Global Virology I - Identifying and Investigating Viral Diseases

[1]  L. Hutwagner,et al.  Effective Vaccine for Lassa Fever , 2000, Journal of Virology.

[2]  N. Sardesai,et al.  Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation , 2013, Vaccines.

[3]  R. D. del Ángel,et al.  La protein binds to NS5 and NS3 and to the 5' and 3' ends of Dengue 4 virus RNA. , 2004, Virus research.

[4]  M. Eibl,et al.  Nitric oxide and viral infection: NO antiviral activity against a flavivirus in vitro, and evidence for contribution to pathogenesis in experimental infection in vivo. , 1996, Virology.

[5]  K. Stiasny,et al.  Identification of specific histidines as pH sensors in flavivirus membrane fusion , 2008, The Journal of cell biology.

[6]  S. Günther,et al.  Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro , 2004, Antiviral Research.

[7]  Xuping Xie,et al.  Membrane Topology and Function of Dengue Virus NS2A Protein , 2013, Journal of Virology.

[8]  D. A. Stein,et al.  Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. , 2006, Virology.

[9]  I. Lukashevich,et al.  Mucosal immunization with Salmonella typhimurium expressing Lassa virus nucleocapsid protein cross-protects mice from lethal challenge with lymphocytic choriomeningitis virus. , 2001, Journal of human virology.

[10]  E. Vela,et al.  Genistein treatment of cells inhibits arenavirus infection. , 2008, Antiviral research.

[11]  R. Tiwari,et al.  Japanese encephalitis: a review of the Indian perspective. , 2012, The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.

[12]  M. Weissenbacher,et al.  Protection against a pathogenic strain of Junin virus by mucosal infection with an attenuated strain. , 1983, The American journal of tropical medicine and hygiene.

[13]  A. Nisalak,et al.  Dengue in the early febrile phase: viremia and antibody responses. , 1997, The Journal of infectious diseases.

[14]  G. Karupiah,et al.  NADPH oxidase, Nramp1 and nitric oxide synthase 2 in the host antimicrobial response. , 2000, Reviews in immunogenetics.

[15]  P. Desprès,et al.  NKp44 Receptor Mediates Interaction of the Envelope Glycoproteins from the West Nile and Dengue Viruses with NK Cells1 , 2009, The Journal of Immunology.

[16]  J. Parry,et al.  An outbreak of hepatitis A: school toilets as a source of transmission. , 1992, Journal of public health medicine.

[17]  B. Gowen,et al.  Use of Recombinant Adenovirus Vectored Consensus IFN-α to Avert Severe Arenavirus Infection , 2011, PloS one.

[18]  I. Lukashevich,et al.  Arenavirus-Mediated Liver Pathology: Acute Lymphocytic Choriomeningitis Virus Infection of Rhesus Macaques Is Characterized by High-Level Interleukin-6 Expression and Hepatocyte Proliferation , 2003, Journal of Virology.

[19]  C. García,et al.  Targeting of Arenavirus RNA Synthesis by a Carboxamide-Derivatized Aromatic Disulfide with Virucidal Activity , 2013, PloS one.

[20]  K. Borden,et al.  Arenavirus Z protein as an antiviral target: virus inactivation and protein oligomerization by zinc finger-reactive compounds. , 2006, The Journal of general virology.

[21]  D. Smee,et al.  Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever , 2011, PLoS neglected tropical diseases.

[22]  R. Prayson,et al.  The neuropathology of West Nile virus meningoencephalitis. A report of two cases and review of the literature. , 2003, American journal of clinical pathology.

[23]  C. Videla,et al.  Formalin inactivated junin virus: Immunogenicity and protection assays , 1989, Journal of medical virology.

[24]  T. Kimura,et al.  Association between the pH-dependent conformational change of West Nile flavivirus E protein and virus-mediated membrane fusion. , 1988, The Journal of general virology.

[25]  B A Askonas,et al.  Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus , 1988, The Journal of experimental medicine.

[26]  I. Lukashevich.  The search for animal models for Lassa fever vaccine development , 2013, Expert review of vaccines.

[27]  J. Julander,et al.  Experimental therapies for yellow fever. , 2013, Antiviral research.

[28]  E. Damonte,et al.  Homologous and heterologous glycoproteins induce protection against Junin virus challenge in guinea pigs. , 2000, The Journal of general virology.

[29]  R. Chanock,et al.  Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys , 1996, Journal of virology.

[30]  W. Parker,et al.  Metabolism and antiviral activity of ribavirin. , 2005, Virus research.

[31]  B. Mothé,et al.  Development of a New Vaccine for the Prevention of Lassa Fever , 2005, PLoS medicine.

[32]  David C. Chang,et al.  A Translation Inhibitor That Suppresses Dengue Virus In Vitro and In Vivo , 2011, Antimicrobial Agents and Chemotherapy.

[33]  A. Nisalak,et al.  Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. , 2000, The Journal of infectious diseases.

[34]  H. Ly,et al.  Identification of Virulence Determinants within the L Genomic Segment of the Pichinde Arenavirus , 2013, Journal of Virology.

