Akt, mTOR and NF‐&kgr;B pathway activation in Treponema pallidum stimulates M1 macrophages

[1]  M. LeDoyt,et al.  IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages , 2017, Front. Immunol..

[2]  A. Wojas-Pelc,et al.  Robust pro-inflammatory immune response is associated with serological cure in patients with syphilis: an observational study , 2016, Sexually Transmitted Infections.

[3]  Liang Zhao,et al.  The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses , 2015, Molecular Cancer.

[4]  Shuyan Liu,et al.  MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma , 2015, Oncotarget.

[5]  F. Tian,et al.  mTOR mediates the cross-talk of macrophage polarization and autophagy in atherosclerosis. , 2014, International journal of cardiology.

[6]  Gefei Wang,et al.  PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b , 2014, PloS one.

[7]  F. Lafeber,et al.  Hemarthrosis in hemophilic mice results in alterations in M1-M2 monocyte/macrophage polarization. , 2014, Thrombosis research.

[8]  Dinender K. Singla,et al.  SMAD-PI3K-Akt-mTOR Pathway Mediates BMP-7 Polarization of Monocytes into M2 Macrophages , 2013, PloS one.

[9]  E. Herrmann,et al.  Macrophage activation is a prognostic parameter for variceal bleeding and overall survival in patients with liver cirrhosis. , 2013, Journal of hepatology.

[10]  A. Schober,et al.  The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155–Dependent Pathway During Atherosclerosis , 2013, Circulation.

[11]  YuanyuanWei,et al.  The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155–Dependent Pathway During Atherosclerosis , 2013 .

[12]  Philip N. Tsichlis,et al.  Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization , 2012, Proceedings of the National Academy of Sciences.

[13]  X. Bai,et al.  Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway. , 2012, Cancer research.

[14]  J. Luyendyk,et al.  Genetic Analysis of the Role of the PI3K-Akt Pathway in Lipopolysaccharide-Induced Cytokine and Tissue Factor Gene Expression in Monocytes/Macrophages1 , 2008, The Journal of Immunology.

[15]  Z. Zhan,et al.  Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. , 2007, Rheumatology.

[16]  D. Šmajs,et al.  Diagnosis of syphilis by polymerase chain reaction and molecular typing of Treponema pallidum , 2006 .

[17]  Korinne Di Leo,et al.  Production of tumor necrosis factor alpha by Treponema pallidum, Borrelia burgdorferi s.l., and Leptospira interrogans in isolated rat Kupffer cells. , 2004, FEMS immunology and medical microbiology.

[18]  W. V. Voorhis,et al.  Lesions of primary and secondary syphilis contain activated cytolytic T cells , 1996, Infection and immunity.

[19]  W. V. Voorhis,et al.  Primary and Secondary Syphilis Lesions Contain mRNA for Thl Cytokines , 1996 .

[20]  S. Lukehart,et al.  Macrophage-mediated killing of opsonized Treponema pallidum. , 1992, The Journal of infectious diseases.