Fatal anaphylaxis due to fire ant stings.

Imported fire ants (Solenopsis invicta and Solenopsis richteri) are the source of a potentially lethal environmental hazard in the southeastern United States. Because of their resistance to natural and chemical control, fire ants can overwhelm their environment, causing destruction of land and animals. Fire ants can also cause a variety of health problems in humans, ranging from simple stings to anaphylaxis and death. We present a case of a 30-year-old woman who died of anaphylaxis following multiple fire ant stings. At autopsy, multiple skin lesions characteristic of those produced by fire ant stings were present on her arm. Postmortem blood samples were positive for imported fire ant venom-specific IgE antibodies (5654 ng/ml) and tryptase (12 ng/ml). Deaths caused by imported fire ant stings are rare but are likely to become more common as the fire ant population expands. In this report, we review deaths due to fire ant stings, discuss postmortem laboratory findings, and stress the importance of recognizing the characteristic skin lesions produced by fire ants.

[1]  J. Butts,et al.  Elevated postmortem tryptase in the absence of anaphylaxis. , 1995, Journal of forensic sciences.

[2]  L. Schwartz,et al.  Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis. , 1989, The Journal of clinical investigation.

[3]  Austen Kf,et al.  Fatal Systemic Anaphylaxis in Man , 1964 .

[4]  M. Ansari,et al.  Postmortem diagnosis of acute anaphylaxis by serum tryptase analysis. A case report. , 1993, American journal of clinical pathology.

[5]  Donald D. Hoffman,et al.  Allergy to Imported Fire Ants , 1989, Southern medical journal.

[6]  A. Smith,et al.  Allergens in Hymenoptera venom. XXII. Comparison of venoms from two species of imported fire ants, Solenopsis invicta and richteri. , 1990, The Journal of allergy and clinical immunology.

[7]  Triplett Rf Sensitivity to the Imported Fire Ant: Successful Treatment with Immunotherapy , 1973 .

[8]  P. Hudson,et al.  Demonstration of IgE and IgG antibodies against venoms in the blood of victims of fatal sting anaphylaxis. , 1983, The Journal of allergy and clinical immunology.

[9]  N. Lind,et al.  Mechanism of action of fire ant (Solenopsis) venoms. I. Lytic release of histamine from mast cells. , 1982, Toxicon : official journal of the International Society on Toxinology.

[10]  H. Schwartz,et al.  Studies in stinging insect hypersensitivity: postmortem demonstration of antivenom IgE antibody in possible sting-related sudden death. , 1986, American journal of clinical pathology.

[11]  D. Hoffman,et al.  Allergens in Hymenoptera venom. XX. Isolation of four allergens from imported fire ant (Solenopsis invicta) venom. , 1988, The Journal of allergy and clinical immunology.

[12]  M. Blum,et al.  Chemical, insecticidal and antibiotic properties of fire ant venom. , 1958, Science.

[13]  W. P. Horen Insect and scorpion sting. , 1972, JAMA.

[14]  R. Lockey,et al.  Multiple stings by imported fire ants (Solenopsis invicta), without systemic effects. , 1989, Southern medical journal (Birmingham, Ala. Print).

[15]  H. Parrish ANALYSIS OF 460 FATALITIES FROM VENOMOUS ANIMALS IN THE UNITED STATES , 1963, The American journal of the medical sciences.

[16]  W Q Sturner,et al.  Laboratory investigation of deaths due to anaphylaxis. , 1991, Journal of forensic sciences.

[17]  H. Wittig,et al.  Hypersensitivity to the imported fire ant. A report of 49 cases. , 1975, The Journal of allergy and clinical immunology.

[18]  T. Liu,et al.  Protein components of fire ant venom (Solenopsis invicta). , 1979, Toxicon : official journal of the International Society on Toxinology.

[19]  R. Rhoades,et al.  Survey of fatal anaphylactic reactions to imported fire ant stings. Report of the Fire Ant Subcommittee of the American Academy of Allergy and Immunology. , 1989, The Journal of allergy and clinical immunology.

[20]  R. Bowen INSECTS AND ALLERGIC PROBLEMS , 1951, Southern medical journal (Birmingham, Ala. Print).

[21]  C. S. Lofgren,et al.  Incidence of stings or bites of the red imported fire ant (Hymenoptera: Formicidae) and other arthropods among patients at Ft. Stewart, Georgia, USA. , 1982, Journal of medical entomology.

[22]  H. S. Earl,et al.  Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. , 1987, The New England journal of medicine.

[23]  D. Hoffman,et al.  Allergens in Hymenoptera venom. XXI. Cross-reactivity and multiple reactivity between fire ant venom and bee and wasp venoms. , 1988, The Journal of allergy and clinical immunology.

[24]  C. S. Lofgren,et al.  Red imported fire ants (Hymenoptera: Formicidae): frequency of sting attacks on residents of Sumter County, Georgia. , 1981, Journal of medical entomology.

[25]  R. Lockey Systemic reactions to stinging ants. , 1974, The Journal of allergy and clinical immunology.