[35]  Adolfo García-Sastre,et al.  Inhibition of interferon signaling by dengue virus , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Y. Teo,et al.  Genome-wide association study identifies susceptibility loci for Dengue shock syndrome at MICB and PLCE1 , 2011, Nature Genetics.

[37]  A. Davidson,et al.  Histidine 39 in the dengue virus type 2 M protein has an important role in virus assembly. , 2004, The Journal of general virology.

[38]  David Beer,et al.  Ten years of dengue drug discovery: progress and prospects. , 2013, Antiviral research.

[39]  A. Nisalak,et al.  Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. , 1991, The Journal of clinical investigation.

[40]  E. Azeredo,et al.  Inducible nitric oxide synthase (iNOS) expression in monocytes during acute Dengue Fever in patients and during in vitro infection , 2005, BMC infectious diseases.

[41]  G. Gamboa,et al.  Argentine hemorrhagic fever vaccines , 2011, Human vaccines.

[42]  P. Jahrling,et al.  Protection of guinea pigs against experimental Argentine hemorrhagic fever by purified human IgG: importance of elimination of infected cells. , 1990, Microbial pathogenesis.

[43]  M. Rolph,et al.  Protection from arthritis and myositis in a mouse model of acute chikungunya virus disease by bindarit, an inhibitor of monocyte chemotactic protein-1 synthesis. , 2011, The Journal of infectious diseases.

[44]  E. Datan,et al.  Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication* , 2011, The Journal of Biological Chemistry.

[45]  S. Kunz,et al.  Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242. , 2012, Virology.

[46]  P. Jahrling,et al.  Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus , 2002, Journal of medical virology.

[47]  E. Harris,et al.  Control of dengue virus translation and replication. , 2010, Current topics in microbiology and immunology.

[48]  J. McCormick,et al.  Inactivated Lassa virus elicits a non protective immune response in rhesus monkeys , 1992, Journal of medical virology.

[49]  G. Freeman,et al.  TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine , 2013, PLoS pathogens.

[50]  J. Sejvar.  West nile virus: an historical overview. , 2003, The Ochsner journal.

[51]  E. Damonte,et al.  Inhibition of arenavirus multiplication in vitro by phenotiazines. , 1996, Antiviral research.

[52]  D. Smith,et al.  Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2 , 2004, Archives of Virology.

[53]  P. Jahrling,et al.  Passive antibody therapy of Lassa fever in cynomolgus monkeys: importance of neutralizing antibody and Lassa virus strain , 1984, Infection and immunity.

[54]  N. Heaton,et al.  Dengue virus-induced autophagy regulates lipid metabolism. , 2010, Cell host & microbe.

[55]  G. Eddy,et al.  Protection of monkeys against Machupo virus by the passive administration of Bolivian haemorrhagic fever immunoglobulin (human origin). , 1975, Bulletin of the World Health Organization.

[56]  E. Gould,et al.  Tick-borne encephalitis. , 2003, Antiviral research.

[57]  Qinfen Zhang,et al.  CryoEM structure of the mature dengue virus at 3.5-Å resolution , 2012, Nature Structural &Molecular Biology.

[58]  M. Diamond,et al.  West Nile Virus from Infected Neurons T Cells Require Perforin to Clear + Cd8 , 2022 .

[59]  N. King,et al.  Interaction of flaviviruses with cells of the vertebrate host and decoy of the immune response , 2003, Immunology and cell biology.

[60]  D. Gubler,et al.  Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis , 2013, Nature Reviews Microbiology.

[61]  A. Rothman,et al.  Bystander Target Cell Lysis and Cytokine Production by Dengue Virus-Specific Human CD4+ Cytotoxic T-Lymphocyte Clones , 1999, Journal of Virology.

[62]  T. Dreher,et al.  Control of Translation by the 5′- and 3′-Terminal Regions of the Dengue Virus Genome , 2005, Journal of Virology.

[63]  L. Markoff,et al.  The Topology of Bulges in the Long Stem of the Flavivirus 3′ Stem-Loop Is a Major Determinant of RNA Replication Competence , 2005, Journal of Virology.

[64]  E. D. Clercq,et al.  Inactivation of S-Adenosyl-L-homocysteine Hydrolase with Novel 5′-Thioadenosine Derivatives. Antiviral Effects. , 2003 .

[65]  A. Basu,et al.  Japanese Encephalitis Virus-Infected Macrophages Induce Neuronal Death , 2011, Journal of Neuroimmune Pharmacology.

[66]  P. Sexton,et al.  A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection. , 2014, The Journal of infectious diseases.

[67]  A. Gamarnik,et al.  Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation , 2009, PLoS pathogens.

[68]  S. Vasudevan,et al.  The Interdomain Region of Dengue NS5 Protein That Binds to the Viral Helicase NS3 Contains Independently Functional Importin β1 and Importin α/β-Recognized Nuclear Localization Signals* , 2002, The Journal of Biological Chemistry.

