Morphological Spectrum of Endometrium in Patients Presenting with Dysfunc- tional Uterine Bleeding

Dysfunctional uterine bleeding (DUB) is a clinical term used to describe bleeding not attributable to any underlying organic pathological condition. A total of 187 patients were included in the present study which were categorized in reproductive ( 50yrs) age groups. One hundred sixteen cases (62%) were in reproductive age group, 47 cases (25.1%) in perimenopausa l age group and 24 cases (12.8%) in postmenopausa l age group. Histopathological examination of dilatation and curettage (D&C) samples was done to elucidate the cause of DUB. In reproductive age group, proliferative endometrium was the most common finding (26.8%) followed by irregular maturation (25%).Complex hyperplasia was seen in 6 cases, out of which 1 case showed atypia. Nineteen cases (16.4%) showed associated endometritis. No case of malignancy was observed in this group. In perimenopausal age group, simple hyperplasia was the most frequent finding (29.8%).Complex hyperplasia was seen in 3 cases, out of which 1 revealed atypia. Three cases of malignancy (6.4%) were reported. In postmenopausal age group, most frequent finding in DUB was complex hyperplasia seen in 8 cases (33.3%), out of which 2 cases showed atypia. Six cases (25%) of simple hyperplasia and 4 cases (16.7%) of malignancy were reported. Atrophic endometrium was observed in D&C samples from 6 patients (25%).

[1]  M. Dooley,et al.  Female reproductive system. , 2003 .

[2]  S. Pudasaini,et al.  Histopathological pattern of endometrial samples in abnormal uterine bleeding , 2011 .

[3]  N. Bondagji,et al.  Histopathological Pattern of Endometrial Sampling Performed for Abnormal Uterine Bleeding , 2011 .

[4]  Vinay Kumar,et al.  The Female Genital Tract , 2010 .

[5]  E. Pirog,et al.  The Female Genital Tract , 2010 .

[6]  G. Dangal.  A study of endometrium of patients with abnormal uterine bleeding at Chitwan Valley. , 2003, Kathmandu University medical journal.

[7]  L. Deligdisch.  Hormonal Pathology of the Endometrium , 2000, Modern Pathology.

[8]  Wren Bg.  DYSFUNCTIONAL UTERINE BLEEDING , 1998 .

[9]  B. Wren.  Dysfunctional uterine bleeding. , 1998, Australian family physician.

[10]  L. Mattsson,et al.  Histopathological findings in women with postmenopausal bleeding , 1995, British journal of obstetrics and gynaecology.

[11]  T. Toth,et al.  Abnormal uterine bleeding in the perimenopause. , 1993, International journal of fertility and menopausal studies.

[12]  M. Anderson,et al.  Female Reproductive System , 1991 .

[13]  A. Altchek.  Management of Anovulatory Dysfunctional Uterine Bleeding in the Adolescent , 1991 .

[14]  A. Ferenczy.  Anatomy and Histology of the Uterine Corpus , 1987 .

[15]  R. Kurman,et al.  Benign Diseases of the Endometrium , 1987 .

[16]  M. P. David,et al.  Histopathological Findings in 226 Women with Post‐Menopausal Uterine Bleeding , 1986, Acta obstetricia et gynecologica Scandinavica.