetic model for understanding higher order visual processing: functional interactions of the ventral visual stream in Williams syndrome. , 2008, Cerebral cortex.

[26]  Dean Farnsworth,et al.  The Farnsworth-Munsell 100-Hue and Dichotomous Tests for Color Vision* , 1943 .