A microwave-enhanced, solventless Mannich condensation of terminal alkynes and secondary amines with para-formaldehyde on cuprous iodide doped alumina

[1]  E. Marcantoni,et al.  Improved heteroatom nucleophilic addition to electron-poor alkenes promoted by CeCl3.7H2O/NaI system supported on alumina in solvent-free conditions. , 2005, The Journal of organic chemistry.

[2]  A. Gupta,et al.  A Facile and Scaleable Synthesis of ABT-239, A Benzofuranoid H3 Antagonist , 2005 .

[3]  C. Kappe,et al.  Controlled microwave heating in modern organic synthesis. , 2004, Angewandte Chemie.

[4]  L. Bieber,et al.  Mild and efficient synthesis of propargylamines by copper-catalyzed Mannich reaction , 2004 .

[5]  Z. Kríz,et al.  Microwave‐Assisted Elimination Reaction of trans‐4‐(4‐Fluorophenyl)‐3‐chloromethyl‐1‐methylpiperidine on Alumina , 2004 .

[6]  J. Biellmann,et al.  Synthesis of allenes via palladium-catalyzed hydrogen-transfer reactions: propargylic amines as an allenyl anion equivalent. , 2004, Journal of the American Chemical Society.

[7]  B. Arndtsen,et al.  Copper-catalyzed coupling of imines, acid chlorides, and alkynes: a multicomponent route to propargylamides. , 2004, Organic letters.

[8]  Gang Xu,et al.  Microwave-assisted amination from aryl triflates without base and catalyst. , 2004, Organic letters.

[9]  Lei Wang,et al.  Microwave Irradiated Solventless Sonogashira Reaction on Nickel(0) Powder Doped KF/Al2O3 , 2004 .

[10]  K. Luthman,et al.  Efficient large scale microwave assisted Mannich reactions using substituted acetophenones , 2004, Molecular Diversity.

[11]  Y. Kuo,et al.  Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells. , 2004, Molecular pharmacology.

[12]  M. Pal,et al.  Pd/C mediated synthesis of 2-substituted benzo[b]furans/nitrobenzo[b]furans in water☆ , 2003 .

[13]  T. Masuda,et al.  Synthesis and Properties of Amino Acid-Based Polyacetylenes , 2003 .

[14]  R. Hartley,et al.  Synthesis of 2-substituted benzofurans and indoles using functionalized titanium benzylidene reagents on solid phase. , 2003, The Journal of organic chemistry.

[15]  J. Tabei,et al.  Conformational Study of Poly(N-propargylamides) Having Bulky Pendant Groups , 2002 .

[16]  Der-Ren Hwang,et al.  A modified Mannich-type reaction catalyzed by VO(acac)(2). , 2002, Organic letters.

[17]  B. Devreese,et al.  A useful bicyclic topological decapeptide template for solution-phase combinatorial synthesis of tetrapodal libraries , 2001 .

[18]  Lei Wang,et al.  Sonogashira coupling and cyclization reactions on alumina: a route to aryl alkynes, 2-substituted-benzo[b]furans and 2-substituted-indoles , 2001 .

[19]  S. Dax,et al.  Solid-phase Mannich condensation of amines, aldehydes, and alkynes: investigation of diverse aldehyde inputs. , 2001, Journal of combinatorial chemistry.

[20]  T. Ishida,et al.  Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer. , 2001, Bioorganic & Medicinal Chemistry.

[21]  Lei Wang,et al.  Rapid microwave-enhanced, solventless Sonogashira coupling reaction on alumina , 2000 .

[22]  A. Waterson,et al.  Studies dealing with thionium ion promoted mannich cyclization reactions. , 2000, The Journal of organic chemistry.

[23]  J. Bosch,et al.  A Convergent Route to 5-(Arylsulfanyl)-6-sulfonamido-3-benzofuranones , 2000 .

[24]  Lei Wang,et al.  Microwave-assisted, solventless Suzuki coupling reactions on palladium-doped alumina , 2000 .

[25]  G. Kabalka,et al.  Solventless Suzuki Coupling Reactions on Palladium-Doped KF/Al2O3 , 1999 .

[26]  R. Larock,et al.  Palladium-Catalyzed, Asymmetric Hetero- and Carboannulation of Allenes Using Functionally-Substituted Aryl and Vinylic Iodides , 1999 .

[27]  W. König,et al.  Microwave-Assisted Aqueous Suzuki Cross-Coupling Reactions , 1999 .

[28]  K. Inouye,et al.  Total synthesis of an antioxidant isolated from yeast via palladium-catalyzed coupling and its application for related compounds. , 1999, Bioorganic & medicinal chemistry letters.

