Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia
暂无分享,去创建一个
Gen Li | Jian Pan | F. Fang | Shaoyan Hu | Zhiheng Li | Xuan Sang | J. Ling | Yanfang Tao | Jun Lu | Chenxi Feng | Yanling Chen | Xinran Chu | Zi-Mu Zhang | Xiao-lu Li | Juanjuan Yu | Yuanshi Tian | Yi Xie | Di Wu | Yong-ping Zhang | Jianwei Wang | Siqi Jia | Shuilian Wu | Chen-xi Feng | Si-Qi Jia | X. Sang | Xiao-Lu Li | Zimu Zhang | Fang Fang
[1] M. Fullwood,et al. Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma , 2021, Cancer Research.
[2] Lin Chen,et al. Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers , 2021, Nature Communications.
[3] Weilong Hong,et al. Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway , 2021, Molecular Therapy. Nucleic Acids.
[4] Haitao Wang,et al. Key sunitinib‐related biomarkers for renal cell carcinoma , 2021, Cancer medicine.
[5] Cheng Huang,et al. Super-enhancer-associated TMEM44-AS1 aggravated glioma progression by forming a positive feedback loop with Myc , 2021, Journal of experimental & clinical cancer research : CR.
[6] Cun-Yu Wang,et al. Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma , 2021, Nature Communications.
[7] S. Kesari,et al. Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling , 2021, BMC Neurology.
[8] F. Zanini,et al. Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells. , 2021, Blood.
[9] Catherine Lai,et al. Advances in therapeutic options for newly diagnosed, high-risk AML patients , 2021, Therapeutic advances in hematology.
[10] W. Wang,et al. Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling , 2021, Nature Communications.
[11] C. Récher. Clinical Implications of Inflammation in Acute Myeloid Leukemia , 2021, Frontiers in Oncology.
[12] Blandine Roux,et al. Descriptive and Functional Genomics in Acute Myeloid Leukemia (AML): Paving the Road for a Cure , 2021, Cancers.
[13] K. Ozato,et al. DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner , 2020, Frontiers in Molecular Biosciences.
[14] B. Göttgens,et al. Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells , 2020, bioRxiv.
[15] Liewei Wang,et al. Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer , 2020, Oncogene.
[16] Iris Z. Uras,et al. CDK6 Inhibition: A Novel Approach in AML Management , 2020, International journal of molecular sciences.
[17] D. Hao,et al. Overexpression of FES might inhibit cell proliferation, migration, and invasion of osteosarcoma cells , 2020, Cancer Cell International.
[18] I. Touw,et al. RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia , 2020, Molecules and cells.
[19] D. Beck,et al. Shared roles for Scl and Lyl1 in murine platelet production and function. , 2019, Blood.
[20] B. Ko,et al. Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome , 2019, BMC Cancer.
[21] Trevor Siggers,et al. NextPBM: a platform to study cell-specific transcription factor binding and cooperativity , 2019, Nucleic acids research.
[22] C. Wells,et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias , 2018, Nature Communications.
[23] Yizhou Huang,et al. A novel role for Lyl1 in primitive erythropoiesis , 2018, Development.
[24] H. Chung,et al. LYL1 gene amplification predicts poor survival of patients with uterine corpus endometrial carcinoma: analysis of the Cancer genome atlas data , 2018, BMC Cancer.
[25] Hamid Bolouri,et al. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions , 2017, Nature Medicine.
[26] S. Armstrong,et al. ENL links histone acetylation to oncogenic gene expression in AML , 2017, Nature.
[27] K. Yanagihara,et al. Title Expression of myeloperoxidase in acute myeloid leukemia blasts mirrors the distinct DNA methylation pattern involving the downregulation of DNA methyltransferase DNMT 3 B , 2017 .
[28] Asim Khwaja,et al. Acute myeloid leukaemia , 2016, Nature Reviews Disease Primers.
[29] H. Kantarjian. Acute myeloid leukemia—Major progress over four decades and glimpses into the future , 2016, American journal of hematology.
[30] Jean-Philippe Vert,et al. HiC-Pro: an optimized and flexible pipeline for Hi-C data processing , 2015, Genome Biology.
[31] S. Armstrong,et al. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors , 2015, Genes & development.
[32] H. Kantarjian,et al. Toward Individualized Therapy in Acute Myeloid Leukemia: A Contemporary Review. , 2015, JAMA oncology.
[33] Bandana Sharma,et al. CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer , 2014, Cell.
[34] Sridhar Ramaswamy,et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor , 2014, Nature.
[35] D. Sasaki,et al. Expression of myeloperoxidase in acute myeloid leukemia blasts mirrors the distinct DNA methylation pattern involving the downregulation of DNA methyltransferase DNMT3B , 2014, Leukemia.
[36] Charles Y. Lin,et al. Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma. , 2013, Cancer cell.
[37] R. Young,et al. Super-Enhancers in the Control of Cell Identity and Disease , 2013, Cell.
[38] David A. Orlando,et al. Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes , 2013, Cell.
[39] David A. Orlando,et al. Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers , 2013, Cell.
[40] C. Stiller,et al. Incidence, survival and prevalence of myeloid malignancies in Europe. , 2012, European journal of cancer.
[41] Guangchuang Yu,et al. clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.
[42] Steven L Salzberg,et al. Fast gapped-read alignment with Bowtie 2 , 2012, Nature Methods.
[43] Helga Thorvaldsdóttir,et al. Integrative Genomics Viewer , 2011, Nature Biotechnology.
[44] H. Harada,et al. Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations , 2009, Journal of cellular physiology.
[45] Clifford A. Meyer,et al. Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.
[46] J. Dick,et al. Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia , 2005, Leukemia.
[47] H. Kantarjian,et al. Acute myeloid leukemia , 2018, Methods in Molecular Biology.