[69]  G. Wengler,et al.  The NS 3 nonstructural protein of flaviviruses contains an RNA triphosphatase activity. , 1993, Virology.

[70]  L. Petersen,et al.  West Nile Virus: A Primer for the Clinician , 2002, Annals of Internal Medicine.

[71]  E. De Clercq,et al.  The Predominant Mechanism by Which Ribavirin Exerts Its Antiviral Activity In Vitro against Flaviviruses and Paramyxoviruses Is Mediated by Inhibition of IMP Dehydrogenase , 2005, Journal of Virology.

[72]  P. G. Canonico.  Efficacy, toxicology and clinical applications of ribavirin against virulent RNA viral infections. , 1985, Antiviral research.

[73]  E. Harris,et al.  Poly(A)-binding protein binds to the non-polyadenylated 3' untranslated region of dengue virus and modulates translation efficiency. , 2009, The Journal of general virology.

[74]  A. Gamarnik,et al.  A balance between circular and linear forms of the dengue virus genome is crucial for viral replication. , 2010, RNA.

[75]  T. Pierson,et al.  Protonation of Individual Histidine Residues Is Not Required for the pH-Dependent Entry of West Nile Virus: Evaluation of the “Histidine Switch” Hypothesis , 2009, Journal of Virology.

[76]  T. Cosgriff,et al.  Hematological and bone marrow effects of ribavirin in rhesus monkeys. , 1984, Toxicology and applied pharmacology.

[77]  M. Kielian,et al.  In Vitro and In Vivo Studies Identify Important Features of Dengue Virus pr-E Protein Interactions , 2010, PLoS pathogens.

[78]  E. Damonte,et al.  Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis. , 2008, The Journal of general virology.

[79]  K. Murthy,et al.  Modulation of the Nucleoside Triphosphatase/RNA Helicase and 5′-RNA Triphosphatase Activities of Dengue Virus Type 2 Nonstructural Protein 3 (NS3) by Interaction with NS5, the RNA-dependent RNA Polymerase* , 2005, Journal of Biological Chemistry.

[80]  J. Smit,et al.  Immature Dengue Virus: A Veiled Pathogen? , 2010, PLoS pathogens.

[81]  S. Kunz,et al.  Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers. , 2008, Virology.

[82]  Steffen Jung,et al.  Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.

[83]  Z. Brumme,et al.  HIV-1 Mutational Escape from Host Immunity , 2014 .

[84]  P. Jahrling,et al.  EXPERIMENTAL LASSA FEVER VIRUS INFECTION SUCCESSFULLY TREATED WITH RIBAVIRIN , 1979, The Lancet.

[85]  L. Chernomordik,et al.  Dengue Virus Ensures Its Fusion in Late Endosomes Using Compartment-Specific Lipids , 2010, PLoS pathogens.

[86]  V. Nerurkar,et al.  Reversal of West Nile virus-induced blood-brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor. , 2010, Virology.

[87]  B. Gowen,et al.  Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever , 2013, PLoS neglected tropical diseases.

[88]  M. Kende,et al.  In-vivo activity of antivirals against exotic RNA viral infections. , 1984, The Journal of antimicrobial chemotherapy.

[89]  G. Lloyd,et al.  VACCINIA RECOMBINANT EXPRESSING LASSA-VIRUS INTERNAL NUCLEOCAPSID PROTEIN PROTECTS GUINEAPIGS AGAINST LASSA FEVER , 1987, The Lancet.

[90]  Xiaoqun Duan,et al.  Novel binding between pre-membrane protein and claudin-1 is required for efficient dengue virus entry. , 2010, Biochemical and biophysical research communications.

[91]  C. Peters,et al.  Effect of ribavirin and tributylribavirin on argentine hemorrhagic fever (Junin virus) in guinea pigs , 1986, Antimicrobial Agents and Chemotherapy.

[92]  E. De Clercq,et al.  Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design. , 1992, Journal of medicinal chemistry.

[93]  J. Chu,et al.  Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus , 2010, Virology Journal.

[94]  T. Ksiazek,et al.  Treatment of Bolivian hemorrhagic fever with intravenous ribavirin. , 1997, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[95]  H. Doerr,et al.  Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells. , 2007, The Journal of antimicrobial chemotherapy.

[96]  K. Johnson,et al.  PROTECTION OF RHESUS MONKEYS FROM LASSA VIRUS BY IMMUNISATION WITH CLOSELY RELATED ARENAVIRUS , 1979, The Lancet.

[97]  L. Lanier,et al.  NKG2D Receptor Signaling Enhances Cytolytic Activity by Virus-Specific CD8+ T Cells: Evidence for a Protective Role in Virus-Induced Encephalitis , 2007, Journal of Virology.

[98]  S. Nichol,et al.  Reverse Genetics Generation of Chimeric Infectious Junin/Lassa Virus Is Dependent on Interaction of Homologous Glycoprotein Stable Signal Peptide and G2 Cytoplasmic Domains , 2010, Journal of Virology.

