Editorial: “Homeostasis and Allostasis of Thyroid Function”

1 Medical Department 1, Endocrinology and Diabetology, Bergmannsheil University Hospitals, Ruhr University of Bochum, Bochum, North Rhine-Westphalia, Germany, 2 Ruhr Centre of Rare Diseases (CeSER), Ruhr University of Bochum, Bochum, North Rhine-Westphalia, Germany, 3 Ruhr Centre of Rare Diseases (CeSER), Witten/Herdecke University, Bochum, North Rhine-Westphalia, Germany, 4 North Lakes Clinical, Ilkley, United Kingdom, 5 Private Consultancy, Research and Development, Yandina, QLD, Australia

[1]  S. Wajner,et al.  New Insights toward the Acute Non-Thyroidal Illness Syndrome , 2012, Front. Endocrin..

[2]  Kevin McNally,et al.  Quantitative global sensitivity analysis of a biologically based dose-response pregnancy model for the thyroid endocrine system , 2015, Front. Pharmacol..

[3]  C. C. Pazos-Moura,et al.  Hypothalamus-Pituitary-Thyroid Axis. , 2016, Comprehensive Physiology.

[4]  Melvin Khee-Shing Leow,et al.  A novel minimal mathematical model of the hypothalamus-pituitary-thyroid axis validated for individualized clinical applications. , 2014, Mathematical biosciences.

[5]  H. Price,et al.  The upper limit of the reference range for thyroid-stimulating hormone should not be confused with a cut-off to define subclinical hypothyroidism , 2009, Annals of clinical biochemistry.

[6]  Melvin Khee-Shing Leow,et al.  A mathematical model of pituitary--thyroid interaction to provide an insight into the nature of the thyrotropin--thyroid hormone relationship. , 2007, Journal of theoretical biology.

[7]  A. Pontecorvi,et al.  Clinical Concepts on Thyroid Emergencies , 2014, Front. Endocrinol..

[8]  Yossi Chait,et al.  A computational model of the human thyroid. , 2008, Mathematical biosciences.

[9]  S. Coste,et al.  Allostasis, Homeostasis, and the Costs of Physiological Adaptation , 2006 .

[10]  J. Köhrle.  Thyrotropin (TSH) action on thyroid hormone deiodination and secretion: one aspect of thyrotropin regulation of thyroid cell biology. , 1990, Hormone and metabolic research. Supplement series.

[11]  E. Stear,et al.  On identification of hypothalamo-hypophysial control and feedback relationships with the thyroid gland. , 1968, Journal of theoretical biology.

[12]  N. Koibuchi,et al.  The change in thyroid hormone signaling by altered training intensity in male rat skeletal muscle. , 2016, Endocrine journal.

[13]  Johannes W. Dietrich,et al.  Advances in applied homeostatic modelling of the relationship between thyrotropin and free thyroxine , 2017, PloS one.

[14]  M. Castro,et al.  An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction. , 2018, Thyroid : official journal of the American Thyroid Association.

[15]  Mustafa Serteser,et al.  Indirect reference intervals estimated from hospitalized population for thyrotropin and free thyroxine. , 2010, Croatian medical journal.

[16]  J. Brito,et al.  Subclinical Hypothyroidism in Elderly Individuals-Overdiagnosis and Overtreatment?: A Teachable Moment. , 2016, JAMA internal medicine.

[17]  A. Kalsbeek,et al.  Beyond the fixed setpoint of the hypothalamus-pituitary-thyroid axis. , 2014, European journal of endocrinology.

[18]  L. Petrosyan.  Relationship between high normal TSH levels and metabolic syndrome components in type 2 diabetic subjects with euthyroidism , 2015, Journal of clinical & translational endocrinology.

[19]  N. Bean,et al.  The Relationship between Population T4/TSH Set Point Data and T4/TSH Physiology , 2016, Journal of thyroid research.

[20]  Johannes W. Dietrich,et al.  Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease , 2016, European Thyroid Journal.

[21]  E. Lim,et al.  The relationship between TSH and free T₄ in a large population is complex and nonlinear and differs by age and sex. , 2013, The Journal of clinical endocrinology and metabolism.

[22]  T. Shawker,et al.  The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. , 2008, The Journal of clinical endocrinology and metabolism.

[23]  Riccardo Zucchi,et al.  Thyronamines and Derivatives: Physiological Relevance, Pharmacological Actions, and Future Research Directions. , 2016, Thyroid : official journal of the American Thyroid Association.

[24]  R. Hoermann,et al.  Reference range for thyrotropin , 2015, Nuklearmedizin.

[25]  J. DiStefano,et al.  TSH-based protocol, tablet instability, and absorption effects on L-T4 bioequivalence. , 2009, Thyroid : official journal of the American Thyroid Association.

