In-Vivo Measurements; Pitfalls and Problems of Instrumentation

This chapter is not designed to provide detailed information about how to make physiological measurements. In some cases references are provided which will supply that kind of information. The purpose of this chapter is to point out some of the problems and pitfalls involved in physiological measurements. Judging by how many of these problems are apparently ignored it seems that many investigators are unaware of them.

[1]  D. R. Gross,et al.  Hot‐Film Anemometer Velocity Measurements of Arterial Blood Flow in Horses , 1974, Circulation research.

[2]  F. Grodins,et al.  Basic Concepts in the Determination of vascular Volumes by Indicator‐Dilution Methods , 1962, Circulation research.

[3]  G. Stewart,et al.  Researches on the Circulation Time and on the Influences which affect it , 1897, The Journal of physiology.

[4]  G. Stewart,et al.  THE PULMONARY CIRCULATION TIME, THE QUANTITY OF BLOOD IN THE LUNGS AND THE OUTPUT OF THE HEART , 1921 .

[5]  A. Guyton,et al.  Interstitial Fluid Pressure: II. Pressure‐Volume Curves of Interstitial Space , 1965, Circulation research.

[6]  R. F. Rushmer,et al.  Left Ventricular Dimensions Recorded by Sonocardiometry , 1956, Circulation research.

[7]  H. Suga,et al.  Instantaneous Pressure‐Volume Relationships and Their Ratio in the Excised, Supported Canine Left Ventricle , 1974, Circulation research.

[8]  J. Peterson,et al.  Transmural pH gradient in canine myocardial ischemia. , 1984, The American journal of physiology.

[9]  S R Goldstein,et al.  A miniature fiber optic pH sensor for physiological use. , 1980, Journal of biomechanical engineering.

[10]  M. Noble,et al.  Total and Regional Coronary Blood Flow Measured by Radioactive Microspheres in Conscious and Anesthetized Dogs , 1969, Circulation research.

[11]  J. S. Rankin,et al.  Dynamic Ventricular Interaction in the Conscious Dog , 1983, Circulation research.

[12]  A. Guyton,et al.  Interstitial Fluid Pressure , 1966, Circulation research.

[13]  B. Surawicz,et al.  Comparison of cardiac monophasic action potentials recorded by intracellular and suction electrodes. , 1959, The American journal of physiology.

[14]  W. F. Hamilton,et al.  STUDIES ON THE CIRCULATION: I. Injection Method: Physical and Mathematical Considerations , 1929 .

[15]  T. G. Coleman,et al.  Hemodynamic disturbances in the rat as a function of the number of microspheres injected. , 1983, The American journal of physiology.

[16]  R. Jennings,et al.  The Changing Anatomic Reference Base of Evolving Myocardial Infarction: Underestimation of Myocardial Collateral Blood Flow and Overestimation of Experimental Anatomic Infarct Size Due to Tissue Edema, Hemorrhage and Acute Inflammation , 1979, Circulation.

[17]  F. Cobb,et al.  Effects of Infarcted Myocardium on Regional Blood Flow Measurements to Ischemic Regions in Canine Heart , 1980, Circulation research.

[18]  E. Landis.  CAPILLARY PRESSURE AND CAPILLARY PERMEABILITY , 1934 .

[19]  K. Scheel,et al.  Interstitial Fluid Pressure: III. Its Effect on Resistance to Tissue Fluid Mobility , 1966 .

[20]  Helmut Hinghofer-Szalkay,et al.  Cardiovascular system dynamics : models and measurements , 1982 .

[21]  H. L. Stone,et al.  A portable, simple sonomicrometer. , 1967, Journal of applied physiology.

[22]  W. F. Hamilton,et al.  STUDIES ON THE CIRCULATION , 1932 .

[23]  R. Reed,et al.  Interstitial fluid pressure in rats measured with a modified wick technique. , 1977, Microvascular research.

[24]  S. Epstein,et al.  Loss of Microspheres from Ischemic Canine Cardiac Tissue , 1979, Circulation research.

[25]  P. F. Scholander,et al.  Negative pressure in the interstitial fluid of animals. Fluid tensions are spectacular in plants; in animals they are elusively small, but just as vital. , 1968, Science.

[26]  L. Becker,et al.  The Loss of Radioactive Microspheres from Canine Necrotic Myocardium , 1979, Circulation research.

[27]  A C Guyton,et al.  Interstitial Fluid Pressure , 1968, Circulation research.

[28]  J. S. Cole,et al.  An ultrasonic pulsed Doppler system for measuring blood flow in small vessels. , 1974, Journal of applied physiology.

[29]  M. Lab,et al.  Monophasic action potentials, electrocardiograms and mechanical performance in normal and ischaemic epicardial segments of the pig ventricle in situ. , 1978, Cardiovascular research.

[30]  L. Churney,et al.  AN IMPROVED SUCTION ELECTRODE FOR RECORDING FROM THE DOG HEART IN SITU. , 1964, Journal of applied physiology.

[31]  M R Franz,et al.  Long-term recording of monophasic action potentials from human endocardium. , 1983, The American journal of cardiology.

[32]  L. Sapirstein,et al.  Regional blood flow by fractional distribution of indicators. , 1958, The American journal of physiology.

[33]  D. Wieting,et al.  Turbulent flow through a natural human mitral valve. , 1977, Journal of biomechanics.