[99]  Cathy H. Wu,et al.  Sequence signatures in envelope protein may determine whether flaviviruses produce hemorrhagic or encephalitic syndromes , 2009, Virus Genes.

[100]  N. Heaton,et al.  Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis , 2010, Proceedings of the National Academy of Sciences.

[101]  J. McCormick,et al.  Construction of a recombinant vaccinia virus expressing the Lassa virus glycoprotein gene and protection of guinea pigs from a lethal Lassa virus infection. , 1988, Virus research.

[102]  J. Fu,et al.  Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. , 1998, Virology.

[103]  A. Fernández-Sesma,et al.  Inhibition of the Type I Interferon Response in Human Dendritic Cells by Dengue Virus Infection Requires a Catalytically Active NS2B3 Complex , 2010, Journal of Virology.

[104]  R. Jarman,et al.  A Prospective Nested Case-Control Study of Dengue in Infants: Rethinking and Refining the Antibody-Dependent Enhancement Dengue Hemorrhagic Fever Model , 2009, PLoS medicine.

[105]  Xiaoqun Duan,et al.  Novel binding between pre-membrane protein and vacuolar ATPase is required for efficient dengue virus secretion. , 2008, Biochemical and biophysical research communications.

[106]  S. M. Amberg,et al.  pH-Induced Activation of Arenavirus Membrane Fusion Is Antagonized by Small-Molecule Inhibitors , 2008, Journal of Virology.

[107]  F. J. Geske,et al.  Lassa virus-like particles displaying all major immunological determinants as a vaccine candidate for Lassa hemorrhagic fever , 2010, Virology Journal.

[108]  V. Romanowski,et al.  Molecular characterization of attenuated Junin virus strains. , 1997, The Journal of general virology.

[109]  K. Mayer,et al.  Antiretroviral therapy as HIV prevention: status and prospects. , 2010, American journal of public health.

[110]  A. Kwong,et al.  Broad-Spectrum Antiviral Activity of the IMP Dehydrogenase Inhibitor VX-497: a Comparison with Ribavirin and Demonstration of Antiviral Additivity with Alpha Interferon , 2000, Antimicrobial Agents and Chemotherapy.

[111]  O. Schwartz,et al.  The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. , 2012, Cell host & microbe.

[112]  E. Harris,et al.  Dengue Virus Utilizes a Novel Strategy for Translation Initiation When Cap-Dependent Translation Is Inhibited , 2006, Journal of Virology.

[113]  T. Cosgriff,et al.  Morphological alterations in blood and bone marrow of ribavirin-treated monkeys. , 1984, Acta haematologica.

[114]  A. Gamarnik,et al.  Uncoupling cis-Acting RNA Elements from Coding Sequences Revealed a Requirement of the N-Terminal Region of Dengue Virus Capsid Protein in Virus Particle Formation , 2011, Journal of Virology.

[115]  M. Ramachandra,et al.  Association between NS3 and NS5 Proteins of Dengue Virus Type 2 in the Putative RNA Replicase Is Linked to Differential Phosphorylation of NS5 (*) , 1995, The Journal of Biological Chemistry.

[116]  J. Mackenzie,et al.  Antibody-dependent enhancement of Murray Valley encephalitis virus virulence in mice. , 2003, The Journal of general virology.

[117]  Ying Zhang,et al.  Structures of immature flavivirus particles , 2003, The EMBO journal.

[118]  J. R. Brown,et al.  Effects of ribavirin on red blood cells. , 1984, Toxicology and applied pharmacology.

[119]  P. Horby,et al.  Atlas of human infectious diseases. , 2012 .

[120]  S. Kunz,et al.  Antiviral Activity of a Small-Molecule Inhibitor of Arenavirus Glycoprotein Processing by the Cellular Site 1 Protease , 2010, Journal of Virology.

[121]  K E Ebner,et al.  Cotranslational Membrane Insertion of the Serine Proteinase Precursor NS2B-NS3(Pro) of Dengue Virus Type 2 Is Required for Efficient in Vitro Processing and Is Mediated through the Hydrophobic Regions of NS2B* , 1997, The Journal of Biological Chemistry.

[122]  C. Schmaljohn,et al.  Progress in recombinant DNA-derived vaccines for Lassa virus and filoviruses. , 2011, Virus research.

[123]  J. McCormick,et al.  Effect of Ribavirin and immune serum on Junin virus-infected primates , 2005, Medical Microbiology and Immunology.

[124]  D. Boger,et al.  Unique Small Molecule Entry Inhibitors of Hemorrhagic Fever Arenaviruses* , 2008, Journal of Biological Chemistry.

[125]  R. Doms,et al.  Castanospermine, a Potent Inhibitor of Dengue Virus Infection In Vitro and In Vivo , 2005, Journal of Virology.

[126]  P. Jahrling,et al.  Antiviral efficacy of pyrazofurin against selected RNA viruses. , 1982, Antiviral research.

[127]  Eduardo Massad,et al.  DengueTools: innovative tools and strategies for the surveillance and control of dengue , 2012, Global health action.