[26]  Johannes W. Dietrich,et al.  Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model , 2013, Journal of Clinical Pathology.

[27]  Melvin Khee-Shing Leow,et al.  The homeostatic set point of the hypothalamus-pituitary-thyroid axis – maximum curvature theory for personalized euthyroid targets , 2014, Theoretical Biology and Medical Modelling.

[28]  J. Lazarus,et al.  The thyroid and its control. , 1977, Annual review of physiology.

[29]  Bruce Mcewen,et al.  Stress, Adaptation, and Disease: Allostasis and Allostatic Load , 1998, Annals of the New York Academy of Sciences.

[30]  J. Köhrle,et al.  Canonical TSH Regulation of Cathepsin-Mediated Thyroglobulin Processing in the Thyroid Gland of Male Mice Requires Taar1 Expression , 2018, Front. Pharmacol..

[31]  Annie Lumen,et al.  Evaluation of perturbations in serum thyroid hormones during human pregnancy due to dietary iodide and perchlorate exposure using a biologically based dose-response model. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.

[32]  Melvin Khee-Shing Leow,et al.  Hypothalamus–Pituitary–Thyroid Feedback Control: Implications of Mathematical Modeling and Consequences for Thyrotropin (TSH) and Free Thyroxine (FT4) Reference Ranges , 2014, Bulletin of mathematical biology.

[33]  Johannes W. Dietrich,et al.  Derivation of a multivariate reference range for pituitary thyrotropin and thyroid hormones: diagnostic efficiency compared with conventional single-reference method. , 2016, European journal of endocrinology.

[34]  L. L. Souza,et al.  Differential Regulation of Thyroid Hormone Metabolism Target Genes during Non-thyroidal Illness Syndrome Triggered by Fasting or Sepsis in Adult Mice , 2017, Front. Physiol..

[35]  G. Berghe.  Non-Thyroidal Illness in the ICU: A Syndrome with Different Faces , 2014 .

[36]  R. Granese,et al.  Serum Thyrotropin and Phase of the Menstrual Cycle , 2017, Front. Endocrinol..

[37]  Robert B. DarofL.  Supplements , 1992, Neurology.

[38]  J. W. Dietrich,et al.  THYROTROPIC FEEDBACK CONTROL: EVIDENCE FOR AN ADDITIONAL ULTRASHORT FEEDBACK LOOP FROM FRACTAL ANALYSIS , 2004, Cybern. Syst..

[39]  R. Utiger,et al.  Regulation of the pituitary-thyroid axis in man: relationship of TSH concentration to concentration of free and total thyroxine in plasma. , 1967, The Journal of clinical endocrinology and metabolism.

[40]  Johannes W. Dietrich,et al.  Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects , 2015, Hormone and Metabolic Research.

[41]  Johannes W. Dietrich,et al.  Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment , 2014, Clinical endocrinology.

[42]  Simon X. Han,et al.  THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements. , 2016, Thyroid : official journal of the American Thyroid Association.

[43]  J. Franklyn,et al.  The relationship between serum TSH and free T4 in older people , 2012, Journal of Clinical Pathology.

[44]  Johannes W. Dietrich,et al.  Nonthyroidal Illness Syndrome in Cardiac Illness Involves Elevated Concentrations of 3,5-Diiodothyronine and Correlates with Atrial Remodeling , 2015, European Thyroid Journal.

[45]  H. J. Gundersen,et al.  Circadian and 30 minutes variations in serum TSH and thyroid hormones in normal subjects. , 1978, Acta endocrinologica.

[46]  J. Köhrle,et al.  Thyronamines--past, present, and future. , 2011, Endocrine reviews.

[47]  Johannes W. Dietrich,et al.  TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis , 2012, Journal of thyroid research.

[48]  K. Prank,et al.  Circadian and pulsatile TSH secretion under physiological and pathophysiological conditions. , 1990, Hormone and metabolic research. Supplement series.

[49]  Johannes W. Dietrich,et al.  The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome , 2008, BMC endocrine disorders.

[50]  L. Wartofsky,et al.  Optimal thyrotropin level: normal ranges and reference intervals are not equivalent. , 2005, Thyroid : official journal of the American Thyroid Association.

[51]  F. Arzideh,et al.  Indirect reference intervals of plasma and serum thyrotropin (TSH) concentrations from intra-laboratory data bases from several German and Italian medical centres , 2011, Clinical chemistry and laboratory medicine.

[52]  M. Andersen,et al.  A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult rat: evaluation of iodide deficiency. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[53]  P. Sterling,et al.  Allostasis: A new paradigm to explain arousal pathology. , 1988 .

[54]  F. Goglia,et al.  Thyroid: biological actions of 'nonclassical' thyroid hormones. , 2014, The Journal of endocrinology.