Chasing the treasures of the sea - bacterial marine natural products.
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[1] D. Faulkner,et al. Marine natural products. , 2000, Natural product reports.
[2] K. S. Lam,et al. Discovery and development of the anticancer agent salinosporamide A (NPI-0052). , 2009, Bioorganic & medicinal chemistry.
[3] E. Schmidt,et al. Using marine natural products to discover a protease that catalyzes peptide macrocyclization of diverse substrates. , 2009, Journal of the American Chemical Society.
[4] Susana P. Gaudêncio,et al. The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species. , 2009, Angewandte Chemie.
[5] Susana P. Gaudêncio,et al. Ammosamides A and B target myosin. , 2009, Angewandte Chemie.
[6] T. Hemscheidt,et al. Post‐translational Modification in Microviridin Biosynthesis , 2008, Chembiochem : a European journal of chemical biology.
[7] B. Moore. Extending the biosynthetic repertoire in ribosomal peptide assembly. , 2008, Angewandte Chemie.
[8] P. Jensen,et al. Marineosins A and B, cytotoxic spiroaminals from a marine-derived actinomycete. , 2008, Organic letters.
[9] M. Fischbach,et al. Total Biosynthesis: in vitro Reconstitution of Polyketide and Nonribosomal Peptide Pathways , 2008 .
[10] Hai Deng,et al. The fluorinase, the chlorinase and the duf-62 enzymes. , 2008, Current opinion in chemical biology.
[11] E. Dittmann,et al. Ribosomal synthesis of tricyclic depsipeptides in bloom-forming cyanobacteria. , 2008, Angewandte Chemie.
[12] Martina Werneburg,et al. Chemoenzymatic Total Synthesis of the Antiproliferative Polyketide (+)‐(R)‐Aureothin , 2008, Chembiochem : a European journal of chemical biology.
[13] B. Moore,et al. Advances in and applications of proteasome inhibitors. , 2008, Current opinion in chemical biology.
[14] S. Schreiber,et al. Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor. , 2008, Journal of the American Chemical Society.
[15] Xuedong Liu,et al. A concise total synthesis of largazole, solution structure, and some preliminary structure activity relationships. , 2008, Organic letters.
[16] T. Thomas,et al. Unlocking the diversity and biotechnological potential of marine surface associated microbial communities. , 2008, Current opinion in microbiology.
[17] B. Moore,et al. Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors. , 2008, Journal of the American Chemical Society.
[18] Hendrik Luesch,et al. Total synthesis and molecular target of largazole, a histone deacetylase inhibitor. , 2008, Journal of the American Chemical Society.
[19] P. Dorrestein,et al. Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. , 2008, Molecular bioSystems.
[20] Bradley S Moore,et al. Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome. , 2008, Angewandte Chemie.
[21] Rebecca A. Medina,et al. Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp. , 2008, Journal of the American Chemical Society.
[22] J. Ravel,et al. A global assembly line for cyanobactins. , 2008, Nature chemical biology.
[23] P. Dorrestein,et al. Biosynthetic origin of natural products isolated from marine microorganism–invertebrate assemblages , 2008, Proceedings of the National Academy of Sciences.
[24] W. Gerwick,et al. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8 , 2008, Proceedings of the National Academy of Sciences.
[25] E. Dittmann,et al. Microcyclamide Biosynthesis in Two Strains of Microcystis aeruginosa: from Structure to Genes and Vice Versa , 2008, Applied and Environmental Microbiology.
[26] B. Moore,et al. Unraveling the biosynthesis of the sporolide cyclohexenone building block. , 2008, Journal of the American Chemical Society.
[27] V. Paul,et al. Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp. , 2008, Journal of the American Chemical Society.
[28] William Fenical,et al. The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp. , 2008, Organic letters.
[29] W. Gerwick,et al. GNAT-Like Strategy for Polyketide Chain Initiation , 2007, Science.
[30] A. Bull,et al. Marine actinobacteria: new opportunities for natural product search and discovery. , 2007, Trends in microbiology.
[31] Michelle L. Reyzer,et al. MALDI imaging mass spectrometry: molecular snapshots of biochemical systems , 2007, Nature Methods.
[32] Qian Cheng,et al. Enzymatic total synthesis of enterocin polyketides , 2007, Nature Chemical Biology.
[33] William Fenical,et al. Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica , 2007, Proceedings of the National Academy of Sciences.
[34] Christopher D Reeves,et al. Combinatorial biosynthesis for drug development. , 2007, Current opinion in microbiology.
[35] U. Hentschel,et al. An environmental genomics perspective on the diversity and function of marine sponge-associated microbiota. , 2007, Current opinion in microbiology.
[36] P. Dorrestein,et al. Molecular Basis for Chloronium-mediated Meroterpene Cyclization , 2007, Journal of Biological Chemistry.
[37] Lik Tong Tan,et al. Bioactive natural products from marine cyanobacteria for drug discovery. , 2007, Phytochemistry.
[38] D. Newman,et al. Natural products as sources of new drugs over the last 25 years. , 2007, Journal of natural products.
[39] B. Moore,et al. Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica. , 2007, Organic letters.
[40] Sy Teisan,et al. Salinosporamides D-J from the marine actinomycete Salinispora tropica, bromosalinosporamide, and thioester derivatives are potent inhibitors of the 20S proteasome. , 2007, Journal of natural products.
[41] William Fenical,et al. Species-Specific Secondary Metabolite Production in Marine Actinomycetes of the Genus Salinispora , 2006, Applied and Environmental Microbiology.
[42] Jacques Ravel,et al. Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians , 2006, Nature chemical biology.
[43] Paul R Jensen,et al. Developing a new resource for drug discovery: marine actinomycete bacteria , 2006, Nature chemical biology.
[44] R. Huber,et al. Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. , 2006, Journal of the American Chemical Society.
[45] M. K. Harper,et al. A Central Strategy for Converting Natural Products into Fluorescent Probes , 2006, Chembiochem : a European journal of chemical biology.
[46] P. Long,et al. Shotgun Cloning and Heterologous Expression of the Patellamide Gene Cluster as a Strategy to Achieving Sustained Metabolite Production , 2005, Chembiochem : a European journal of chemical biology.
[47] D. Sherman,et al. Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products , 2005, Chembiochem : a European journal of chemical biology.
[48] E. Corey,et al. An efficient, stereocontrolled synthesis of a potent omuralide-salinosporin hybrid for selective proteasome inhibition. , 2005, Journal of the American Chemical Society.
[49] U. Szewzyk,et al. Rapid screening and dereplication of bacterial isolates from marine sponges of the Sula Ridge by Intact-Cell-MALDI-TOF mass spectrometry (ICM-MS) , 2005, Applied Microbiology and Biotechnology.
[50] J. Eisen,et al. Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[51] S. Neuteboom,et al. Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor. , 2005, Journal of medicinal chemistry.
[52] Matthias Platzer,et al. Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[53] Jörn Piel,et al. A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[54] B. Moore,et al. Discovery and characterization of a marine bacterial SAM-dependent chlorinase. , 2008, Nature chemical biology.
[55] V. Torchilin. Multifunctional nanocarriers. , 2006, Advanced drug delivery reviews.
[56] D. Faulkner. Marine natural products. , 2000, Natural product reports.