[128]  A. Mantovani,et al.  Impact of the anti-inflammatory agent bindarit on the chemokinome: selective inhibition of the monocyte chemotactic proteins. , 2008, European cytokine network.

[129]  P. Kissinger,et al.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. , 1998, The New England journal of medicine.

[130]  P. Schlagenhauf,et al.  Infectious diseases: a geographic guide , 2017 .

[131]  P. Yenchitsomanus,et al.  Interaction of dengue virus envelope protein with endoplasmic reticulum-resident chaperones facilitates dengue virus production. , 2009, Biochemical and biophysical research communications.

[132]  M. Katze,et al.  A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes , 2013, PLoS pathogens.

[133]  S. Halstead,et al.  Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection , 2013, Archives of Virology.

[134]  H. Budka,et al.  Inflammatory response in human tick-borne encephalitis: analysis of postmortem brain tissue , 2006, Journal of NeuroVirology.

[135]  I. Lukashevich.  Generation of reassortants between African arenaviruses. , 1992, Virology.

[136]  D. A. Stein,et al.  Inhibition of Flavivirus Infections by Antisense Oligomers Specifically Suppressing Viral Translation and RNA Replication , 2005, Journal of Virology.

[137]  M. Weissenbacher,et al.  Nasal and intrathalamic inoculations of primates with Tacaribe virus: protection against Argentine hemorrhagic fever and absence of neurovirulence. , 1984, Acta virologica.

[138]  J. Pachter,et al.  The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis , 2012, Journal of Neuroinflammation.

[139]  F. Cox.  Historical Overview of Global Infectious Diseases and Geopolitics , 2011 .

[140]  M. Teixeira,et al.  A Model of DENV-3 Infection That Recapitulates Severe Disease and Highlights the Importance of IFN-γ in Host Resistance to Infection , 2012, PLoS neglected tropical diseases.

[141]  P. Yenchitsomanus,et al.  Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis. , 2010, Virus research.

[142]  J. Gonzalez,et al.  Review of Climate, Landscape, and Viral Genetics as Drivers of the Japanese Encephalitis Virus Ecology , 2013, PLoS neglected tropical diseases.

[143]  Wei Zhang,et al.  Structure of Dengue Virus Implications for Flavivirus Organization, Maturation, and Fusion , 2002, Cell.

[144]  M. Buchmeier,et al.  Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding Lassa virus nucleoprotein. , 2005, Virology.

[145]  P. Jahrling,et al.  Endemic Lassa fever in Liberia. IV. Selection of optimally effective plasma for treatment by passive immunization. , 1985, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[146]  E. Fikrig,et al.  prM-antibody renders immature West Nile virus infectious in vivo. , 2011, The Journal of general virology.

[147]  J. Connolly,et al.  Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model. , 2011, Antiviral research.

[148]  R. Hall,et al.  Efficient trans-Complementation of the Flavivirus Kunjin NS5 Protein but Not of the NS1 Protein Requires Its Coexpression with Other Components of the Viral Replicase , 1999, Journal of Virology.

[149]  E. De Clercq,et al.  Molecular approaches for the treatment of hemorrhagic fever virus infections. , 1993, Antiviral research.

[150]  Carol Beth Post,et al.  Solution structure of dengue virus capsid protein reveals another fold. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[151]  Charles M. Rice,et al.  Flaviviridae :T he Viruses and Their Replication , 2007 .

[152]  D. Jans,et al.  CRM1-mediated Nuclear Export of Dengue Virus RNA Polymerase NS5 Modulates Interleukin-8 Induction and Virus Production* , 2009, The Journal of Biological Chemistry.

[153]  A. Gamarnik,et al.  A 5' RNA element promotes dengue virus RNA synthesis on a circular genome. , 2006, Genes & development.

[154]  A. Basu,et al.  Japanese Encephalitis—A Pathological and Clinical Perspective , 2009, PLoS neglected tropical diseases.

[155]  A. Ullrich,et al.  The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells , 2014, Nature.

[156]  M. Rossmann,et al.  Association of the pr Peptides with Dengue Virus at Acidic pH Blocks Membrane Fusion , 2009, Journal of Virology.

[157]  I. Lukashevich,et al.  A Live Attenuated Vaccine for Lassa Fever Made by Reassortment of Lassa and Mopeia Viruses , 2005, Journal of Virology.

[158]  A. Suhrbier,et al.  Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins. , 2009, Arthritis and rheumatism.

[159]  S. Harrison,et al.  Small-Molecule Inhibitors of Dengue-Virus Entry , 2012, PLoS pathogens.

[160]  E. Harris,et al.  Enhancement of dengue virus translation: role of the 3' untranslated region and the terminal 3' stem-loop domain. , 2004, Virology.

[161]  Ralf Bartenschlager,et al.  Architecture and biogenesis of plus-strand RNA virus replication factories. , 2013, World journal of virology.

[162]  Paolo Sassone-Corsi,et al.  Bindarit: an anti-inflammatory small molecule that modulates the NFκB pathway. , 2012, Cell cycle.