[29]  J. Percy,et al.  Facile syntheses of aryldifluorophosphonate building blocks , 1999 .

[30]  B. Trost,et al.  A Ruthenium-Catalyzed Three-Component Coupling to Form E-Vinyl Chlorides , 1999 .

[31]  P. Scammells,et al.  Synthesis of 2-Substituted 3-Acylbenzo[b]furans via the Palladium Catalysed Carbonylative Cyclisation of ortho-Hydroxytolans , 1999 .

[32]  Rajender S. Varma,et al.  Solvent-free organic syntheses. using supported reagents and microwave irradiation , 1999 .

[33]  R. Rivero,et al.  The solid phase synthesis of complex propargylamines using the combination of sonogashira and mannich reactions , 1998 .

[34]  M. Boys.  A synthesis of the platelet aggregation inhibitor xemilofiban from L-aspartic acid. Confirmation of the absolute configuration , 1998 .

[35]  S. Dax,et al.  Mannich reactions of resin-bound substrates: 2. A versatile three-component solid-phase organic synthesis methodology , 1998 .

[36]  S. Dax,et al.  MANNICH REACTIONS OF A RESIN-BOUND TERMINAL ALKYNE , 1997 .

[37]  G. Kabalka,et al.  Organic reactions on alumina , 1997 .

[38]  A. Bedeschi,et al.  Solid phase synthesis of 2-substituted benzofurans via the palladium-catalysed heteroannulation of acetylenes , 1997 .

[39]  S. Cacchi,et al.  Palladium-Catalyzed Reaction of o-Ethynylphenols, o-((Trimethylsilyl)ethynyl)phenyl Acetates, and o-Alkynylphenols with Unsaturated Triflates or Halides: A Route to 2-Substituted-, 2,3-Disubstituted-, and 2-Substituted-3-acylbenzo[b]furans , 1996 .

[40]  R. Devraj,et al.  Effect of bridge region variation on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines. , 1995, Journal of medicinal chemistry.

[41]  M. Miura,et al.  Copper-Catalyzed Reaction of Terminal Alkynes with Nitrones. Selective Synthesis of 1-Aza-1-buten-3-yne and 2-Azetidinone Derivatives , 1995 .

[42]  P. Blumberg,et al.  Effect of alteration of the heterocyclic nucleus of ILV on its isoform selectivity for PKC. Palladium catalyzed route to benzofuran analogues of ILV , 1995 .

[43]  R. Larock,et al.  Synthesis of Aromatic Heterocycles via Palladium-Catalyzed Annulation of Internal Alkynes , 1995 .

[44]  G. Kabalka,et al.  The acid-catalyzed and uncatalyzed hydrolysis of nitriles on unactivated alumina , 1995 .

[45]  L. Angiolini,et al.  Mannich Bases-Chemistry and Uses , 1994 .

[46]  R. Givens,et al.  Photochemistry of phosphate esters: .alpha.-keto phosphates as a photoprotecting group for caged phosphate , 1993 .

[47]  W. Moos,et al.  Cholinergic agents: aldehyde, ketone, and oxime analogues of the muscarinic agonist UH5 , 1992 .

[48]  R. Givens,et al.  Photochemistry of alpha-keto phosphate esters Photorelease of a caged cAMP , 1992 .

[49]  D. N. Jumbam,et al.  Titanium-induced syntheses of furans, benzofurans and indoles , 1992 .

[50]  M. Pal,et al.  Palladium-catalysed heteroannulation of acetylenic compounds : a facile method for the synthesis of benzofurans , 1992 .

[51]  R. Pedrosa,et al.  Reaction of 4-chlorocoumarin with organometallic reagents. Synthesis of trialkylbenzopyrans, 4-chlorobenzopyrans, 4-alkylcoumarins and o-hydroxyphenylprop-2-ynyl alcohols , 1992 .

[52]  G. Gribble,et al.  Reactions of Sodium Borohydride in Acidic Media; XVI.1 N-Methylation of Amines with Paraformaldehyde/Trifluoroacetic Acid , 1987 .

[53]  S. Djurić.  A mild and convenient procedure for the N-formylation of secondary amines using organosilicon chemistry , 1984 .

[54]  I. Erden.  Regio- and stereoselective cycloadditions of dichloroketene to bridged bicyclic olefins , 1984 .

[55]  H. Loibner,et al.  Reduktive methylierung primärer und sekundärer amine mit hilfe von formaldehyd und salzen der phosphorigen säure , 1984 .

[56]  K. Sonogashira,et al.  A Convenient Synthesis of Ethynylarenes and Diethynylarenes , 1980 .

[57]  C. Mannich,et al.  Über eine Synthese von organischen Basen mit dreifacher Bindung. , 1933 .