RUFY3 regulates endolysosomes perinuclear positioning, antigen presentation and migration in activated phagocytes

[1]  J. Bonifacino,et al.  Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes , 2023, Cell reports.

[2]  N. Liv,et al.  RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes , 2022, The Journal of cell biology.

[3]  V. Haucke,et al.  Phosphoinositides as membrane organizers , 2022, Nature Reviews Molecular Cell Biology.

[4]  L. Weisman,et al.  Roles of PIKfyve in multiple cellular pathways , 2022, Current Opinion in Cell Biology.

[5]  J. Bonifacino,et al.  RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin , 2022, Nature Communications.

[6]  Prateek Chawla,et al.  RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning , 2022, Nature Communications.

[7]  P. Lučin,et al.  Early Endosomal Vps34-Derived Phosphatidylinositol-3-Phosphate Is Indispensable for the Biogenesis of the Endosomal Recycling Compartment , 2022, Cells.

[8]  J. Mintern,et al.  Spatiotemporal Adaptations of Macrophage and Dendritic Cell Development and Function. , 2022, Annual review of immunology.

[9]  S. Edge,et al.  Low RUFY3 expression level is associated with lymph node metastasis in older women with invasive breast cancer , 2022, Breast Cancer Research and Treatment.

[10]  J. Gorvel,et al.  The Salmonella effector SifA initiates a kinesin-1 and kinesin-3 recruitment process mirroring that mediated by Arl8a/b. , 2021, Journal of Cell Science.

[11]  M. Malissen,et al.  Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines , 2021, Journal of Visualized Experiments.

[12]  J. Poschmann,et al.  Alveolar Macrophages: Adaptation to Their Anatomic Niche during and after Inflammation , 2021, Cells.

[13]  Yang Zhang,et al.  RUFY3 promotes the progression of hepatocellular carcinoma through activating NF-κB-mediated epithelial-mesenchymal transition , 2021, Aging.

[14]  O. Bakke,et al.  Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton , 2021, Journal of cell science.

[15]  David G. McEwan,et al.  RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages , 2021, Royal Society Open Science.

[16]  J. Bonifacino,et al.  ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1 , 2020, Current Biology.

[17]  P. Pierre,et al.  The RUFYs, a Family of Effector Proteins Involved in Intracellular Trafficking and Cytoskeleton Dynamics , 2020, Frontiers in Cell and Developmental Biology.

[18]  K. Asehnoune,et al.  Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis , 2020, Nature Immunology.

[19]  Rik van der Kant,et al.  SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport , 2020, The EMBO journal.

[20]  Marcus J. Fantham,et al.  The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes , 2020, bioRxiv.

[21]  A. Ballabio,et al.  Lysosomes as dynamic regulators of cell and organismal homeostasis , 2019, Nature Reviews Molecular Cell Biology.

[22]  J. Bonifacino,et al.  Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling , 2019, Nature Cell Biology.

[23]  David J Simon,et al.  Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration , 2019, Neuron.

[24]  J. Bonifacino,et al.  Lysosome Positioning Influences mTORC2 and AKT Signaling. , 2019, Molecular cell.

[25]  D. McGavern,et al.  Advances in Meningeal Immunity , 2018, Trends in Molecular Medicine.

[26]  J. Bonifacino,et al.  A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability , 2017, The Journal of cell biology.

[27]  A. Ballabio,et al.  Lysosome signaling controls the migration of dendritic cells , 2017, Science Immunology.

[28]  H. Kaur,et al.  Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication , 2017, PLoS pathogens.

[29]  H. Kaur,et al.  The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes , 2017, The Journal of cell biology.

[30]  J. Bonifacino,et al.  BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks. , 2016, Cell reports.

[31]  J. Casanova,et al.  Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation , 2016, Cell.

[32]  A. Simonsen,et al.  Phosphoinositide‐binding proteins in autophagy , 2016, FEBS letters.