[163]  M. Ng,et al.  Human Sec3 protein is a novel transcriptional and translational repressor of flavivirus , 2010, Cellular microbiology.

[164]  D. A. Stein,et al.  Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer , 2010, The Journal of antimicrobial chemotherapy.

[165]  N. King,et al.  Molecules in focus: indoleamine 2,3-dioxygenase. , 2007, The international journal of biochemistry & cell biology.

[166]  C. Sariol,et al.  Dengue Virus Subverts the Interferon Induction Pathway via NS2B/3 Protease-IκB Kinase ε Interaction , 2013, Clinical and Vaccine Immunology.

[167]  J. Mackenzie,et al.  Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein , 2006, Journal of Virology.

[168]  A. Gamarnik,et al.  Dynamic RNA structures in the dengue virus genome , 2011, RNA biology.

[169]  D. Kioussis,et al.  Contribution of  Virus-specific CD8+ Cytotoxic T Cells to Virus Clearance or Pathologic Manifestations of Influenza Virus Infection in a T Cell Receptor Transgenic Mouse Model , 1998, The Journal of experimental medicine.

[170]  C. García,et al.  Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever. , 2011, Antiviral research.

[171]  C. Coto,et al.  Cross-protection between Tacaribe complex viruses. Presence of neutralizing antibodies against Junin virus (Argentine hemorrhagic fever) in guinea pigs infected with Tacaribe virus. , 1975, Intervirology.

[172]  M. Diamond,et al.  Identification of Novel Small-Molecule Inhibitors of West Nile Virus Infection , 2007, Journal of Virology.

[173]  John S. Brownstein,et al.  The global distribution and burden of dengue , 2013, Nature.

[174]  L. Xia,et al.  Murine immune responses to mucosally delivered Salmonella expressing Lassa fever virus nucleoprotein. , 2000, Vaccine.

[175]  P. Jahrling,et al.  Individual and Bivalent Vaccines Based on Alphavirus Replicons Protect Guinea Pigs against Infection with Lassa and Ebola Viruses , 2001, Journal of Virology.

[176]  J. Ramirez,et al.  Antiviral Effect of Brassinosteroids against Herpes Virus and Arenaviruses , 2000, Antiviral chemistry & chemotherapy.

[177]  C. Peters,et al.  Treatment of Junin Virus‐Infected Guinea Pigs With Immune Serum: Development of Late Neurological Disease , 1986, Journal of Medical Virology.

[178]  R. D. Allen,et al.  Evaluation of Lassa antiviral compound ST-193 in a guinea pig model , 2011, Antiviral Research.

[179]  C. Rice,et al.  Genetic Interaction of Flavivirus Nonstructural Proteins NS1 and NS4A as a Determinant of Replicase Function , 1999, Journal of Virology.

[180]  E. Damonte,et al.  Imidazo[2,1-b]thiazole carbohydrate derivatives: Synthesis and antiviral activity against Junin virus, agent of Argentine hemorrhagic fever. , 2011, European journal of medicinal chemistry.

[181]  Ralf Bartenschlager,et al.  Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites , 2009, Cell Host & Microbe.

[182]  Y. Modis,et al.  Viral Membrane Fusion and Nucleocapsid Delivery into the Cytoplasm are Distinct Events in Some Flaviviruses , 2013, PLoS pathogens.

[183]  A. Gamarnik,et al.  Essential Role of Dengue Virus Envelope Protein N Glycosylation at Asparagine-67 during Viral Propagation , 2007, Journal of Virology.

[184]  H. Feldmann,et al.  Properties of Replication-Competent Vesicular Stomatitis Virus Vectors Expressing Glycoproteins of Filoviruses and Arenaviruses , 2004, Journal of Virology.

[185]  E. Kroon,et al.  Intracerebral infection with dengue-3 virus induces meningoencephalitis and behavioral changes that precede lethality in mice , 2011, Journal of Neuroinflammation.

[186]  D. Smee,et al.  T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture , 2010, Antimicrobial Agents and Chemotherapy.

[187]  Ying Zhang,et al.  The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation , 2008, Science.

[188]  E. Gould,et al.  CD8+ T-cells mediate immunopathology in tick-borne encephalitis. , 2009, Virology.

[189]  C. Lai,et al.  Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease , 1992, Journal of virology.

[190]  N. Van Rooijen,et al.  Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response1 , 2004, The Journal of Immunology.

[191]  A. Sampath,et al.  Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. , 2006, The Journal of general virology.

[192]  A. Pletnev,et al.  Growth-restricted dengue virus mutants containing deletions in the 5' noncoding region of the RNA genome. , 1995, Virology.

[193]  W. Almirón,et al.  Comparison of Argentinean Saint Louis Encephalitis Virus Non-Epidemic and Epidemic Strain Infections in an Avian Model , 2011, PLoS neglected tropical diseases.

[194]  S. Aguirre,et al.  DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING , 2012, PLoS pathogens.

[195]  B. Falgout,et al.  A conserved internal hydrophobic domain mediates the stable membrane integration of the dengue virus capsid protein. , 1997, Virology.

