Plasma cortisol and growth hormone responses to intravenous characterization.

Plasma cortisol and growth hormone (HGH) responses to venous catheterization were studied in 29 volunteer subjects. Repeat characterizations were performed in 18 individuals. Mean plasma cortisol levels were significantly elevated during the first hour of the initial catheterization experience. Morning and afternoon levels of cortisol were not distinguishable during the first catheterization, but PM levels were significantly lower than AM levels during the second catheterization experience. Growth hormone responses were much more variable than cortisol and were distributed logarithmically. Growth hormone responses tended to parallel cortisol responses during the first catheterization experience. Individuals who listed more symptoms in response to venipuncture and catheterization after finishing their first catheterization had significantly higher cortisol and growth hormone levels during this experience. These data suggest a definite endocrine adaptation to catheterization by the second or third hour of the experience.

[1]  W. Daughaday,et al.  Measurement of the Binding Capacity of Corticosteroid-Binding Globulin in Human Plasma , 1962 .

[2]  J. Landon,et al.  Growth Hormone Secretion in Response to Stress in Man , 1966, Nature.

[3]  E. Knobil,et al.  Growth hormone secretion in the unanesthetized rhesus monkey in response to noxious stimuli. , 1967, Endocrinology.

[4]  J W Mason,et al.  A Review of Psychoendocrine Research on the Pituitary‐Adrenal Cortical System , 1968, Psychosomatic medicine.

[5]  R. Rose,et al.  Psychological state and body size as determinants of 17-OHCS excretion. , 1968, Archives of internal medicine.

[6]  S. Berson,et al.  HGH and ACTH Secretory Responses to Stress , 1969, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[7]  W. Greene,et al.  Psychologic Correlates of Growth Hormone and Adrenal Secretory Responses of Patients Undergoing Cardiac Catheterization , 1970, Psychosomatic medicine.

[8]  T F Gallagher,et al.  Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. , 1971, The Journal of clinical endocrinology and metabolism.

[9]  G. Brown,et al.  Hypothalamic mediation of growth hormone and adrenal stress response in the squirrel monkey. , 1971, Endocrinology.

[10]  C. Migeon,et al.  Determination of integrated plasma concentrations and true secretion rates of human growth hormone. , 1971, The Journal of clinical endocrinology and metabolism.

[11]  G. Brown,et al.  Patterns of growth hormone and cortisol responses to psychological stress in the squirrel monkey. , 1971, Endocrinology.

[12]  H. Ruder,et al.  A radioimmunoassay for cortisol in plasma and urine. , 1972, The Journal of clinical endocrinology and metabolism.

[13]  T. Kotchen,et al.  Plasma Cortisol and Norepinephrine Responses in Anticipation of Muscular Exercise , 1973, Psychosomatic medicine.

[14]  C. Migeon,et al.  Integrated Concentration and Diurnal Variation of Plasma Cortisol1 , 1973 .

[15]  J. Mason,et al.  Plasma Growth Hormone Response to Capture and Venipuncture in Caged Monkeys 1 , 1974, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[16]  L. Levi,et al.  Emotions, their parameters and measurement , 1975 .