[33]  J. Neefjes,et al.  An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport , 2016, Cell.

[34]  A. Sharpe,et al.  Roles of CD48 in regulating immunity and tolerance. , 2016, Clinical immunology.

[35]  Wuyang Wang,et al.  A Molecular Mechanism to Regulate Lysosome Motility for Lysosome Positioning and Tubulation , 2016, Nature Cell Biology.

[36]  Manuel A. S. Santos,et al.  RUN and FYVE domain–containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4 , 2015, The Journal of cell biology.

[37]  O. Bénichou,et al.  Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells , 2015, Nature Communications.

[38]  C. Bucci,et al.  Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth , 2015, Nature.

[39]  P. Ricciardi-Castagnoli,et al.  MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b , 2015, The Journal of Immunology.

[40]  B. Maček,et al.  PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection. , 2015, Cell host & microbe.

[41]  Xinyi Liu,et al.  Rufy3, a protein specifically expressed in neurons, interacts with actin‐bundling protein Fascin to control the growth of axons , 2014, Journal of neurochemistry.

[42]  D. Teis,et al.  The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration , 2014, The Journal of cell biology.

[43]  Y. Kitagishi,et al.  RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking , 2013, International journal of molecular sciences.

[44]  K. Liestøl,et al.  Production of phosphatidylinositol 5‐phosphate via PIKfyve and MTMR3 regulates cell migration , 2013, EMBO reports.

[45]  J. Kay,et al.  Rab7 and Arl8 GTPases are Necessary for Lysosome Tubulation in Macrophages , 2012, Traffic.

[46]  M. Mann,et al.  Novel Murine Dendritic Cell Lines: A Powerful Auxiliary Tool for Dendritic Cell Research , 2012, Front. Immun..

[47]  S. Munro,et al.  Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1 , 2011, Developmental cell.

[48]  Veronica Canadien,et al.  Salmonella exploits Arl8B‐directed kinesin activity to promote endosome tubulation and cell‐to‐cell transfer , 2011, Cellular microbiology.

[49]  N. Hacohen,et al.  Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b , 2011, Immunity.

[50]  P. Cresswell,et al.  A Genome-wide Multidimensional RNAi Screen Reveals Pathways Controlling MHC Class II Antigen Presentation , 2011, Cell.

[51]  Cahir J. O'Kane,et al.  Lysosomal positioning coordinates cellular nutrient responses , 2011, Nature Cell Biology.

[52]  S. Drevensek,et al.  SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin‐1‐Dependent Vacuolar Membrane Exchanges , 2010, Traffic.

[53]  O. Gascuel,et al.  SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. , 2010, Molecular biology and evolution.

[54]  D. Koller,et al.  The Immunological Genome Project: networks of gene expression in immune cells , 2008, Nature Immunology.

[55]  J. Keane,et al.  T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. , 2007, Immunity.

[56]  B. Reizis,et al.  Notch–RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen , 2007, The Journal of experimental medicine.

[57]  K. Wright,et al.  MHC class II transactivator (CIITA) expression is upregulated in multiple myeloma cells by IFN-γ , 2007 .

[58]  F. Cordelières,et al.  A guided tour into subcellular colocalization analysis in light microscopy , 2006, Journal of microscopy.

[59]  P. Lécine,et al.  The Salmonella effector protein PipB2 is a linker for kinesin-1 , 2006, Proceedings of the National Academy of Sciences.

[60]  S. Munro,et al.  An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility , 2006, Journal of Cell Science.

[61]  Harald Stenmark,et al.  Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes , 2004, Journal of Cell Science.

[62]  E. Weber,et al.  Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[63]  S. Wittmer,et al.  Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells , 2000, The Journal of experimental medicine.

[64]  Rein Aasland,et al.  FYVE fingers bind PtdIns(3)P , 1998, Nature.

[65]  R. Steinman,et al.  Developmental regulation of MHC class II transport in mouse dendritic cells , 1997, Nature.