EFFECT OF DIALYSATE TEMPERATURE ON HEMODYNAMIC STABILITY AMONG HEMODIALYSIS PATIENTS

Background Hypotension is one of the complications of hemodialysis treatment. It increases morbidity and mortality and can compromise the dialysis efficacy. Cooling the dialysate below 36.5°C is an important factor that contributes to hemodynamic stability in patients during hemodialysis. Objective To assess the effect of dialysate temperature on hemodynamic stability during hemodialysis sessions, post dialysis fatigue and the adequacy of dialysis. Methods A total of 40 patients were assessed during six dialysis sessions; in three sessions, the dialysate temperature was (37 °C) and in three other sessions, the dialysate temperature was (35 °C). Specific scale questionnaires were used in each dialysis session, to evaluate the symptoms during the dialysis procedure as well as post-dialysis fatigue, and respective scores were noted. Blood pressure, heart rate, temperature were recorded. Also dialysis efficacy using Kt/v, urea reduction ratio were measured. Results The results showed that usage of low dialysate temperature was associated with the following : higher post dialysis systolic blood pressure (P < 0.05) and lower post dialysis heart rate (P < 0.05), better intradialysis symptoms score and post-dialysis fatigue scores (P < 0.05 and P < 0.05, respectively), shorter post-dialysis fatigue period (P < 0.05) as well as Similar urea removal and Kt/V . Conclusion Cool dialysis is an important factor in hemodynamic stability during hemodialysis. Also it improves symptoms during and after hemodialysis. Cool dialysis has no effect on adequacy of dialysis.

[1]  Ahmad Taher Azar,et al.  Effect of dialysate temperature on hemodynamic stability among hemodialysis patients. , 2009, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.

[2]  John M. Johnson,et al.  Body temperature regulation during hemodialysis in long-term patients: is it time to change dialysate temperature prescription? , 2004, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[3]  M. Finlayson,et al.  Effect of cool temperature dialysate on the quality and patients' perception of haemodialysis. , 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[4]  B. Jaber,et al.  A Time for Rediscovery: Chronic Hemofiltration for End‐Stage Renal Disease , 2003, Seminars in dialysis.

[5]  N. Levin,et al.  Heat accumulation with relative blood volume decrease. , 2002, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[6]  F. M. van der Sande,et al.  Energy transfer is the single most important factor for the difference in vascular response between isolated ultrafiltration and hemodialysis. , 2000, Journal of the American Society of Nephrology : JASN.

[7]  F. M. van der Sande,et al.  Strategies for improving hemodynamic stability in cardiac-compromised dialysis patients. , 2000, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[8]  F. M. van der Sande,et al.  Thermal energy balance and body temperature: comparison between isolated ultrafiltration and haemodialysis at different dialysate temperatures. , 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[9]  J. Burema,et al.  Effect of dialysate temperature on energy balance during hemodialysis: quantification of extracorporeal energy transfer. , 1999, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[10]  M. Perazella Review Articles: Approach to Patients with Intradialytic Hypotension: A Focus on Therapeutic Options , 1999 .

[11]  M. Perazella,et al.  Midodrine and cool dialysate are effective therapies for symptomatic intradialytic hypotension. , 1999, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[12]  B. Teehan,et al.  Continuous renal replacement therapies: an update. , 1998, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[13]  M. Illa,et al.  Autonomic nervous system and adrenergic receptors in chronic hypotensive haemodialysis patients. , 1997 .

[14]  N. Levin,et al.  Effects of body core temperature reduction on haemodynamic stability and haemodialysis efficacy at constant ultrafiltration. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[15]  G. Remuzzi,et al.  Enhanced nitric oxide synthesis in uremia: implications for platelet dysfunction and dialysis hypotension. , 1993, Kidney international.