[196]  J Leibowitch,et al.  Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS). , 1983, Science.

[197]  C. Peters,et al.  Actions of complement on Junin virus. , 1989, Reviews of infectious diseases.

[198]  Bimmi Shrestha,et al.  Immune modulation by flaviviruses. , 2003, Advances in virus research.

[199]  D. Smee,et al.  Treatment of Late Stage Disease in a Model of Arenaviral Hemorrhagic Fever: T-705 Efficacy and Reduced Toxicity Suggests an Alternative to Ribavirin , 2008, PloS one.

[200]  N. King,et al.  Regulation of immune recognition molecules by flavivirus, West Nile. , 2002, Viral immunology.

[201]  R. Bartenschlager,et al.  Exploitation of cellular pathways by Dengue virus. , 2011, Current opinion in microbiology.

[202]  D. Smee,et al.  Interferon Alfacon-1 Protects Hamsters from Lethal Pichinde Virus Infection , 2005, Antimicrobial Agents and Chemotherapy.

[203]  P. Iversen,et al.  Lymphocytic Choriomeningitis Virus Infection in FVB Mouse Produces Hemorrhagic Disease , 2012, PLoS pathogens.

[204]  T. Pierson,et al.  A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus , 2011, PLoS pathogens.

[205]  A. Kolokoltsov,et al.  Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin , 2011, Archives of Virology.

[206]  P. Jahrling.  Protection of lassa virus‐infected guinea pigs with lassa‐immune plasma of guinea pig, primate, and human origin , 1983, Journal of medical virology.

[207]  J. Clements,et al.  Neuroprotective and anti-human immunodeficiency virus activity of minocycline. , 2005, JAMA.

[208]  S. Saxena,et al.  Antiviral effect of nitric oxide during Japanese encephalitis virus infection. , 2000, International journal of experimental pathology.

[209]  P. Jahrling,et al.  Enhanced treatment of Lassa fever by immune plasma combined with ribavirin in cynomolgus monkeys. , 1984, The Journal of infectious diseases.

[210]  H. Agaisse,et al.  Rab 5 Is Required for the Cellular Entry of Dengue and West Nile Viruses , 2007, Journal of Virology.

[211]  B. McColl,et al.  Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms , 2007, The Journal of Neuroscience.

[212]  B. Gowen,et al.  Vascular leak ensues a vigorous proinflammatory cytokine response to Tacaribe arenavirus infection in AG129 mice , 2013, Virology Journal.

[213]  T. E. Ryan,et al.  Identification and characterization of type 2 dengue virus replicative intermediate and replicative form RNAs. , 1981, Virology.

[214]  C. Cameron,et al.  The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase , 2001, Current opinion in infectious diseases.

[215]  I. Lukashevich,et al.  Yellow fever 17D-vectored vaccines expressing Lassa virus GP1 and GP2 glycoproteins provide protection against fatal disease in guinea pigs. , 2011, Vaccine.

[216]  M. Kozak.  Structural features in eukaryotic mRNAs that modulate the initiation of translation. , 1991, The Journal of biological chemistry.

[217]  A. Aggarwal,et al.  An epidemic of dengue hemorrhagic fever and dengue shock syndrome in children in Delhi. , 1998, Indian pediatrics.

[218]  E. Kroon,et al.  Nitric oxide synthase expression correlates with death in an experimental mouse model of dengue with CNS involvement , 2013, Virology Journal.

[219]  Horacio Zamudio-Meza,et al.  Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells. , 2009, The Journal of general virology.

[220]  B. Rouse,et al.  CD4+CD25+ Regulatory T Cells Control the Severity of Viral Immunoinflammatory Lesions1 , 2004, The Journal of Immunology.

[221]  Eva Harris,et al.  RNA Secondary Structure in the Coding Region of Dengue Virus Type 2 Directs Translation Start Codon Selection and Is Required for Viral Replication , 2006, Journal of Virology.

[222]  M. Mendenhall,et al.  In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections , 2007, Antimicrobial Agents and Chemotherapy.

[223]  Wei Chen,et al.  Roles of Small GTPase Rac1 in the Regulation of Actin Cytoskeleton during Dengue Virus Infection , 2010, PLoS neglected tropical diseases.

[224]  M. Diamond,et al.  CD4+ T-Cell Responses Are Required for Clearance of West Nile Virus from the Central Nervous System , 2006, Journal of Virology.

[225]  J. Kuhn,et al.  Machupo Virus Glycoprotein Determinants for Human Transferrin Receptor 1 Binding and Cell Entry , 2011, PloS one.

[226]  M. Oldstone,et al.  Pathogenesis of Lassa fever virus infection: I. Susceptibility of mice to recombinant Lassa Gp/LCMV chimeric virus. , 2013, Virology.

[227]  Wei Zhang,et al.  Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation , 2008, Science.

[228]  S. Günther,et al.  Inhibition of Different Lassa Virus Strains by Alpha and Gamma Interferons and Comparison with a Less Pathogenic Arenavirus , 2004, Journal of Virology.

[229]  R. D. del Ángel,et al.  Heat Shock Protein 90 and Heat Shock Protein 70 Are Components of Dengue Virus Receptor Complex in Human Cells , 2005, Journal of Virology.

[230]  T. Pierson,et al.  Nucleolin Interacts with the Dengue Virus Capsid Protein and Plays a Role in Formation of Infectious Virus Particles , 2013, Journal of Virology.

[231]  D. A. Stein,et al.  Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus , 2008, The Journal of antimicrobial chemotherapy.

[232]  G. Áñez,et al.  Short report: increased level of serum nitric oxide in patients with dengue. , 2002, The American journal of tropical medicine and hygiene.

[233]  F. Tangy,et al.  Vaccines in Development against West Nile Virus , 2013, Viruses.

[234]  Ralf Bartenschlager,et al.  The Non-structural Protein 4A of Dengue Virus Is an Integral Membrane Protein Inducing Membrane Alterations in a 2K-regulated Manner* , 2007, Journal of Biological Chemistry.

[235]  N. King,et al.  Transcriptional regulation of major histocompatibility complex class I by flavivirus West Nile is dependent on NF-kappaB activation. , 2001, The Journal of infectious diseases.

[236]  J. Farrar,et al.  Genetic Variants of MICB and PLCE1 and Associations with Non-Severe Dengue , 2013, PloS one.

[237]  Michael J Rust,et al.  Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living Cells , 2008, PLoS pathogens.

[238]  H. Lortat-Jacob,et al.  Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus. , 2002, Virology.

[239]  A. Gamarnik,et al.  Functional RNA Elements in the Dengue Virus Genome , 2011, Viruses.

[240]  Valorie D. Bowman,et al.  Influence of pr-M Cleavage on the Heterogeneity of Extracellular Dengue Virus Particles , 2010, Journal of Virology.

[241]  E. A. Christian,et al.  Atomic-level functional model of dengue virus Envelope protein infectivity , 2013, Proceedings of the National Academy of Sciences.

[242]  R. Dwek,et al.  The Mannose Receptor Mediates Dengue Virus Infection of Macrophages , 2008, PLoS pathogens.

[243]  Evan Wood,et al.  Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study , 2010, The Lancet.

[244]  C. Thepparit,et al.  Serotype-Specific Entry of Dengue Virus into Liver Cells: Identification of the 37-Kilodalton/67-Kilodalton High-Affinity Laminin Receptor as a Dengue Virus Serotype 1 Receptor , 2004, Journal of Virology.

[245]  J. McCormick,et al.  Therapeutic Effect of the Antiviral Agent Ribavirin in Junin Virus Infection of Primates , 1986, Journal of medical virology.

[246]  Ying Zhang,et al.  Visualization of membrane protein domains by cryo-electron microscopy of dengue virus , 2003, Nature Structural Biology.

[247]  Yee‐Shin Lin,et al.  Heparin inhibits dengue-2 virus infection of five human liver cell lines. , 2002, Antiviral research.

[248]  R. D. del Ángel,et al.  Identification of a Putative Coreceptor on Vero Cells That Participates in Dengue 4 Virus Infection , 2001, Journal of Virology.

[249]  R. Steinman,et al.  DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells , 2003, The Journal of experimental medicine.

[250]  H. Ly,et al.  Characterization of virulence-associated determinants in the envelope glycoprotein of Pichinde virus. , 2012, Virology.

[251]  C. Lai,et al.  Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins , 1991, Journal of virology.

[252]  P. Jahrling,et al.  Pathogenesis of a Pichinde Virus Strain Adapted to Produce Lethal Infections in Guinea Pigs , 1981, Infection and immunity.

[253]  J. Aaskov,et al.  Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection. , 2008, The Journal of general virology.

[254]  Rachel E. Owen,et al.  Tregs control the development of symptomatic West Nile virus infection in humans and mice. , 2009, The Journal of clinical investigation.

[255]  G. Chinea,et al.  Characterization of the interaction of domain III of the envelope protein of dengue virus with putative receptors from CHO cells. , 2008, Virus research.

[256]  J. McCormick,et al.  Lassa fever. Effective therapy with ribavirin. , 1986, The New England journal of medicine.

[257]  P. Desprès,et al.  Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN)-mediated Enhancement of Dengue Virus Infection Is Independent of DC-SIGN Internalization Signals* , 2005, Journal of Biological Chemistry.

[258]  J. Kaur,et al.  Insights into the Internalization and Retrograde Trafficking of Dengue 2 Virus in BHK-21 Cells , 2011, PloS one.

[259]  D. Bausch,et al.  Ribavirin for Lassa Fever Postexposure Prophylaxis , 2010, Emerging infectious diseases.

[260]  S. Saxena,et al.  Induction of nitric oxide synthase during Japanese encephalitis virus infection: evidence of protective role. , 2001, Archives of biochemistry and biophysics.

[261]  S. Cordo,et al.  Myristic acid analogs are inhibitors of Junin virus replication. , 1999, Microbes and infection.